Unlocking The Connection Between COVID-19 And Gut Diseases

Jun, 2023 - by CMI

According to a report that was published in Gut, new-onset abnormalities of the gut-brain connection should be expected after infection with COVID-19 and especially after being hospitalized for this illness.

To assess the long-term effects of COVID-19 infection on the gastrointestinal system, Italian researchers prospectively and sequentially included 883 eligible hospital patients with and without COVID-19 between May and October 2020. 

Participants who took part in the study had their health assessed upon admission to the hospital as well as one, six, and twelve months afterward. The research participants' gastrointestinal complaints, anxiety, and depressive symptoms were evaluated using questionnaires. 

The investigation comprised 614 patients with COVID-19. 269 patients who were hospitalized to the hospital for conditions other than COVID-19 made up the control group. These conditions comprised symptoms including gastroenterological, traumatic, and surgical pertinence.

The study reported in Gut suggests that following exposure to COVID-19, especially after hospitalization for sickness, one should be suspicious of newly appearing anomalies in the gut-brain axis. 

To evaluate the long-term consequences of COVID-19 infection on the gastrointestinal system, Italian researchers set out to enroll 883 qualified individuals with and without COVID-19 in the home patient register in May 2020 and October 2020. 

Participants in the study evaluated their health at enrollment and 1, 6, and 12 months afterward. A questionnaire was used to measure the individuals' levels of depression, anxiety, and depressive symptoms. 

In comparison to control patients, COVID-19 patients experienced a considerably decreased incidence of constipation and firm stools after a year. However compared to just one control patient who developed IBS at the 12-month mark, COVID-19 patients had a greater incidence of IBS at this stage. Patients in either group who had a history of allergies, persistent PPI use, or dyspnea at the time of admission had a higher likelihood of developing IBS. Their rate corresponds to the findings of a recent meta-analysis. 

The researchers discovered that the COVID-19 patient group had greater rates of both depression and anxiety than the control group did.