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Viscosupplementation Market Analysis & Forecast: 2025-2032

Viscosupplementation Market, By Dosage (Single Injection, Three Injection, and Five Injection), By Arthritis Type (Osteoarthritis and Rheumatoid Arthritis), By End User (Hospitals, Specialty Clinics, Ambulatory Surgical Centers, and Others), By Geography (North America, Latin America, Europe, Asia Pacific, Middle East & Africa)

  • Published In : 10 Oct, 2025
  • Code : CMI197
  • Pages :160
  • Formats :
      Excel and PDF
  • Industry : Pharmaceutical
  • Historical Range: 2020 - 2024
  • Forecast Period: 2025 - 2032

Global Viscosupplementation Market Size and Share Analysis  

The viscosupplementation market is estimated to be valued at USD 4.15 Bn in 2025 and is expected to reach USD 7.11 Bn by 2032, growing at a compound annual growth rate (CAGR) of 8% from 2025 to 2032.

Viscosupplementation Market Key Factors

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Key Takeaways

  • Based on End User, Hospitals Segment contributes the highest share of the viscosupplementation market and is projected to hold 48.7% of the market share in 2025. This is because many patients rely on hospitals for more involved treatment plans that integrate viscosupplementation alongside comprehensive arthritis management.
  • By Dosage Type, Three Injection Segment is poised to hold about 46.3% shares in the global market in 2025.
  • Based on Arthritis Type, Osteoarthritis Contributes the highest share of the viscosupplementation market and is projected to hold 68.3% of the market share in 2025.
  • North America dominant regional market for viscosupplementation and is expected to hold 48.3% of the market share in 2025. With a strong presence of leading medical device manufacturers and favorable reimbursement policies for knee osteoarthritis treatments, the U.S. accounts for the major share in the regional market.

Market Overview

The global viscosupplementation market is witnessing steady growth, led by the growing incidence of osteoarthritis and demand for less invasive, pain-relieving treatments. The aging population, especially in mature and emerging economies, continues to propel demand for intra-articular hyaluronic acid injections that improve joint mobility, alleviate pain, and postpone joint replacement surgery. Growing uses in outpatient orthopedic treatment and sports medicine are also driving the market momentum.

Current Events and Its Impact on the Viscosupplementation Market

Current Events

Description and its impact

 

Push Towards Green Hyaluronic Acid Production

 

  • Description:  Description: In 2024, viscosupplementation market leaders such as Seikagaku Corporation, Anika Therapeutics, and LG Chem enhanced efforts to manufacture eco-friendly, non-animal-sourced hyaluronic acid (HA). Through the use of microbial fermentation technology instead of rooster comb harvesting, the companies are reducing environmental impact and responding to rising ethical and sustainability demands. Attempts have increased to apply recyclable packaging and reduce manufacturing emissions to meet international standards of sustainability, particularly in Europe and North America.
  •   Impact: This change helps pharmaceutical organizations meet ESG (Environmental, Social, Governance) objectives and is particularly attractive to healthcare suppliers subject to green procurement requirements. Rapid take-up in the EU has been fueled by rising compliance with tighter REACH and environmental labeling regulations. Sustainable production of HA remains 15–20% more expensive, though, which will potentially slow uptake in cost-conscious areas like parts of Southeast Asia or Latin America. Nonetheless, the long-term trend favors green innovation, with increased funding for sustainable biotech research expected.

 

Integration of AI Diagnostics and Smart Injection Systems

 

  • Description:  Zimmer Biomet and Chugai Pharmaceutical introduced AI-powered diagnostic platforms and precision-enabled injection devices in 2024 to optimize patient selection and delivery accuracy of viscosupplementation treatments. The devices utilize real-time imaging, predictive analytics, and robotics to minimize human error and optimize injection depth and placement, optimizing treatment outcomes while meeting digital health goals.
  • Impact: These technologies are picking up pace in North America, Japan, and South Korea where smart investments in healthcare and AI implementation are gaining speed. Specialty clinics and hospitals are seeing 25–35% savings in treatment failure and repeat injections, enhancing cost savings and patient satisfaction. Initial investment in AI systems continues to be a barrier for small public hospitals and clinics in lower-income nations. In due course, with costs reducing and regulatory systems in place to ensure adjustment, smart viscosupplementation systems will become the norm in precision joint therapy.

