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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

3D cell culture is an artificially created environment. 3D cell culture is a culture environment that allows biological cells to interact with their surroundings in all three dimensions. Cells grown in 3D cell culture exhibit similar properties of cells found in living organisms, in terms of cellular characteristics and behavior. This technique allows the cells to grow in their natural environment in an in vivo condition.

The global 3D cell culture market is estimated to be valued at US$ 2,604.3 million in 2020 and is expected to exhibit a CAGR of 23.4% during the forecast period (2020-2027).

Figure 1.Global 3D Cell Culture Market Share (%) in Terms of Value, By Technology 2020

3D Cell Culture  | Coherent Market Insights

Increasing product launches by key companies are expected to drive the market growth during the forecast period.

The increasing product launches of 3D cell cultures by regulatory authorities and key players, respectively are expected to drive the market growth over the forecast period. For instance, in January 2021, Jellagen Limited, a biotechnology company manufacturing high value Collagen Type 0 derived from jellyfish, announced the launch of JellaGel Hydrogel. 3-dimensaional hydrogels allow cells to grow and interact with all of its surroundings. Cells grown in a 3D model have proven to be more natural, with improved cell viability, morphology, proliferation, and differentiation.

Figure 2.Global 3D Cell Culture Market Share (%), by Application, 2020

3D Cell Culture  | Coherent Market Insights

Increasing R&D activities in 3D cell culture is expected to drive the market growth during the forecast period.

The increasing R&D activities in 3D cell culture is expected to aid in growth of the global 3D cell culture market, over the forecast period. For instance, in August 2020, researchers at Okayama University created a new 3D cell culture model of pancreatic cancer that closely mimics the 'fibrotic' tissue characteristically observed in patients.

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3D Cell Culture Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2020: US$ 2,604.3 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 23.4% 2027 Value Projection: US$ 11,335.1 Mn
Geographies covered:
  • North America: U.S., and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Technology: Extracellular Matrices or Scaffolds, Bioreactors, Gels, Scaffold-free Platforms, Microchips
  • By Application: Research, Drug Discovery, Tissue Engineering, Clinical Applications, Stem Cell Biology
  • By End User: Research Labs & Institutes, Biopharmaceutical Industry, Hospitals And Diagnostic Centers, Others
Companies covered:

Becton, Dickinson and Company, Thermo Fisher Scientific Inc., Lonza, Merck KGaA, 3D Biotek LLC, 3D Biomatrix, Inc., 3D Biomatrix, Inc., and REPROCELL Inc.

Growth Drivers:
  • Increasing products approvals and launches
  • Increasing R&D activities in 3D cell culture
  • Rising prevalence of cancer and infectious diseases
Restraints & Challenges:
  • Lack of consistency in products such as  Extracellular Matrices or Scaffolds

Global 3D Cell Culture Market – Impact of Coronavirus (COVID-19) Pandemic

The coronavirus (COVID-19) pandemic and lockdown in various countries across the globe has impacted the financial status of businesses in all sectors. The private healthcare is one of the sector, which has been majorly impacted by the pandemic. The lockdowns in various countries has created an economic burden on the private healthcare sector. Healthcare providers are facing challenges with regards to manpower, equipment, consumables, and other resources to ensure safety of patients with other diseases, and declining outpatient’s visits, among others. Moreover, the pandemic has negatively impacted the development, production, and supply of drugs, and affected growth of the healthcare segment of various companies across the globe. This has led to closure of industrial establishments, except manufacturing of essential commodities, and disruption in supply chain of products. The COVID-19 pandemic has affected the economy in three main ways; 1) by directly affecting the production and demand; 2) by creating disruptions in distribution channels; and 3) through its financial impact on companies and financial markets. Supply chain and manufacturing activities in India, China, U.S., and others have been disrupted due to global lockdowns. Whereas, countries such as Thailand, Indonesia, Singapore, and others are facing problems with transportation of drugs and medications. Thus, the pandemic is expected to slightly disrupt the R&D activities of the 3D cell culture market. However, currently the spread of coronavirus has spurred growth of 3D cell culture market, owing to increasing 3D cell culture for regeneration of 3D cell culture organs for understanding the mechanism of coronavirus infection.

Global 3D Cell Culture Market: Restraint

The major factors that hinder growth of the global 3D cell culture market include lack of consistency in 3D cell culture products. The lack of consistency between wells and batches of cell culture are the other major barriers in the adoption of 3D cell culture techniques. Researchers face several problems while inserting scaffold/ECM into microplate wells. This inconsistency in the products reduces the reproducibility of results and, thus, reduces the efficiency of the research.

Key Players

Major players operating in the global 3D cell culture market  include Becton, Dickinson and Company, Thermo Fisher Scientific Inc., Lonza, Merck KGaA, 3D Biotek LLC, 3D Biomatrix, Inc., 3D Biomatrix, Inc., and REPROCELL Inc.

A 3D cell culture is an in-vitro technique wherein the cells can grow in an artificially created environment. These environments closely resemble to the architecture and functioning of the native tissue. 3D cell culture technique helps stimulate cell differentiation, proliferation, and migration by interacting with their three-dimensional surroundings, as they would in the in-vivo environment. As 3D cell cultures can mimic the structure, activity, and microenvironment of the in-vivo tissues, this technique has varied applications in the fields of drug screening, regenerative medicine, stem cell therapies, and cancer research and cell biology.

