Nasal administration is a route of administration in which the drugs are insufflated through the nose for either local or systemic effect. Nasal delivery is used to treat of local infection in the nasal course and paranasal sinuses such as rhinitis and sinusitis (allergic & non-allergic). Nasal drug delivery is used to reduce the problem of slow absorption of drug, poor bioavailability, and degradation before reaching the target site. This route of administration is a convenient and reliable route of administration.
Market Statistics:
The global nasal drug delivery mode market is estimated to account for US$ 50,947.4 Mn in terms of value by the end of 2021.
Market Drivers:
Outbreak of COVID-19 (global pandemic) is expected to drive growth of the global nasal drug delivery mode market over the forecast period. COVID-19 is a respiratory disease caused by a novel coronavirus (or SARS-CoV-2). For instance, in August 2021, Glenmark Pharmaceuticals and SaNOtize Research & Development Corporation joined forces to manufacture, market, and distribute its breakthrough Nitric Oxide Nasal Spray (NONS) for COVID-19 treatment in India and other Asian markets including Malaysia, Singapore, Hong Kong, and other countries.
Market Opportunities:
Increase in development of OTC drugs (nasal drops & nasal sprays) by market players provides lucrative opportunities for the global nasal drug delivery mode market growth. For instance, in March 2019, Janssen Pharmaceutical announced that the U.S. Food and Drug Administration (FDA) has approved SPRAVATO (esketamine) CIII nasal spray for use in conjunction with an oral antidepressant in adults with treatment-resistant depression (TRD).
Market Restraints:
Regulatory hurdles and complications associated with the overuse of nasal sprays are expected to impede growth of the global nasal drug delivery mode market.
Global Nasal Drug Delivery Mode Market - Impact of Coronavirus (Covid-19) Pandemic
Intranasal drug delivery represents an important area of research for COVID-19 and other viral diseases. In 2020, Codagenix and Serum Institute of India (SII) received regulatory approval from the UK Medicines and Healthcare products Regulatory Agency (MHRA) to initiate Phase I clinical trial of COVI-VAC, a single-dose intranasal, live attenuated vaccine against COVID-19. While, in December 2020, Eureka Therapeutics announced successful preclinical results of InvisiMask Human Antibody Nasal Spray against SARS-CoV-2 infection (COVID-19). This in turn is expected to fuel the growth of the market.