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Tissue Engineering Market – Insights
Tissue engineering is an interdisciplinary field addressed to develop functional three-dimensional tissues combining cells, scaffolds, and bioactive molecules. This field involves scientific areas such as cell biology, chemistry, material science, molecular biology, medicine, and engineering. It can be used to develop functional constructs that can be used to reestablish, maintain or improve the condition of injured body parts or tissues.
Tissue engineering also assist in regeneration of damaged tissues by combining cells from the body with highly porous scaffold biomaterials. Scaffold biomaterials act as templates for tissue regeneration and guide the growth of new tissue. Tissue regeneration is highly beneficial for clinical management of organ therapeutics such as organ transplantation. The source of cells utilized in tissue engineering can be autologous (from the patient), allogenic (from a human donor but not immunologically identical), or xenogenic (from a different species donor).
The global tissue engineering market size was valued at US$ 5.5 billion in 2017, and is expected to witness a CAGR of 11.5% over the forecast period (2018 – 2026).
Global Tissue Engineering Market Value (US$ Bn) Analysis, By Material Type, 2017
Source: Coherent Market Insights Analysis (2018)
Increasing prevalence of kidney related disorders is expected to drive the tissue engineering market growth
Tissue engineering is gaining traction in various areas such as wound care, burn treatment, orthopedics, neurology, urological products, and others. Tissue engineering can play an important role in the management of pediatric patients. Tissue or organs absent at the time of birth, in congenital anomalies such as bladder exstrophy, esophageal atresia, and congenital diaphragmatic hernia pose a serious challenges in surgical repair. Moreover, increasing burn and trauma related injuries are expected to drive the global tissue engineering market growth. According to the American Burn Association 2014 data, nearly 450,000 patients receive hospital and emergency room treatment for burns annually.
Shortage of donor for various transplantation procedures presents a severe challenge to clinicians worldwide. According to the U.S. government information on organ donation and transplantation, as of 2017 nearly 114,687 people in the U.S. were on waiting lists for transplants of kidneys, hearts, livers, and other organs. Tissue engineering can fulfil the inadequacy of organ transplantation and increasing 3D printing prominence in medical applications for regeneration is anticipated to propel the demand for tissue engineering during the forecast period. Tissue engineering also holds a promising future for the restoration of 3D contour as well as the loss of function for the affected body parts.
Tissue Engineering Market Restraints
Currently available tissue engineering methods face several problems including ineffective cell growth, insufficient, and unstable production of growth factors to stimulate cell communication and proper response and lack of suitable biomaterials and techniques for capturing appropriate physiological architectures. Moreover, inability to control cellular functions and their various properties (biological, mechanical, electrochemical and others) and issues of biomolecular detection and biosensors are other limitations associated with tissue engineering.
Furthermore, despite the growing interest in tissue engineering research, progress has been hampered by ethical and legislative debates. For instance, the ethical, political, and religious opposition for embryonic stem cell research, which primarily uses discarded non-transferred human embryos for their derivation, have biased research toward adult stem cells and severely restricted federal funding in the U.S.
Tissue Engineering Market - Regional Insights
On the basis of region, the global tissue engineering market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to foresee significant growth by 2026, owing to increasing geriatric population and research studies in the field of tissue engineering. For instance, in August 2018, bioengineers at the Pennsylvania State University developed a composite ink to 3-D print porous, bone-like constructs. The materials showed biologically favorable interactions in the laboratory, followed by positive outcomes of bone regeneration in an animal model in vivo.
Europe tissue engineering market is expected to grow at lucrative rate, owing to presence of various public and private organizations focusing on research in tissue engineering field. For instance, in UK, most tissue engineering research takes place in universities and much of the funding comes from organizations supporting the development of bioengineered organs for drug testing, including the Refinement and Reduction of Animals in Research (NC3Rs) National Centre for the Replacement and the EU’s Innovative Medicines Initiative.
Global Tissue Engineering Market Share (%), By Region, 2017
Source: Coherent Market Insights Analysis (2018)
Tissue Engineering Market - Competitive Landscape
Key players operating in the global tissue engineering market include Acelity L.P. Inc., Allergan Plc., Athersys, Inc., B. Braun, BioMimetic Therapeutics, Bio Tissue Technologies, C. R. Bard, International Stem Cell, Integra Lifesciences, Medtronic, Inc., Organogenesis Inc., Osiris Therapeutics, RTI surgical, Inc., Stryker Corporation, Tissue Regenix Group Plc., and Zimmer Biomet.
Tissue engineering is a scientific field majorly focused on the development of tissue and organ substitutes by controlling biophysical, biological, and/or biomechanical parameters in the laboratory. Tissue engineering has emerged as a rapidly expanding approach to address shortage of organs in transplantation procedures and is a major component of regenerative medicine. The general principles of tissue engineering involve combining living cells with a synthetic or natural support or scaffold to build a three dimensional living construct that is structurally, functionally, and mechanically equal to or better than the tissue that is to be replaced.
Market Dynamics
Scientific advancements in the fields of cell and molecular biology, genetics, biochemistry, biomedical engineering and materials science have opened new growth opportunities in the field of tissue engineering. Rising need for effective regenerative treatments due to the rapidly aging population coupled with increasing population suffering from diseases such as cancer, diabetes, and obesity and growth in burn and trauma cases are expected to drive the tissue engineering market growth during the forecast period. According to the World Health Organization (WHO), global diabetic population is expected to reach 336 million by 2030, from 270 million in 2015.
However, tissue engineering processes used for development of complex tissues or organs, such as heart, is facing challenges such as dearth of cell sources, biomaterials, vascularization of engineered tissues, and design of drug delivery systems. Moreover, harvesting autografts is painful, expensive, constrained by anatomical limitations and donor-site morbidity due to hematoma and infection, which is hindering growth of the market.
Key features of the study:
Detailed Segmentation:
“*” marked represents similar segmentation in other categories in the respective section.
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