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Post Vaccine COVID Infection May Create "Super Immunity"

Mar, 2022

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According to researchers, each vaccination strengthens the immune response to subsequent exposure, even to newer variants.

Researchers at the University of Oregon Health and Science have observed in a study that people who have been progressively infected after getting the Covid-19 vaccine may develop "super-immunity" to the virus. This study was published in the American Medical Association Journal. Blood samples produced two weeks post the second dose of the Pfizer vaccine were 1,000% more productive at successfully injecting infected people. As a part of this study, the 52 university employees who have got the Pfizer vaccine, were collected blood samples.

A total of 26 people was found to have mild infections after vaccination. According to the study, 10 out of those cases included highly infectious delta types, 9 non-delta types, and 7 unknown types. Senior author Dr. Fikadu Tafesse (Assistant professor of molecular microbiology at UOHS) said, “You can’t get a better immune response than this. These vaccines are very productive against severe disease.” Co-author Dr. Marcel Curlin (Associate professor of medicine in the UOHS School of Medicine) said, “I think this speaks to an eventual end game. It doesn’t mean we’re at the end of the pandemic, but it points to where we’re likely to land: Once you’re vaccinated and then exposed to the virus, you’re probably going to be reasonably well-protected from future variants.”

The team also calculated and compared the immune response to the present virus disclosed to blood taken from people with development cases and the immune response to the control group. They found the development cases induced more antibodies at baseline. As a result, those antibodies are pretty good at neutralizing the virus directly. The researchers observed that they didn’t particularly analyze the Omicron variant, but on the basis of the results of the study, it was speculated that a successful infection with this variant would produce equally strong immune reactions in vaccinated people.

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