Single-use Bioprocessing Systems Market, by Product Type (Instruments and Accessories), by Application (Monoclonal Antibody Production, Vaccine Production, Patient Specific Cell Therapies and Other Applications), by End User (Biotechnology and Pharmaceutical Companies, Research & Academic Research Institutes, and Contract Research Organizations(CRO) & Contract Manufacturing Organizations(CMO)), and by Region - Size, Share, and Forecast to 2026

  • Published On : Jun 2018 |
  • Pages : 160 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Single-use Bioprocessing Systems Market – Insights

Single-use bioprocessing system is a disposable bioprocessing process in which the systems such as disposable bioreactor, single-use bags, and disposable filters are disposed after use instead of cleaning or sterilization. Single-use systems are majorly adapted in upstream and downstream bioprocessing, owing to its benefits over conventional bioprocessing systems, which includes reduction of cost, increased speed of implementation, and reduced risk of cross-contamination. Moreover, increasing adoption of single-use bioprocessing systems, increasing investment in research and development (R&D) sector by various government and private organizations, increasing demand for single-use systems in biopharmaceutical sector and increasing number of key players offering technologically advanced bioprocessing products are projected to augment growth of the single-use bioprocessing systems market over the forecast period.

The global single-use bioprocessing systems market was valued at US$ 2.80 billion in 2018, and is expected to witness a CAGR of 17.2% over the forecast period (2018 – 2026).

Fig: Global Single-use Bioprocessing Systems Market Share (%), By Product Type

single-use bioprocessing systems market

Source: Coherent Market Insights Analysis (2018)

Increasing Adoption of Single-Use Bioprocessing Technologies is expected to Drive Growth of the Single-use Bioprocessing Systems Market

Increasing demand for biologics, need for production capacity expansion, patent expiry of blockbuster molecules, and a limited number of potential products in the pipeline have driven the companies to adopt new technologies such as single-use bioprocessing systems. Single-use equipment offers various benefits making biomanufacturing process more efficient and cost effective. Single-use technologies is a rapidly evolved and adopted owing to their ability to offer significant cost reduction, ease of disposable, time saving, less energy and water demand for bioprocessing process, reduced risk of contamination and increase in productivity. Moreover, single-use bioprocessing systems reduces the initial investments and research and development (R&D) cost involved in the manufacturing of biologics and biopharmaceuticals. Conventional manufacturing of biopharmaceuticals and biologics involves use of stainless steel-based bioreactor and their subcomponents. Most of these products require sterilization and associated units for manufacturing contamination-free bio-products and biologics, which significantly increases overall investment cost. Moreover, according to the data published in Bioprocess International Journal in December 2015, single-use bioprocessing systems eliminate additional investment cost, as sterilization is not required. This lower around 40% of investment costs compared to stainless steel facility.

Furthermore, increasing research and development investment by various government and private organizations in therapeutic, biopharmaceutical, and clinical diagnostics area is expected to propel demand for efficient and cost-effective bioprocessing pilot study plants designed with single-use bioprocessing technologies. For instance, according to Farmaindustria: the National Business Association of the Pharmaceutical Industry in Spain, pharmaceutical companies in Spain invested US$ 1,154.7 million in research and development activities in 2014. Among these total amount invested, more than half of the amount (US$ 591.9, 51.26%) was allocated to fund clinical trials, which is the 63% increase in investment over the last decade (2004 to 2014).

Furthermore, National Cancer Institute (NCI) invested US$ 749.8 million, US$ 769.2 million and US$ 801 million on cancer related clinical trials in 2014, 2015, and 2016, respectively. Moreover, according to the World Intellectual Property Indicators 2017 report, Asia (64.6%) accounted to register highest percentage of patent applications for 2016, followed by North America (20.5%), Europe (11.3%), Latin America and the Caribbean (2%), Oceania (1.1%), and Africa (0.5%). According to the same source, in 2016, China registered highest number of patents (1,338,503 patent applications), with 21.5% annual growth. Moreover, increasing R&D activities coupled with increasing adoption of disposable systems is expected to drive growth of single-use bioprocessing systems market.

