Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

Meibomian gland dysfunction is a cause of dry eye syndrome (DES), also known as keratisis sicca and keratoconjunctivitis sicca. Patients with DES suffer damage to the ocular surface, instability in the tear film, and visual disturbance. Tear film covers the ocular surface, which is made up of three intertwined layers, a superficial lipid layer, produced by meibomian glands, which assists in reducing tear evaporation and uniform tear spreading, middle thick aqueous layer produced from lacrimal glands, and the innermost hydrophilic mucin layer produced from goblet cells of conjunctiva and epithelium of ocular surface.

The U.S. meibomian gland dysfunction market is estimated to be valued at US$ 1,976.6 million in 2020 and is expected to exhibit a CAGR of 15.4% during the forecast period (2020-2030).

Figure 1. U.S. Meibomian Gland Dysfunction Market Share (%) by Drug Type, 2020

U.S. Meibomian Gland Dysfunction  | Coherent Market Insights

The increasing prevalence of meibomian gland dysfunction syndrome is expected to drive the market growth during the forecast period.

According to the Fellow of the American College of Surgeons, meibomian gland disease (also referred as evaporative dry eye), is one of the most common causes of dry eyes across the globe. An estimated 50 to 70% of the elderly population has some degree of dry eye and nearly 70% of dry eye involves at least some degree of meibomian gland disease.

According to a study published by the American Optometric Association in 2017, more than 16 million Americans, including twice as many women than men, were suffering from dry eye disease, and out of them around 70% of patients had meibomian gland disease.

Furthermore, certain medications such as antihistamines, antidepressants, decongestants, and blood pressure medications can reduce tear production leading to dry eye symptoms which cause meibomian gland dysfunction.

Figure 2. U.S. Meibomian Gland Dysfunction Market Share (%), by Distribution Channel, 2020

U.S. Meibomian Gland Dysfunction  | Coherent Market Insights

The increasing excess usage of computers and mobile screens is expected to increase the incidence of meibomian gland dysfunction over the period of time

People who frequently use computers or video screens are at high risk of developing meibomian gland dysfunction, as using screens for a long duration can lead to reduced blinking and tears production. Digital device usage has increased significantly in recent years among all age groups, due to extensive use for social and professional purposes.

Blue light emitted by digital screens can lead to symptoms of dry eyes which cause meibomian gland dysfunction. Exposure to blue light (range of 400–500 nm) can be harmful to the retina. Longer duration and less intense light exposure can also induce photochemical damage in the eyes.

Furthermore, lack of sleep and excessive stress can play a crucial role in the onset of dry eye syndrome due to oily tear gland dysfunction.

According to the Centers for Disease Control and Prevention’s 2017 report, over 40 million American workers get less than six hours of sleep per night.

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U.S. Meibomian Gland Dysfunction Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2019: US$ 1,976.6 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2030
Forecast Period 2020 to 2027 CAGR: 15.4% 2030 Value Projection: US$ 8,292.0 Mn
Geographies covered:
  • U.S.
Segments covered:
  • By Drug Type: Cyclosporine, Omega-3 supplements, Antibacterial eye drops, Steroids, AZR MD 001, TP 03, NOV03 (Novatears), HY02 - Minocycline.
  • By Route of Administration: Oral, Topical.
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.
Companies covered:

Pfizer, Inc., AbbVie Inc., Johnson and Johnson Vision Care Inc., Bausch Health Companies Inc., Novartis AG, Santen Pharmaceutical Co., Ltd., I-MED Pharma Inc., OASIS Medical, Sentiss Pharma Pvt. Ltd., RegeneRx, and Akorn, Inc.

