SNP GENOTYPING AND ANALYSIS MARKET ANALYSIS

Global SNP genotyping and analysis market is estimated to be valued at US$  20.2 Billion in 2023, and is expected to reach US$ 80.7 Billion by 2030 exhibiting a CAGR of 21.9% during the forecast period (2023-2030).

Analysts’ Views on Global SNP Genotyping And Analysis Market

Global SNP (Single-nucleotide polymorphism) genotyping market growth is supported by the launch of new products by key market players. For instance, in September 2020, NRGene, a global leader in AI-based genomic analysis for research and agricultural breeding, announced the debut of SNPer, a new tool that optimises genotyping processes and collects more data while reducing genotyping costs by up to 70%. SNPer allows the design of a customised SNP set for a specific breeding effort in order to maximise genetic information while utilising the minimum number of DNA data points.

Figure 1. Global SNP Genotyping And Analysis Market Share (%), By Technology, 2023

Global SNP Genotyping And Analysis Market– Drivers

The growing demand for precision medicine

Genetic testing is regarded as a cornerstone of the precision medicine paradigm. SNP genotyping has been demonstrated to provide insights into a variety of important issues, including therapy selection and drug responsiveness. According to a research published in the National Institutes of Health, in March 2022, the National Institutes of Health's, ‘All of Us’ Research Program made 100,000 highly varied whole genome sequences available. Approximately half of the data comes from people who identify with racial or ethnic groups that have traditionally been underrepresented in study. This information will help researchers better understand how genes cause or influence diseases in the context of other health variables, allowing for more accurate approaches to health care for all populations.

Advancement in agricultural biotechnology

According to a Fronties article published on January 10, 2023, recent breakthroughs in Next Generation (NGS) technology have revolutionised the pace and precision of plant genomics, giving low-cost genotyping platforms that allow SNPs to be employed more easily. GBS is an NGS-based SNP detection technology used to detect genome-wide SNPs and conduct genotyping studies. Regardless of prior knowledge of genetic information, genome size, or ploidy information, GBS technology gives high data volumes to a variety of agronomically important crops at a low cost per data point. SNP genotyping and analysis, in conjunction with precise sample tracking, collection, and DNA extraction, is a powerful tool for reshaping breeding programs and increasing selection gain. SNP gentotyping can help in increasing the farm yield thus, supporting the development of the market over the forecasted period.

Figure 2. Global SNP Genotyping And Analysis Market Share (%), By Region, 2023

Global SNP Genotyping And Analysis Market- Regional Analysis

Among region, North America is estimated to hold a dominant position in the global SNP genotyping and analysis market over the forecast period. North America holds 35.2% of the market share, attributed to the increading burdern of chronic disorder. Genotyping techniques can be utilized for early diagnosis and treatment of chronic diseases. According to the 2022 report from the National Association of Chronic Disease Directors, about 60% of adult Americans have at least one chronic disease. Diabetes, cancer, and cardiovascular disease are among the top causes of death in the United States. One or more of the following five chronic diseases account for more than two-thirds of all deaths: heart disease, cancer, stroke, chronic obstructive pulmonary disease, and diabetes. According to the CDC, people with chronic diseases and mental health disorders account for 90% of the nation's US$ 3.8 trillion in annual healthcare costs.

Global SNP Genotyping And Analysis Market– Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.

COVID-19 affected the economy in three main ways: by directly affecting the production and demand of SNP genotyping and analysis, by creating disruptions in supply chains, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, the U.A.E., Egypt, and others faced problems regarding transportation of materials from one place to another.

The SNP genotyping can be utilized to detect the SARS-CoV-2 variants thus, supporting the development of the market by quelling the next possible outbreak of the virus. A study published in the journal PLOS ONE, in February 2021, found that genotyping PCR allele competitive extension- reverse transcription (PACE-RT) with a narrow panel of SNPs can add useful genotype information to PCR-positive samples at a low cost. The benefit of PACE-RT SNP genotyping technique is that the SNP panel can be updated on a regular basis at a low cost. With the emergence of numerous COVID-19 variations, the PACE-RT SNP genotyping technique may be valuable for epidemiological surveillance.

Global SNP Genotyping And Analysis Market - Segmentation

Global SNP Genotyping And Analysis Market  is segmented into Technology, Applications, and Region

Based on Technology, the market is segmented into powered Polymerase Chain Reaction (PCR), Microarray, Next-Generation Sequencing (NGS), Taqman Allelic Discrimination, Pyrosequencing, and Others. Out of which, the microarray segment is expected to lead the growth of the global SNP genotyping and analysis market throughout the projected period, attributed to excellent accuracy rates, and have applications in biomarker discovery and validation, Genome-Wide Association Studies (GWAS), pharmacogenomics, clinical testing, forensics, and breed discrimination.