Increasing Demand for Biopharmaceuticals is Driving Growth of Single-use Bioprocessing Systems Market

Single-use bioprocessing systems are increasingly adopted by biopharmaceutical industry owing to their increased efficiency, low cost investment, and low maintenance, with significant time savings during bioprocessing process. For instance, according to the Office for National Statistics(ONS): 2014 Business Enterprise Research and Development data findings, in 2013, the pharmaceutical industry in U.K. accounted for 22% of all research and development (R&D) expenditure, investing around US$ 6.76 billion. According to The International Trade Administration (ITA), the U.S. accounted for the largest market for biopharmaceutical sector, accounting for 17% of all domestic research and development (R&D) funded by U.S. private organizations, with added an estimated US$ 1.2 trillion in economic output in 2014. Furthermore, according to the 14th Annual report and Survey of Biopharmaceutical Manufacturing report: 2017, biopharmaceutical industry exhibit an overall consistent 14-15% industry growth. Moreover, increasing investment by various government organizations to boost the biopharmaceutical industry is expected to increase the demand for biopharmaceutical; thereby accelerating demand for single-use bioprocessing systems in near future. For instance, in June 2017, Ministry of Science and Technology, India; launched US$ 250 million program to promote the production of biological drugs and thereby boost India's biopharmaceutical industry.

However, extractability and leachability issues related to single-use bioprocessing systems is expected to hinder the growth of single-use bioprocessing systems market over the forecast period. Single-use systems bioreactors are more susceptible to problems associated with compound leaching into the bioprocessing fluid as compared to conventional stainless steel bioreactor. Leachables are any compounds, both organic or inorganic that migrate into drug product formulations from the container closure as a result of direct contact with the formulation. With the rapid expansion of single-use systems for bioprocessing, plastics-based bioprocessing reactors are extensively used in biopharmaceutical production. According to the data published in American Pharmaceutical Review Journal in December 2017, leachables from single-use bioprocessing assemblies can adversely affect cell culture performance. Furthermore, excessive quantities of leached bDtBPP were shown to be toxic to various array of cell lines. Moreover, evaluation of leachables to reduce patient safety risks is necessary during single-use bioprocessing.

Key players operating in single-use bioprocessing systems market include Compagnie de Saint-Gobain S.A., Thermo Fisher Scientific Inc., Applikon Biotechnology BV, Parker-Hannifin Corporation, Sartorius AG, Eppendorf AG, Danaher Corporation, Merck KGaA, and General Electric Company.

Single-use bioprocessing system is majorly used in the upstream and downstream bioprocessing method. Moreover, key advantages offered by single-use bioprocessing such as cost reduction, increased productivity, low energy and water consumption during bioprocessing, easy disposable and reduced risk of cross contamination allows its easy and increased adoption over conventional bioprocessing systems. Moreover, government regulatory organizations are majorly adopting single-use bioprocessing systems, owing to its advantges. For instance, Australian Government: Therapeutic Goods Administration (TGA) allows the use of single-use systems in buffer preparation, mixing, and other upstream processing. Apart from this, TGA also proposed GMP regulation for filters, equipment used in single-use systems. Furthermore, increasing demand of biopharmaceuticals, growing investment on research and development activities and increasing number of key players offering affordable and technologically advanced disposable bioprocessing products are projected to drive growth of the single-use bioprocessing systems market over the forecast period.

Market Dynamics

The global single-use bioprocessing systems market is projected to witness significant growth over the forecast period, owing to its wide applications in production of monoclonal antibodies, vaccine production, and therapeutic drugs. Moreover, key players in the market are engaged in organic and in-organic growth strategies such as collaborations, strategic agreement, partnerships, mergers and acquisitions to retain competitive position in market. For instance, in April 2018, Saint-Gobain acquired the pharmaceutical business of Micro Hydraulics to strengthen its high performance material portfolio with the addition of single-use fluid handling components and systems. In August 2016, Saint-Gobain acquired Twin Bay Medical, which has added flexible tube retainers and single-use component portfolio of Twin Bay Medical into Saint-Gobain’s portfolio. In February 2015, Thermo Fisher Scientific acquired Advanced Scientifics, Inc., the provider of single-use technologies for customized bioprocessing solutions for deal value of US$ 300 million in cash. Furthermore, in November 2017, General Electric Company acquired Puridify, a bioprocessing start-up company. These acquisition help to add a nanofiber-based platform purification technology to GE Healthcare’s product portfolio. These mergers and acquisitions are expected to bring innovative single use bioprocessing systems during the forecast period.