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Market Concentration and Competitive Landscape

Viscosupplementation Market Concentration By Players

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Market Dynamics

Market Driver

Since the global population is ageing greatly, elderly individuals with a risk of mobility issues and joint disorders are growing at a tremendous rate. Osteoarthritis is one of the leading causes of disability in the elderly population globally. It most often affects the hands, hips, and knees and can render even simple movements painfully difficult. Since people are living longer as a result of advancements in healthcare and nutrition, osteoarthritis has reached epidemic proportion.

Increasing numbers of older adults are driving the need for effective osteoarthritis treatment and pain relief. Viscosupplementation procedures cushion and lubricate osteoarthritic joints, facilitating movement while minimizing pain. They enable most older patients to forgo joint replacement surgery or other surgery, enhancing their quality of life.

Increased awareness and utilization of non-surgical options

International Internet and support group spread of health information has increased awareness about a range of non-surgical osteoarthritis options. Conservative treatment options to joint replacement, at least in the earlier stages of the disease, are increasingly being selected by patients. Viscosupplementation procedures are particularly appealing here since they are non-surgical and entail mere local injections to enrich joint fluid viscosity.

Unlike the sometimes-exuberant alternative of joint replacement, viscosupplementation permits patients to avoid complicated surgery and extended rehabilitation. It preserves the natural joint and improves mobility without extensive downtime or the risks of surgery.

Market Opportunities: Growing prevalence of osteoarthritis

With rising geriatric populations worldwide, the prevalence of osteoarthritis is increasing rapidly. This growing patient pool suffering from joint pain indicates higher demand. Furthermore, ongoing research into newer viscosupplements promises treatments that are longer-lasting or require fewer injections. Expanded health coverage through insurance plans could help boost the market by facilitating access.

Segmental Insights

Viscosupplementation Market By Dosage

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Viscosupplementation Market Insights, By Dosage

The dosage segment includes single injection, three injection, and five injections. Three injection is anticipated to hold 46.3% of the market share in 2025. Completing a full treatment course in just three visits increases compliance rates compared to longer five injection regimens. Busy patients appreciate that Three Injection shortens disruption to their daily routine.

Healthcare providers also favor Three Injection, as three visits reduces the burden on resources versus single alternatives that may require additional follow up appointments due to incomplete relief of symptoms. The consistent dosing schedule of Three Injection further aids treatment adherence. Receiving regular injections on the same cadence helps patients establish a routine and stick to their care plan.

In contrast, options with varied intervals like single or five injections can confuse patients and compromise how diligently they follow prescription instructions. Overall, Three Injection strikes the right balance for most osteoarthritis sufferers seeking prompt symptom relief without excessive disruption to work and personal obligations.

Viscosupplementation market Insights, By Arthritis Type

The arthritis type segment includes osteoarthritis and rheumatoid arthritis. Osteoarthritis contributes the highest share of the viscosupplementation market and is projected to hold 68.3% of the market share in 2025. Osteoarthritis accounts for over 60% of all arthritis cases and directly affects 27 million Americans, with many more affected indirectly as caregivers. The sheer scale of the eligible patient pool makes it the dominant market segment.

Additionally, the degenerative nature of osteoarthritis often limits the effectiveness of alternatives like medication management alone. Viscosupplementation offers a minimally invasive solution preferred by both patients and providers over joint replacement in earlier disease stages.

Viscosupplementation Market Insights, By End User

The end user segment includes hospitals, specialty clinics, ambulatory surgical centers, and others. Hospitals contribute the highest share of the viscosupplementation market and is projected to hold 48.7% of the market share in 2025. As arthritis disproportionately affects the elderly, many patients rely on hospitals for more involved treatment plans that integrate viscosupplementation alongside comprehensive arthritis management.

In contrast to stand-alone clinics, hospitals offer a full spectrum of related specialists under one roof including rheumatologists, orthopedic surgeons, and physical therapists. Hospitals also boast advanced imaging technology that aids accurate assessment and monitoring of treatment progress.

Dedicated operating rooms allow hospitals to efficiently perform procedures for patients who require injections combined with arthrocentesis or joint lavage for improved distribution of supplements to targeted areas. Their round-the-clock services further accommodate patients with limited mobility or availability.

Regional Insights

Viscosupplementation Market Regional Insights

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North America Viscosupplementation Market Analysis and Trends

North America has established itself as the dominant regional market for viscosupplementation and is expected to hold 48.3% of the market share in 2025. With a strong presence of leading medical device manufacturers and favorable reimbursement policies for knee osteoarthritis treatments, the U.S. accounts for the major share in the regional market.

The growing adoption of minimally invasive procedures and rising obesity rates that increase the risk of osteoarthritis have further augmented demand over the years. Additionally, well-established distribution channels ensure easy accessibility to products across the region.

