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Faux Fasting Helps Live Longer and Healthier Life

Nov, 2021

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A new study demonstrated cycles of imitated low-calorie diet fasting can prevent obesity and heart diseases in mice increasing their life span.

Many studies have been conducted on different diets to assess their efficiency in preventing heart disease and obesity in mice and humans both. A new research conducted on mice by a group of scientists from University of Southern California showed cycles of fasting-mimicking diets with low-calorie food reduce the harmful effects of their normal high-calorie diet.

In a new USC study on the health effects of a low-calorie diet that mimics fasting in the body, researchers found regular five-day cycles of the diet in mice seemed to counteract the detrimental effects of their usual high-fat, high-calorie diet. The study, published today in Nature Metabolism, analyzed the diet, health and lifespan of three different groups of mice over two years.  

Scientists continue to explore the connection between fasting and the consequences for human health, both good and bad, and part of this research includes diets that merely mimic its effects. A new study has shown how short spurts of these so-called fasting-mimicking diets can bring about a range of benefits in otherwise unhealthy mice, ultimately preventing the buildup of fat and onset of obesity.

Fasting-mimicking diets (FMDs) are low-calorie diets that are designed to trick the body into a fasting state, and we've seen some interesting studies around the various ways they can influence health. A pair of papers from 2017 showed that FMDs in diabetic mouse models could restore insulin production and stabilize blood glucose, as well as regenerate the pancreas. Another from last year showed how FMD diets might improve chemotherapy outcomes in cancer patients.

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