Key features of the study:

  • This report provides in-depth analysis of the single-use bioprocessing systems market and its market size (US$ Million) and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2018 – 2026, considering 2017 as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global single-use bioprocessing systems market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies
  • Key companies covered as a part of this study include Compagnie de Saint-Gobain S.A., Thermo Fisher Scientific Inc., Applikon Biotechnology BV, Parker-Hannifin Corporation, Sartorius AG, Eppendorf AG, Danaher Corporation, Merck KGaA, and General Electric Company.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion and marketing tactics.
  • The global single-use bioprocessing systems market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors and suppliers for single-use bioprocessing systems market, research and consulting firms, new entrants and financial analysts.

Detailed Segmentation:

  • Global Single-use Bioprocessing Systems Market, By Product Type:
    • Instruments
    • Accessories
  • Global Single-use Bioprocessing Systems Market, By Application:
    • Monoclonal Antibody Production
    • Vaccine Production
    • Patient Specific Cell Therapies
    • Other Applications
  • Global Single-use Bioprocessing Systems Market, By End User:
    • Biotechnology and Pharmaceutical Companies
    • Research & Academic Research Institutes
    • Contract Research Organizations(CRO) & Contract Manufacturing Organizations(CMO)
  • Global Single-use Bioprocessing Systems Market, By Region:
    • North America Single-use Bioprocessing Systems Market
      • By Country:
        • U.S.
        • Canada
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations( CRO) & Contract Manufacturing Organizations (CMO)
    • Europe Single-use Bioprocessing Systems Market
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations (CRO) & Contract Manufacturing Organizations (CMO)
    • Asia Pacific Single-use Bioprocessing Systems Market
      • By Country:
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations (CRO) & Contract Manufacturing Organizations (CMO)
    • Latin America Single-use Bioprocessing Systems Market
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations (CRO) & Contract Manufacturing Organizations (CMO)
    • Middle East Single-use Bioprocessing Systems Market
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations (CRO) & Contract Manufacturing Organizations (CMO)
    • Africa Single-use Bioprocessing Systems Market
      • By Country:
        • North Africa
        • Central Africa
        • South Africa
      • By Product Type:
        • Instruments
        • Accessories
      • By Application:
        • Monoclonal Antibody Production
        • Vaccine Production
        • Patient Specific Cell Therapies
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Research & Academic Research Institutes
        • Contract Research Organizations (CRO) & Contract Manufacturing Organizations (CMO)
  • Company Profiles
    • Compagnie de Saint-Gobain S.A. *
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Thermo Fisher Scientific Inc.
    • Applikon Biotechnology BV
    • Parker-Hannifin Corporation
    • Sartorius AG
    • Eppendorf AG
    • Danaher Corporation
    • Merck KGaA
    • General Electric Company

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Strategic Acquisitions
    • Recent Developments
    • PEST Analysis
  4. Global Single-use Bioprocessing Systems Market, By Product Type, 2016 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Instruments
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Accessories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  5. Global Single-use Bioprocessing Systems Market, By Application, 2016 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2026 (%)
      • Y-o-Y Growth Analysis, 2016–2025
      • Segment Trends
    • Monoclonal Antibody Production
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Vaccine Production
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Patient Specific Cell Therapies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Other Applications
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  6. Global Single-use Bioprocessing Systems Market, By End User, 2016 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2026 (%)
      • Y-o-Y Growth Analysis, 2016–2025
      • Segment Trends
    • Biotechnology and Pharmaceutical Companies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Research & Academic Research Institutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Contract Research Organizations(CRO) & Contract Manufacturing Organizations(CMO)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  7. Global Single-use Bioprocessing Systems Market, By Regions, 2016 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2017 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2016 – 2025
    • North America
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • U.S.
        • Canada
    •  Europe
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    •  Africa
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • Northern Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Product Type, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2015 - 2025, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Compagnie de Saint-Gobain S.A.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Thermo Fisher Scientific Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Applikon Biotechnology BV
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Parker-Hannifin Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Sartorius AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Eppendorf AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Danaher Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Merck KGaA
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • General Electric Company
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 22 market data tables and 39 figures on "Single-use Bioprocessing Systems Market - Global forecast to 2026”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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