Asia Pacific Viscosupplementation Market Analysis and Trends

The viscosupplementation market in Asia Pacific has emerged as the fastest growing regional market globally. Countries like China, India, Japan, and South Korea are witnessing substantial rise in knee osteoarthritis cases driven by growing geriatric population and increasing lifestyle disease prevalence. This has boosted the uptake of viscosupplementation as an effective non-surgical treatment option.

The market is also gaining from economic development across emerging nations, growing medical tourism, and improving access to healthcare facilities. Local manufacturers are augmenting their presence to cater to the rising needs. For instance, some Chinese companies have indigenously developed cost-effective viscosupplements to tap into the domestic demand.

Viscosupplementation market dominating countries

United States Viscosupplementation Market Analysis and Trend

The United States dominates the world viscosupplementation market due to a high population with aging, high incidence of osteoarthritis, and well-developed healthcare infrastructure. The nation is also characterized by early acceptance of new treatments and established market presence of major players such as Zimmer Biomet and Sanofi.

Germany Viscosupplementation Market Analysis and Trend

Germany is the largest European market for viscosupplementation. The country's emphasis on orthopedic treatment, along with the presence of a high elderly population and government encouragement for minimally invasive surgeries, all add to the market growth.

Japan Viscosupplementation Market Analysis and Trend

Japan is a priority market within the Asia-Pacific region because of its rapidly aging population and high prevalence of knee osteoarthritis. The nation also possesses a highly developed healthcare system as well as increasing awareness of non-surgical care such as viscosupplementation.

China Viscosupplementation Market Analysis and Trend

China's viscosupplementation market is growing speedily, driven by its large population, rising incidence of osteoarthritis, and growing healthcare expenditure. Urbanization and enhanced access to healthcare services are also driving demand for non-surgical joint therapies.

Market Report Scope

Viscosupplementation Market Report Coverage

Report Coverage Details
Base Year: 2024 Market Size in 2025: USD 4.15 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 8% 2032 Value Projection: USD 7.11 Bn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Dosage: Single Injection, Three Injection, and Five Injection
  • By Arthritis Type: Osteoarthritis and Rheumatoid Arthritis
  • By End User: Hospitals, Specialty Clinics, Ambulatory Surgical Centers, and Others 
Companies covered:

Anika Therapeutics Inc., Seikagaku Corporation, Ferring Pharmaceuticals, Bioventus, Fidia Farmaceutici S.P.A., Mylan N.V., Sanofi S.A., OrthogenRx, Teva Pharmaceutical Industries Ltd, Johnson & Johnson., F. Hoffmann-La Roche AG, Zimmer Biomet, Aptissen, Wellchem Pharmaceuticals Pte Ltd., Juniper Biologics, and Ono Pharmaceutical Co., Ltd

Growth Drivers:
  • Growing elderly population and risk of osteoarthritis
  • Increased awareness and preference for non-surgical treatments 
Restraints & Challenges:
  • High cost of viscosupplementation therapies
  • Lack of reimbursement policies

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Key Developments

  • In early 2025, LG Chem rolled out its strategic entry into the Asia-Pacific market for viscosupplementation, launching a new brand of non-animal-derived hyaluronic acid injectables. It invested in local capacity in South Korea and Vietnam to address growing regional demand and to better meet local health authority requirements.
  • In October 2024, Anika Therapeutics, a joint preservation leader, unveiled the expansion of its viscosupplementation portfolio with next-generation hyaluronic acid-based injectables that are intended to provide longer-lasting relief and fewer injections. The development was aimed at improving patient outcomes in knee osteoarthritis and enhancing Anika's presence in orthopedic clinics worldwide.

Analyst View

  • The market for viscosupplementation is mainly fueled by the increasing incidence of osteoarthritis (OA) globally, especially among elderly populations, since the treatment is a surgical-free option to treat joint degeneration and pain. Growth in demand for less invasive treatments—combined with improvements in formulations of hyaluronic acid (HA)—has seen greater adoption, particularly in the treatment of knee OA.
  • But the market is threatened by uneven clinical results by patient subgroups and competition from corticosteroid injections, physical therapy regimens, and new regenerative therapies such as platelet-rich plasma. Opportunities for growth exist in broadening applications to under-treated joints like hips and small joints, in addition to creating next-generation HA products with longer efficacy durations and improved viscoelasticity.
  • Geographically, Europe and North America lead with high rates of OA diagnosis, strong reimbursement systems, and well-established healthcare infrastructure, whereas Asia-Pacific has high growth potential driven by increasing medical access and increasing obesity rates in nations such as China. Latin America is promising with Brazil being identified as a major market, led by increasing private healthcare investments. Producers are tactically targeting single-injection treatment to enhance patient compliance as well as cut treatment expenses, although three-injection programs still maintain preferential position in clinical use owing to perceived effectiveness.
  • The development of non-avian sourced HA products caters to allergy issues and further expands the pool of patient eligibility. In spite of these improvements, market penetration remains limited in lower-income nations owing to cost sensitivities and modest awareness, highlighting the necessity for targeted education campaigns and localized pricing strategies.

