Life Cell Imaging Market – A step towards improvement in drug discovery
Cellular imaging refers to the techniques that allows the detection and analysis of various cellular organelles and macromolecules using a light-based or electron based microscopes. These are then mainly analyzed through computer based programs. Apart from the structural organization and orientation of organs and cells in organisms, dynamic processes contributes a major part in understanding the function and mechanism of a biological entity. Live life cell imaging refers to the non-invasive techniques such as optical methods that help visualize functional behavior of the cells with the help of high-end imaging instruments such as stereo microscopes. The high-content screening systems have become a popular analytical tool for elucidation of biological mechanisms as well as for the study of dynamic functions of the cells. The life cell imaging systems are used in order to study the living cells through the images obtained from life cell imaging instruments.
Rise in development of cancer drugs is a crucial factor to propel the market growth
Accelerating drug development has become a crucial factor so as to come up with new and advanced drugs that has potential to treat cancer. Understanding the cellular functionality of these oncogenic substances and tumor cells is thus a very important step in the drug development and requires high-powered microscopes to understand the dynamic structures so as to develop a drug against the cancer causing agents. The government as well as various federal agencies play important roles funding imaging systems to support and clinical care and research. For instance, the National Science and Technology Council, which is an Interagency Working Group on Medical Imaging (IWGMI) established in 2015 develops a roadmap for medical-imaging research and development in the U.S. that helps in generating better outcome of healthcare and optimize the costs.
The global life life cell imaging market was valued at US$ 4.4 billion in 2016 and is expected to witness a robust CAGR of 8.60% over the forecast period (2017 - 2025).
Figure 1. Global Life Cell Imaging Market Share by Region 2016 (%)
Advancements in live life cell imaging microscopes to create a highly competitive scenario among market players
The use of quantum dots that are nanoparticles with fluorescent properties offering advantages over organic fluorophores is emerging as a potential technique that is incorporated recently in the biological imaging microscopes. Moreover, scientists in the University of Rochester in 2017 demonstrated for the use of quantum dots as photoredox catalysts for the generation of carbon-carbon bonds through light emission and the technique is suggested to be helpful in simplifying the synthesis of novel compounds in the future. North America is expected to be the regional dominator throughout the forecast period, followed by Europe owing to high capitalization in imaging systems as well as intensive research and development to improve the imaging quality and data functionality. For instance, Luxendo- a spinoff of European Molecular Biology Laboratory raised US$ 9.4 Mn in January 2017 to commence international sales of its unique single plane illumination microscopy technology in order to take over confocal microscopes in biology research. The major players operating global life life cell imaging market includes Leica Microsystems, Carl Zeiss Meditec AG, Nikon Instruments, Inc., Thermofisher Scientific, Inc., Olympus Corporation, GE Healthcare, Sigma-Aldrich Corporation, Molecular Devices LLC, PerkinElmer, Inc. and Becton-Dickinson and Company.
The global life cell imaging industry has observed a notable growth over the last few decades due to significant increase in the demand for life cell imaging techniques for the study of cancer, neuroscience and drug discovery. Cellular imaging involves use of techniques that enable the detection and analysis of cellular organelles and macromolecules through light- or electron-based microscopes. Cell imaging is rapidly evolving as new technologies are being introduced such as light sheet microscopy, intra-vital microscopy, environmental scanning electron microscopy and high throughput microscopy. Furthermore, life cell imaging use fluorophore labeled molecules, fluorescent dyes and recombinant plasmid systems for imaging expression, transport, co-localization and degradation in either living or fixed cells. In addition, cellular structures and functions can be visually detected using methods such as wide field fluorescence and fluorescence resonance energy transfer (FRET) microscopy.
The life cell imaging market is gaining significant traction due to rising adoption of techniques in various fields such as stem cell biology, neurobiology, developmental biology, cell biology, and oncology, drug discovery, and electro physiology. Furthermore, life cell imaging has emerged as a potential tool that helps provide insights into dynamic processes in living cells and cell function with the help of agents such as green fluorescent protein (GFP) and multicolored probes that precisely label molecules and directly probe its function in live cells by light microscopy. Due to the visualization ability of the imaging tools, the dynamics of protein vesicles, organelles, cells and tissue has provided new insights into how cells function. However, the factors such as shortage of skilled professionals and high cost of the advanced microscopes hinder market growth to a certain extent.
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