Global Charcot-Marie-Tooth Disease Market, by Disease Type (CMT 1, CMT 2, CMT 3, and Others), by Drug Type (Nonsteroidal anti-inflammatory drugs, Cyclooxygenase-2 inhibitors, Tricyclic antidepressants, Anticonvulsants, Analgesics and Pipeline Drug), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies and Online Pharmacies), and by Region (North America, Europe, Asia Pacific, Middle East, Africa, and Latin America), was valued at US$ 793.9 Million in 2021 and is projected to exhibit a CAGR of 23.4% during the forecast period (2021-2028).
The key market players are focusing on the introduction of novel therapies for the treatment of charcot-marie-tooth disease, which is projected to provide a profitable opportunity for industry participants to introduce their novel products. For instance, Pharnext, an advanced clinical-stage biopharmaceutical company, provided data on its novel product PXT3003. PXT3003 is a new type of synergistic fixed-dose combination of baclofen, naltrexone, and sorbitol, administered as an oral solution twice a day. The three individual components of PXT3003 were selected to down-regulate the overexpression of PMP22 protein, thereby improving neuronal signals in dysfunctional peripheral nerves, which is a component of the pathophysiology of the disease. PXT3003 has shown promising and consistent results in phase II and phase III preclinical and clinical studies.
Global Charcot-Marie-Tooth Disease Market – Impact of Coronavirus (COVID-19) Pandemic
COVID-19 pandemic has affected various industries globally. The players operating in the global charcot-marie-tooth disease market are facing major challenges on various fronts due to the COVID-19 pandemic. According to the Coronavirus Disease (COVID-19) Weekly Epidemiological Update by the World Health Organization, the number of COVID-19 cases reported globally, as of September 24, 2021, are approximately 230,418,451 confirmed cases with 4,724,876 deaths.
The coronavirus pandemic has negatively impacted the development, production, and supply of pharmaceutical products and affected growth of the medication used in treatment of CMT disease manufactured by various companies across the regions such as North America, Europe, and Asia Pacific. Moreover, the supply and production of pharmaceutical products is also affected due to lockdown imposed globally during the COVID-19 pandemic. This lockdown has resulted in closure of industrial establishments, except manufacturing of essential commodities, and disruption in supply chain of the pharmaceutical products.