Next Generation Sequencing Market, by Technology (Whole Genome Sequencing, Whole Exome Sequencing, RNA Sequencing, Targeted Re-sequencing and Others), by Application (Drug Discovery, Personalized Medicine and Genetic Screening, Disease Diagnosis, Agriculture and Animal Research and Others), by End User (Hospital, Research Centers, Pharma and Biotech Firms and Others), and by Region - Global Industry Insights, and Forecast to 2025

  • Published On : Apr 2018 |
  • Pages : 178 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Next Generation Sequencing Market – Sequencing Made Easy

Next Generation Sequencing (NGS) is a powerful, flexible, and indispensable biological tool that is used in several areas of biological study. NGS technologies help in generating genome-wide sequence data in a couple of days. These technologies are highly parallelized allowing to sequence thousands to millions of molecules at the same time. The main advantage of these platforms is determination of the sequenced data from amplified single DNA fragments, avoiding the need for cloning of DNA fragments.

NGS has large number of applications, enabling rapid technological advances across several fields in biological science. The technology has enabled researchers to gain significant knowledge in public health studies and epidemiology, to sequence viruses and bacteria and help detect causes that may contribute to virulence. Furthermore, in gene expression research, next generation sequencing of RNA replace microarray analysis, allowing researchers to see RNA expression sequence. This RNA sequencing can provide information on entire transcriptome in one analysis, irrespective of any previous knowledge of genetic sequence.

The global next generation sequencing market was valued at US$ 5.6 billion in 2017 and is expected to witness a robust CAGR of 18.1% over the forecast period (2017–2025).

Figure 1. Global Next Generation Sequencing Market Value (US$ Bn), by Region, 2017

next generation sequencing market

Source: Coherent Market Insights (2018)

Rising demand for early detection of cancer and infectious diseases to drive growth of the NGS market

The chances of successful treatment increase when cancer and infectious diseases are detected at the early stage. One of the major factors that drive growth of the next generation sequencing market is the rising prevalence of cancer and other infectious diseases. According to the World Health Organization (WHO), in 2012, new cases of cancer was around 14 million and the incidence is estimated to increase to 70% by 2030.

As per statistics published by National Cancer Institute (NCI), in 2016, 1,685,210 new cases of cancer were diagnosed in the U.S. alone. In 2015, WHO reported 8.8 million deaths occurred due to cancer. According to American Cancer Society (ACS), in 2017, around 161,360 cases of prostate cancer were reported in the U.S alone. ACS, in 2015, also reported 4.5 million new cancer cases in China and the number is expected to increase to 7.6 Mn by 2020. Morbidity cases in tuberculosis, salmonella, and meningococcal disease was as high as 90,000 in the U.S. in 2016. Therefore, increasing demand for early diagnosis of cancer and infectious diseases, to aid in better outcome, is in turn expected to aid in growth of the market over the forecast period.

Increasing demand for DNA testing

Demand for DNA testing is increasing, due to advancements in whole genome and exome sequencing procedures, faster results and cost effectives of the process as compared to genotyping based DNA microarray. In December, 2014, the first commercial sequencer, MinIon, using Nanopore technology was introduced by Oxford Nanopore Technologies. The sequencer identifies DNA by measuring the changes in the electrical conductivity generated DNA strands passed through biological pore. This technology enabled the detection of outbreaks such as Zika virus. Furthermore, GenapSys, a U.S.-based developer of DNA sequencing technologies for applied genomic testing, introduced GENIUS sequencer, which can sequence DNA anywhere.

Key players in the next generation sequencing market include Thermo Fisher Scientific Inc., Agilent Technologies, Inc., BioMerieux S.A., F. Hoffmann-La Roche Ltd, Qiagen N.V., Illumina, Inc., Oxford Nanopore Technologies, and Beijing Genomics Co. Ltd.

Next Generation Sequencing (NGS) is a high-throughput DNA sequencing technology that separates billions or millions of DNA strands and sequence in parallel, yielding more output and reducing the need for fragment-cloning methods (Sanger sequencing of genomes). However, read lengths for NGS are shorter than Sanger due to the signal to noise ratio, which increases with read length. NGS allows simultaneous screening of mutations in large number of genes. For example, a patient with symptoms of Leigh syndrome performed exome sequencing to find candidate gene variants. Furthermore, it is used for analysis and for interpreting sequenced data, analyzing specific gene associated with the patient’s clinical condition.

