Warmer Ambient Temperatures and Gut Microbiota Might Prevent Osteoporosis, Study Suggests

Jan, 2021 - by CMI

According to a new research study initiated by the researchers of University of Geneva (UNIGE), Switzerland, has reported to observe that bone strength increases if there is exposure to warmer ambient temperatures (34°C), thereby exhibiting the potential to prevent osteoporosis. Moreover, researchers also reported that warm climate alters the composition of gut microbiota, which could further be replicated by resettling the microbiota of mice living in a warm environment to mice suffering from osteoporosis. This experiment was conducted on mice models and researchers observed that after the transplant, mice models exhibited stronger and denser bones. Osteoporosis can be defined as bone related disease, which is associated with aging and is characterized by a micro-architectural deterioration of the bones, loss of bone density, and high risk of fractures and also affects post-menopausal women.

Mirko Trajkovski, Professor at the Department of Cell Physiology and Metabolism and at the Diabetes Centre of the UNIGE Faculty of Medicine, stated, “In one experiment, we placed newborn mice at a temperature of 34 °C in order to minimize the heat shock associated with their birth. We found that they had longer and stronger bones, confirming that bone growth is affected by ambient temperature.” But what about adulthood?

Furthermore, researchers tried the similar experiment by involving several groups of adult mice and were kept in a warm environment, and later researchers observed that there was no change in bone size, however bone strength and density were significantly improved. Similarly, researchers also performed the experiment on mice after an ovariectomy modeling post-menauposal osteoporosis and found similar results that warming the living environment protected the mice from the bone loss typical of osteoporosis. Researchers further analyzed this co-relation on human beings and found that incidence of hip fractures was higher in northern countries, in comparison to warm southern countries.

Researchers concluded that further studies are required and these outcomes acts as an indicator that warmth could be a prevention approach against osteoporosis.