Market Dynamics

Key players operating in the global 3D cell culture market are focusing on adoption of inorganic growth strategies such as acquisitions, and collaborations, which are expected to drive the market growth during the forecast period. For instance, in August 2019, CELLINK AB entered an agreement with the owners of Cytena GmbH to acquire all Cytena shares for a purchase price of US$ 36.4 million. The acquisition is in line with CELLINK’s commercial strategy, strengthening CELLINK’s product offering and providing a more complete 3D cell culturing solution. Furthermore, in June 2018, Greiner Bio-One North America, Inc. acquired 3D Cell Culture Technology assets previously owned by Nano 3D Biosciences, Inc. This strategic acquisition aims for the potential growth in the 3D cell culture market with laboratories and research facilities utilizing this new technology daily to find cures for disease and improve the existing cell culture methodology. Furthermore, in December 2019, Allevi and Lonza announced a strategic collaboration to bring the elements needed for 3D bioprinting together. Combining Lonza’s primary cells and media with Allevi’s 3D bioprinters and bioink production capabilities will empower researchers with the tools needed for plug-and-play bioprinting.

Key features of the study:

  • This report provides in-depth analysis of the global 3D cell culture market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2020–2027), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global 3D cell culture market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
  • Key companies covered as a part of this study include Becton, Dickinson and Company, Thermo Fisher Scientific Inc., Lonza, Merck KGaA, 3D Biotek LLC, 3D Biomatrix, Inc., 3D Biomatrix, Inc., and REPROCELL Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global 3D cell culture market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global 3D cell culture market

Detailed Segmentation:

  • Global 3D Cell Culture Market, By Technology:
    • Extracellular Matrices or Scaffolds
    • Bioreactors
    • Gels
    • Scaffold-free Platforms
    • Microchips
  • Global 3D Cell Culture Market, By Application
    • Research
    • Drug Discovery
    • Tissue Engineering
    • Clinical Applications
    • Stem Cell Biology
  • Global 3D Cell Culture Market, By End User:
    • Research Labs & Institutes
    • Biopharmaceutical Industry
    • Hospitals And Diagnostic Centers
    • Others
  • Global 3D Cell Culture Market, By Region:
    • North America
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Technology:
        • Extracellular Matrices or Scaffolds
        • Bioreactors
        • Gels
        • Scaffold-free Platforms
        • Microchips
      • By Application
        • Research
        • Drug Discovery
        • Tissue Engineering
        • Clinical Applications
        • Stem Cell Biology
      • By End User:
        • Research Labs & Institutes
        • Biopharmaceutical Industry
        • Hospitals And Diagnostic Centers
        • Others
      • By Country/Region
        • North Africa
        • Central Africa
        • South Africa
  • Company Profiles
    • Becton, Dickinson and Company*
      • Company Highlights
      • Products Portfolio
      • Key Highlights
      • Financial Performance
      • Strategy
    • Thermo Fisher Scientific Inc.
    • Lonza
    • Merck KGaA
    • 3D Biotek LLC
    • 3D Biomatrix, Inc.
    • InSphero AG
    • REPROCELL Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snapshot, By Technology
      • Market Snapshot, By Application
      • Market Snapshot, By End User
      • Market Snapshot, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Drivers
    • Restraints
    • Opportunity
    • Impact Analysis
    • Market Trends
    • USFDA Regulatory Scenario
    • Recent Product Launches
    • Pest Analysis
    • Technological Advancements
    • Mergers & Acquisitions
    • Key Highlights
  4. Global 3D Cell Culture Market – Impact of Coronavirus (COVID-19) Pandemic
    • Covid-19 Epidemiology
    • Impact of Covid-19 on Clinical Trials
    • Overall Impact On Countries
    • Key Developments
  5. Global 3D Cell Culture Market, By Technology, 2016 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Extracellular Matrices or Scaffolds
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Bioreactors
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Gels
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Scaffold-free Platforms
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Microchips
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  6. Global 3D Cell Culture Market, By Application, 2016 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Research
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Drug Discovery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Tissue Engineering
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Clinical Applications
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Stem Cell Biology
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  7. Global 3D Cell Culture Market, By End User, 2016 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Research Labs & Institutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
    • Biopharmaceutical Industry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
    • Hospitals And Diagnostic Centers
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  8. Global 3D Cell Culture Market, By Region, 2016 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017–2027
      • Regional Trends
    • North America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2016 – 2027, (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2016 – 2027, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2016 – 2027, (US$ Mn)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2016 – 2027, (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2016 – 2027, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Technology, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2016–2027, (US$ Million)
      • Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2016 – 2027, (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  9. Competitive Landscape
    • Becton, Dickinson and Company
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Thermo Fisher Scientific Inc.
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Lonza
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Merck KGaA
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • 3D Biotek LLC
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • 3D Biomatrix, Inc.
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • InSphero AG
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • REPROCELL Inc.
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
  10. Section
    • Research Methodology
    • About Us
    • Contact

*Browse 34 market data tables and 36 figures on "Global 3D Cell Culture Market” - Global forecast to 2027

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Frequently Asked Questions

The Global 3D Cell Culture market size was valued at US$ 2,093.7 million in 2019 and is estimated to exhibit a CAGR of 29.1% between 2020 and 2027.
Extracellular Matrices or Scaffolds segment held the major market share in 2019 owing to technological advancement in product design and increasing product approvals is expected to propel growth of the market
Major factor driving the growth of Global 3D Cell Culture market during the forecast period increasing prevalence of chronic diseases, increasing research & development , and adoption of expansion strategies from major companies.
Major factors hampering the growth of the Global 3D Cell Culture market during the forecast period constitutes of lack of reimbursement.
North America market is expected to generate the highest revenue during the forecast period.
Some of the key players operating in the market are Becton, Dickinson and Company, Corning Incorporated, Lonza Group, Thermo Fisher Scientific, Inc., 3D Biotek LLC, 3D Biomatrix, Inc., Global Cell Solutions, Inc., InSphero AG, Sigma-Aldrich Corporation (a subsidiary of Merck KGaA), and Reinnervate Ltd. (a subsidiary of ReproCELL)
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