Market Segmentation

  • Dosage Insights (Revenue, USD Bn, 2020 - 2032)
    • Single Injection
    • Three Injection
    • Five Injection
  •  Arthritis Type Insights (Revenue, USD Bn, 2020 - 2032)
    • Osteoarthritis
    • Rheumatoid Arthritis
  •  End User Insights (Revenue, USD Bn, 2020 - 2032)
    • Hospitals
    • Specialty Clinics
    • Ambulatory Surgical Centers
    • Others
  • Regional Insights (Revenue, USD Bn, 2020 - 2032)
    • North America
      • U.S.
      • Canada
    • Latin America
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
    • Europe
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Middle East
      • GCC Countries
      • Israel
      • Rest of Middle East
    • Africa
      • South Africa
      • North Africa
      • Central Africa
  • Key Players Insights
    • Anika Therapeutics Inc.
    • Seikagaku Corporation
    • Ferring Pharmaceuticals
    • Bioventus
    • Fidia Farmaceutici S.P.A.
    • Mylan N.V.
    • Sanofi S.A.
    • OrthogenRx
    • Teva Pharmaceutical Industries Ltd.
    • Johnson & Johnson
    • F. Hoffmann-La Roche AG
    • Zimmer Biomet
    • Aptissen
    • Wellchem Pharmaceuticals Pte Ltd.
    • Juniper Biologics
    • Ono Pharmaceutical Co., Ltd.

Sources

Primary Research interviews

  • Anika Therapeutics executives
  • Zimmer Biomet product managers
  • Smith & Nephew R&D specialists
  • F. Hoffmann La Roche regulatory affairs teams
  • Others

Magazines

  • Orthopedic Design & Technology Magazine
  • Medical Product Outsourcing Magazine
  • Biopharma Trend
  • Others

Journals’

  • Osteoarthritis and Cartilage Journal
  • Journal of Bone and Joint Surgery
  • Clinical Orthopaedics and Related Research
  • Others

Newspapers

  • Business Wire press release archives
  • GlobeNewswire industry announcements
  • Reuters Health News
  • Others

Associations

  • American Academy of Orthopaedic Surgeons (AAOS)
  • Arthritis Foundation
  • International Cartilage Regeneration & Joint Preservation Society
  • Others

Public Domain sources

  • U.S. CDC osteoarthritis prevalence data
  • NIH National Institute of Arthritis reports
  • WHO Global Burden of Disease studies
  • Others

Proprietary Elements

  • CMI Data Analytics Tool
  • Proprietary CMI Existing Repository of information for last 8 years

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About Author

Vipul Patil is a dynamic management consultant with 6 years of dedicated experience in the pharmaceutical industry. Known for his analytical acumen and strategic insight, Vipul has successfully partnered with pharmaceutical companies to enhance operational efficiency, cross broader expansion, and navigate the complexities of distribution in markets with high revenue potential.

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Frequently Asked Questions

The Viscosupplementation Market size is estimated to be valued at USD 4.15 Bn in 2025, and is expected to reach USD 7.11 Bn by 2032.

The CAGR of the global Market is projected to be 8% from 2025 to 2032.

Growing elderly population and risk of osteoarthritis and increased awareness and preference for non-surgical treatments are the major factors driving the growth of the market.

High cost of viscosupplementation therapies and lack of reimbursement policies are the major factors hampering the growth of the global market.

In terms of dosage, three injection is estimated to dominate the market revenue share in 2025.

Anika Therapeutics Inc., Seikagaku Corporation, Ferring Pharmaceuticals, Bioventus, Fidia Farmaceutici S.P.A., Mylan N.V., Sanofi S.A., OrthogenRx, Teva Pharmaceutical Industries Ltd, Johnson & Johnson., F. Hoffmann-La Roche AG, Zimmer Biomet, Aptissen, Wellchem Pharmaceuticals Pte Ltd., Juniper Biologics, and Ono Pharmaceutical Co., Ltd are the major players.

North America is expected to lead the market.

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