Based on Applications, the market is segmented into Diagnostics & Forensics, Pharmacogenomics, Agricultural Biotechnology, and Breeding & Animal Livestock. Out of which, the pharmacogenomics segment is anticipated to have the highest share of the global SNP genotyping and analysis market over the analysis period, attributed to the growing demand for precision medicine as SNP genotyping can be utilized to the effect of certain genes on drug response

Based on Region, the market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Out of which, the North America segment is anticipated to register the highest market share over the analysis period, owing to new product launches by key market players and rise in the healthcare expenditure.

Among all segmentation, the agricultural biotechnology segment has the highest potential due to increase in the number of research studies.

Global SNP Genotyping And Analysis Market- Cross Sectional Analysis

Among application, diagnostics & forensics segment is anticipated to hold a dominant position in North America region. Key market players in this region are adopting organic growth strategies such as new product launches thus, supporting the development of the market in this region. For instance, in March 2021, Thermo Fisher Scientific, a provider of medical equipment, analytical instruments, reagents and consumables, and software, announced the availability of its Applied Biosystems TaqMan SARS-CoV-2 Mutation Panel, which includes a customizable menu of 22 verified real-time PCR assays for identifying SARS-CoV-2 mutations. These assays allow scientists to choose which mutations to study and enable surveillance of variants causing COVID-19 infections in specific regions around the globe.

Global SNP Genotyping And Analysis Market- Key Developments

In August 13, 2021, Thermo Fisher Scientific, the world leader in serving science, announced it has updated its Applied Biosystems TaqMan SARS-CoV-2 Mutation Panel to detect the Delta and Lambda strains. First launched in March 2021, the research panel features a customizable menu of verified real-time PCR assays for identification of SARS-CoV-2 mutations. The panel enables laboratories to track known mutations by selecting from a menu of over 50 assays designed to screen for different variants.

Global SNP Genotyping And Analysis Market: Key Trends

Usage Of Novel Technologies For Increasing The Crop Yield

Introdcution of novel technologies for increasing the crop yield is anticipated to create lucrative opportunities for market players over the forecasted period. For instance, a report published by the Government of India, discovered that rice pan-genome genotyping array (RPGA), a 90K SNP genotyping array based on 3K rice pan-genome, has been developed for genomics-assisted breeding and accelerated agricultural improvement. Unlike conventional SNP genotyping arrays, which rely on a single reference genome, RPGA analyses variations from the whole 3K rice pan-genome. RPGA's utility for large-scale pan-genome-based genotyping applications was established by its high-throughput genotyping in rice natural germplasm accessions and recombinant inbred lines (RIL) mapping population.

Global SNP Genotyping And Analysis Market: Restraint

Limitations on sensitivity of SNP arrays

Low sensitivity of some SNP arrays can hamper the market development over the forecasted period. According to a study published in Curret Protocols in November 2022, SNP arrays can be used to detect triplication, mosaicism, and homozygous loss (nullisomy). However, SNP arrays cannot detect balanced translocations within a genome, nor can they recognise the presence of numerous clones with differing abnormalities. Furthermore, single-nucleotide variations are undetected by SNP arrays and require alternative detection approaches, such as sequencing-based methods.

Market players can develop novel sensitive SNP genotyping technologies that can utilized in different applications to increase the output.

Global SNP Genotyping And Analysis Market- Key Players

Major players operating in the global SNP genotyping and analysis market are Agilent Technologies Inc., F. Hoffmann-La Roche Ltd, Nucleome Informatics Private Limited, Azenta Life Sciences, Bio-Rad Laboratories Inc., Danaher Corporation, Douglas Scientific LLC, AllGenetics & Biology SL, Illumina Inc., Life Technologies Corp., Consultative Group on International Agricultural Research, Avance Biosciences, Genotypic Technology Pvt Ltd, Xelect Ltd, Taconic Biosciences, Inc., Luminex Corp., Promega Corporation, CD Genomics, Synbio Technologies, Thermo Fischer Scientific Inc., Sequenom, PREMIER Biosoft, Fluidigm Corporation, Novacyt, Twist Bioscience, Regeneron Pharmaceuticals, Inc, NRGene, and LGC Biosearch Technologies, among other prominent players

*Definition: Techniques for analysing genomic sequence variants are known as SNP genotyping. Real-time PCR, microarrays, and next-generation sequencing (NGS) techniques are commonly used to detect single-base alterations.