Dedifferentiated Liposarcoma Treatment Market, by Treatment Type (Chemotherapy, Immunotherapy, and Radiation Therapy), by End User (Hospitals, Multispecialty Clinics & Cancer Treatment, and Rehabilitation Centers), and by Geography - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026

  • To Be Published : Jul 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Liposarcoma refers to one of the most commonly diagnosed type of soft tissue sarcomas. It is a type of cancer that originates from the fat cells in deep tissues. On the other hand, dedifferentiated Liposarcoma is the least common subtypes among all types of sarcomas and arises from a well-differentiated sarcoma. The tumors of dedifferentiated Liposarcoma are typically present in the retroperitoneal/abdominal cavity followed by the limbs. The reason for development of these tumors are still unknown, however, genetic mutations is considered to be one of the factors in generation of these tumors. The most commonly employed treatment for dedifferentiated sarcoma includes complete excision and removal of the tumor by various therapies such as liposuction and targeted immunotherapy. Dedifferentiated Liposarcoma does not have any gender predilection, however, is commonly found in patients over the age of 50 years. The global dedifferentiated Liposarcoma treatment market is expected to exhibit a moderate growth rate, which attributes to low incidence of the disease across the globe. According to the World Health Organization 2016, the incidence rate of well-differentiated Liposarcoma accounts for 2.5 per million, wherein de-differentiated Liposarcoma accounts for 18% of the total incidence of Liposarcoma across the globe.

Market Dynamics

Rising incidence of genetic disorders is one of the major factors responsible for growth of the global dedifferentiated Liposarcoma treatment market. According to a report published by Genetics Education Center, University of Kansas Medical Center 2012, 15% of all the cancer have an inherited susceptibility as well as 12% of the hospital admissions in the U.S. accounted for treatment of genetic causes in 2013. Moreover, according to a report published by Massachusetts General Hospital in 2017, Liposarcoma affected around 375,000 people worldwide. Various other factors contributing to growth of the market include changing lifestyle and growing awareness among populace regarding availability for the treatment of Liposarcoma through various initiatives undertaken by government, non-government, and other organizations. For instance, Liposarcoma Genome Project initiative by Massachusetts General Hospital Cancer Center includes conducting research to understand the differences between well-differentiated and dedifferentiated Liposarcoma, to support in developing leading edge treatment for the rare disease. Conversely, high costs associated with treatment procedures and low accessibility due to the rareness of disease are expected to be factors hindering the market growth.

Regional Insights

On the basis of region, the global dedifferentiated Liposarcoma treatment market by Coherent Market Insights is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America holds the dominant position in the global dedifferentiated Liposarcoma treatment market, owing to increasing research and development of novel therapies and potential drugs for dedifferentiated Liposarcoma. For instance, the Sarcoma Foundation of America (SFA) aids sarcoma patients by providing funding for research to private researchers and conducts education campaigns for patients suffering from various types of sarcomas.

Furthermore, Asia Pacific market is expected to gain significant traction in the near future, owing to increasing research and development of new drugs and immunotherapies, to combat the disease as well as presence of significant population suffering from the disease in this region. For instance, according to the Journal of Blood & Lymph 2013, in India up to 35% of patients suffering with Sarcoma died due to dedifferentiated Liposarcoma, wherein the total number of deaths as a result of sarcoma was reported to be 328 patients in 2012.

Competitive Analysis

Key players operating in the global dedifferentiated Liposarcoma treatment market include Johnson & Johnson Services, Inc., Eli Lily & Company, Novartis AG, Pfizer, Inc. and Sanofi SA. Major players are focusing on innovation and development, to maintain their position in the market and enhance its share. For instance, in July 2017, Karyopharm Therapeutics, Inc. cleared Phase II clinical trial for Selinexor, an orally administered inhibitor of CRM1, to treat patients with unresectable dedifferentiated liposarcoma.

Market Taxonomy:

The chemotherapy segment is expected to be dominant, owing to widespread availability of drugs across the world. According to the British Medical Journal, the European Medical Agency approved the use of 48 cancer drugs for 68 indications in Europe. Moreover, patent expiry is leading to entrance of large number of generic players in the market, which also propels growth of chemotherapy segment. However, immunotherapy is expected to gain marginal traction in the forecast period, owing to extensive research and development associated with the implementation of targeted cell therapy and other immunotherapies that have lower side effects than the chemotherapy. According to Memorial Sloan Kettering Cancer Center 2015, checkpoint inhibitor based immunotherapy is being effectively tested against dedifferentiated Liposarcoma and has potential benefits in treating the disorder.

On the basis of treatment type, the global dedifferentiated Liposarcoma treatment market is segmented into:

  • Chemotherapy
  • Immunotherapy
  • Radiation Therapy

On the basis of end user, the global dedifferentiated Liposarcoma treatment market is segmented into:

  • Hospitals
  • Multispecialty Clinics
  • Cancer Treatment & Rehabilitation Centers

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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