Market Dynamics

Major factors driving growth of the next generation sequencing market are early detection of cancer and infectious diseases and increasing partnership among academic and industry partnerships for research and development. For academic institutions, these collaborations help in commercialization of their discoveries from basic research to medical products. For instance, in March, 2018, Cofactor Genomics, a U.S.-based developer of Cofactor Paragon (RNA analysis tool) signed agreement with National Cancer Institute, and other three other pharma and academic institutes to show clinical ability of its product.

Increasing prevalence of cancer and infectious diseases and ability of NGS platforms to detect cancers and infectious diseases are expected to drive growth of the next generation sequencing market during the forecast period. The use of NSG for study of cancer cells mutations is increasing and the implementation of this technology has considerably aided in early diagnosis of diseases. In the U.S., over 1.69 million new cancer cases were detected in 2016; whereas the global incidence of cancer was around 14 million new cases in 2012 and an annual 19.3 million cases are estimated by 2025. However, interpretation of complex data, lack of skilled professionals, and issues related to security of NGS data are expected to limit growth of the market.

Key features of the study:

  • This report provides in-depth analysis of next generation sequencing market and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR %) for the forecast period (2017 – 2025), considering 2016 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global next generation sequencing market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments and strategies, and future plans
  • Key companies covered as a part of this study include Thermo Fisher Scientific Inc., Agilent Technologies, Inc., BioMerieux S.A., F. Hoffmann-La Roche Ltd, Qiagen N.V., Illumina, Inc., Oxford Nanopore Technologies, and Beijing Genomics Co. Ltd.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launches, technology up-gradation, market expansion, and marketing tactics
  • The global next generation sequencing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the next generation sequencing market

Detailed Segmentation:

  • Global Next Generation Sequencing Market, By Technology:
    • Whole Genome Sequencing
    • Whole Exome Sequencing
    • RNA Sequencing
    • Targeted Re-sequencing
    • Others
  • Global Next Generation Sequencing Market, By Application:
    • Drug Discovery
    • Personalized Medicine and Genetic Screening
    • Disease Diagnosis
    • Agriculture and Animal Research
    • Others
  • Global Next Generation Sequencing Market, By End User:
    • Hospital
    • Research Centers
    • Pharma and Biotech Firms
    • Others
  • Global Next Generation Sequencing Market, By Region:
    • North America
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Technology:
        • Whole Genome Sequencing
        • Whole Exome Sequencing
        • RNA Sequencing
        • Targeted Re-sequencing
        • Others
      • By Application:
        • Drug Discovery
        • Personalized Medicine and Genetic Screening
        • Disease Diagnosis
        • Agriculture and Animal Research
        • Others
      • By End User:
        • Hospital
        • Research Centers
        • Pharma and Biotech Firms
        • Others
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Thermo Fisher Scientific Inc.*
      • Company Overview
      • Product Portfolio
      • Key Highlights
      • Financial Overview
      • Market Strategies
    • Agilent Technologies, Inc.
    • BioMerieux S.A.
    • Hoffmann-La Roche Ltd
    • Qiagen N.V.
    • Illumina, Inc.
    • Oxford Nanopore Technologies
    • Beijing Genomics Co. Ltd.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Technology
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • PEST Analysis
    • PORTER’s Five Forces Model
    • Epidemiology
    • Market Trends
    • Alliances
  4. Global Next Generation Sequencing Market, By Technology, 2015 – 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016 – 2025
      • Segment Trends
    • Whole Genome Sequencing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Whole Exome Sequencing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • RNA Sequencing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Targeted Re-sequencing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
  5. Global Next Generation Sequencing Market, By Application, 2015 – 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016 – 2025
      • Segment Trends
    • Drug Discovery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Personalized Medicine and Genetic Screening
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Disease Diagnosis
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Agriculture and Animal Research
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
  6. Global Next Generation Sequencing Market, By End User, 2015 – 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016 – 2025
      • Segment Trends
    • Hospital
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Research Centers
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Pharma and Biotech Firms
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015 – 2025, (US$ Million)
  7. Global Next Generation Sequencing Market, By Region, 2015 – 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2017 and 2025 (%)
      • Y-o-Y Growth Analysis, For Region, 2016 – 2025
      • Regional Trends
    • North America
      • Market Size and Forecast, By Technology, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Technology, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Technology, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Technology, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of APAC
    • Middle East
      • Market Size and Forecast, By Technology, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Product, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
        • South Africa
        • Central Africa
        • North Africa
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Thermo Fisher Scientific Inc.*
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Agilent Technologies, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • BioMerieux S.A.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Hoffmann-La Roche Ltd
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Qiagen N.V.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Illumina, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Oxford Nanopore Technologies
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Beijing Genomics Co. Ltd.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 50 market data tables and 25 figures on "Global Next Generation Sequencing Market - Global forecast to 2025”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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