Growth Drivers:
  • The increasing prevalence of meibomian gland dysfunction syndrome
  • Excessive usage of computer and mobile screens
  • Product launches
Restraints & Challenges:
  • Potential side effects of drugs used in the treatment of meibomian gland dysfunction syndrome
  • Difficulty in diseases diagnosis

U.S. Meibomian Gland Dysfunction Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries around the globe with the World Health Organization declaring it a public health emergency. According to the World Health Organization’s report, the manifestation of coronavirus (COVID-19) has resulted in more than 6.61 million infected individuals in the U.S. as of 16 September 2020. COVID-19 can affect the economy in three main ways; by directly affecting production and demand, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. In the U.S., according to the latest update of Economic Times, there has been a plunge in consumer spending as people stayed home and avoided shopping, traveling or gathering in crowds and caused the economy to sink at an estimated annual rate of 32% in the April-June 2020 quarter.

Furthermore, players operating in the U.S. meibomian gland dysfunction market are facing major challenges on various fronts due to the COVID-19 pandemic. The major challenges include supply of raw materials for manufacturing drug formulations due to irregularities in transportation facility. Moreover, distributors of drug products are experiencing irregular demand from the retailers.

U.S. Meibomian Gland Dysfunction Market: Restraints

Potential side effects of drugs, such as steroids, used in the treatment of meibomian gland dysfunction syndrome have a wide range of side effects on the body of the patient who is continuously taking more than the prescribed dose of steroids for a longer period of time. This is expected to restrain the market growth during the forecast period.

Difficulty in disease diagnosis is also expected to hamper the market growth during the forecast period. Since, there is no single test for the diagnosis of meibomian gland dysfunction, clinicians use slit lamp findings such as lid observations, tear meniscus height, and corneal staining for assessment of this disease. Many other tests such as tear film osmolarity, inflammatory markers, and conjunctival staining are not widely used as these are expensive and take longer time. Moreover, there is a discrepancy among signs and symptoms and results of various tests for meibomian gland dysfunction as they do not correlate with each other. This variability can create confusion among patients and healthcare providers about the best course of treatment.

Key Players

Major players operating in the U.S. meibomian gland dysfunction market are Pfizer, Inc., AbbVie Inc., Johnson and Johnson Vision Care Inc., Bausch Health Companies Inc., Novartis AG, Santen Pharmaceutical Co., Ltd., I-MED Pharma Inc., OASIS Medical, Sentiss Pharma Pvt. Ltd., RegeneRx, and Akorn, Inc.

Meibomian gland dysfunction (MGD) is a term used to describe a group of disorders, both congenital and acquired. Disruption of meibomian gland function negatively impacts both the quality and quantity of meibum secreted, which in turn affects ocular surface health through changes in tear film composition. Increased tear evaporation, hyperosmolarity, inflammation, and ocular surface damage can subsequently occur and cause discomfort, visual disruption, and sensation of dry eyes.

Market Dynamics

There are various late-stage pipeline drugs for dry eye associated meibomian gland dysfunction syndrome treatment such as RegeneRx’s RGN-259, which is expected to be the strongest pipeline asset for the meibomian gland dysfunction syndrome treatment market. For instance, in April 2018, RegeneRx Biopharmaceuticals, inc. announced the outcome of discussions between its U.S. joint venture, ReGenTree LLC, and the FDA regarding the results of the completed phase 3 clinical trial (ARISE-2) and the future development requirements for a New Drug Application (NDA) submission of RGN-259, a novel drug candidate to treat dry eye syndrome associated meibomian gland dysfunction syndrome.

Key features of the study:

  • This report provides in-depth analysis of the U.S. meibomian gland dysfunction market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2020–2030), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the U.S. meibomian gland dysfunction market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include Pfizer, inc., AbbVie Inc., Johnson and Johnson Vision Care Inc., Bausch Health Companies Inc., Novartis AG, Santen Pharmaceutical Co., Ltd., I-MED Pharma Inc., OASIS Medical, Sentiss Pharma Pvt. Ltd., RegeneRx, and Akorn, inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The U.S. meibomian gland dysfunction market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the U.S. meibomian gland dysfunction market

Detailed Segmentation:

  • U.S. Meibomian Gland Dysfunction Market, By Drug Type:
    • Cyclosporine
    • Omega-3 supplements
    • Antibacterial Eye Drops
    • Steroids
    • AZR MD 001
    • TP 03
    • NOV03 (Novatears)
    • HY02 – Minocycline
  • U.S. Meibomian Gland Dysfunction Market, By Route of Administration:
    • Oral
    • Topical
  • U.S. Meibomian Gland Dysfunction Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Company Profiles
    • Pfizer, Inc. *
      • Company Overview
      • Material Portfolio
      • Financial Performance
      • Key Highlights
      • Market Strategies
    • AbbVie Inc.
    • Johnson and Johnson Vision Care Inc.
    • Bausch Health Companies Inc.
    • Novartis AG
    • Santen Pharmaceutical Co., Ltd.
    • I-MED Pharma Inc.
    • OASIS Medical
    • Sentiss Pharma Pvt. Ltd.
    • RegeneRx
    • Akorn, Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Drug Type
      • Market Snippet, By Route of Administration
      • Market Snippet, By Distribution Channel
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Regulatory Scenario
    • PEST Analysis
    • Emerging Strategies for the Diagnosis and Treatment of Meibomian Gland Dysfunction
    • Mechanical Treatment for Meibomian Gland Dysfunction
    • Diquafosol (Diquas) Projected Sales (Marketed Only in Asia)
    • Epidemiology
    • Pipeline Analysis
    • Product Launch
    • Acquisition, Collaboration and Agreements
    • Reimbursement Scenario
  4. U.S. Meibomian Gland Dysfunction Market – Impact of Coronavirus (COVID-19) Pandemic
    • Economic Impact
    • Government Initiative
    • Clinical Trial Analysis
  5. U.S. Meibomian Gland Dysfunction Market, By Drug Type, 2016 – 2030, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2030 (%)
      • Y-o-Y Growth Analysis, 2017 – 2030
      • Segment Trends
    • Cyclosporine
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Omega-3 supplements
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Antibacterial Eye Drops
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Steroids
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • AZR MD 001
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • TP 03
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • NOV03 (Novotears)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • HY02 - Minocyline
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
  6. U.S. Meibomian Gland Dysfunction Market, By Route of Administration, 2016 – 2030, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2030 (%)
      • Y-o-Y Growth Analysis, 2017 – 2030
      • Segment Trends
    • Oral
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Topical
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
  7. U.S. Meibomian Gland Dysfunction Market, By Distribution Channel, 2016 – 2030, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2030 (%)
      • Y-o-Y Growth Analysis, 2017 – 2030
      • Segment Trends
    • Hospital Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Retail Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
    • Online Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
  8. Competitive Landscape
    • Heat Map Analysis
    • Market Share Analysis
      • Pfizer, Inc. *
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • AbbVie Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Johnson and Johnson Vision Care Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Bausch Health Companies Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Novartis AG
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Santen Pharmaceutical Co., Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • I-MED Pharma Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • OASIS Medical
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Sentiss Pharma Pvt. Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • RegeneRx
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Akorn, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 9 market data tables and 21 figures on "Meibomian Gland Dysfunction Market” - U.S. forecast to 2030

Frequently Asked Questions

The U.S. meibomian gland dysfunction market size is estimated to be valued at US$ 1,976.6 million in 2020 and is expected to exhibit a CAGR of 15.4% between 2020 and 2030.
Factors such as the increasing prevalence of meibomian gland dysfunction syndrome, excessive usage of computers and mobile screens, and novel product launches are expected to drive the market growth during the forecast period.
Cyclosporine segment is expected to hold the major market share, owing to increasing product approvals and launches during the forecast period.
Major factors hampering growth of the market include potential side effects of drugs used in the treatment of meibomian gland dysfunction syndrome and difficulty in diseases diagnosis.
Major players operating in the U.S. meibomian gland dysfunction market are Pfizer, Inc., AbbVie Inc., Johnson and Johnson Vision Care Inc., Bausch Health Companies Inc., Novartis AG, Santen Pharmaceutical Co., Ltd., I-MED Pharma Inc., OASIS Medical, Sentiss Pharma Pvt. Ltd., RegeneRx, and Akorn, Inc.
An estimated 50 to 70% of the elderly population has some degree of dry eye and nearly 70% of dry eye involves at least some degree of meibomian gland disease.
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