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Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

Benzocaine is also known as americaine or anaesthesin and belongs to the class of organic compounds known as benzoic acid esters. Benzocaine is an active pharmaceutical ingredient having various medicinal properties. It is used as sexual disorders such as premature ejaculation, used as topical anesthetic in various diseases such as mouth and esophageal ulcers, used as pain relief drug in dental diseases such as tooth decay and dental caries, and used in relieving skin irritation such as vaginal irritation in females. Benzocaine API is manufactured in solid physical form, it is slightly soluble in water, and its chemical name is Ethyl 4-aminobenzoate.

The global benzocaine market size is estimated to be valued at US$ 128.9 million in 2020 and is expected to exhibit a CAGR of 2.70% over the forecast period (2020-2027).

Figure 1. Global Benzocaine Market Value (US$ Mn), 2016 - 2027

Benzocaine  | Coherent Market Insights

Increasing prevalence of dental conditions such as dental caries, periodontal diseases, and oro-dental trauma in adults globally is a major factor driving growth of the global benzocaine market. According to World Health Organization report published in 2017, globally around 2.3 billion people suffer from dental diseases such as dental caries and pro-dental trauma causing pain and discomfort in mouth. Moreover, according to the same source, approximately 530 million children were suffering from dental diseases such as tooth decay and gum diseases globally in 2017.

Furthermore, increasing prevalence of oral ulcers, also known as recurrent aphthous ulcers, globally is another factor that is expected to drive growth of the global benzocaine market. According to US National Library of Medicine Report Published in 2018, each year, approximately 5-60% of individuals are suffering from recurrent aphthous ulcers, out of which 50% of individuals suffer from mouth irritation and pain due to ulcers.

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Benzocaine Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2020: US$ 128.9 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 2.70 % 2027 Value Projection: US$ 155.3 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC, Israel, and Rest of the Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Purity: 95%, 98%, Others.
  • By Indication: Skin Irritation, Wounds, Ulcers, Hemorrhoids, Others.
Companies covered:

TCI Chemicals (India) Pvt. Ltd, Merck KGaA, ACETO Corporation, Alfa Aesar, Penta International Corporation, abcr GmbH, Indofine Chemical Co Inc, Jinzhou Jiutai Pharmaceutical Co., Ltd, Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd, Fengchen Group Co., Ltd, and Mahendra Chemicals.

Growth Drivers:
  • Robust product pipeline and approval of new benzocaine drugs
  • Rising clinical research on analgesic and antipruritic properties of benzocaine
  • Increasing incidence of diseases such as dental diseases and skin disorders
Restraints & Challenges:
  • Benzocaine has less effective time of action only for 10-20 minutes after topical application

Global Benzocaine Market – Impact of Coronavirus (Covid-19)

Following the outbreak of COVID-19 in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization has declared it a public health emergency. According to the World Health Organization’s report, the manifestation of the coronavirus (COVID-19) has resulted in more than 37 million infected individuals worldwide as of October 14, 2020.

Covid-19 has affected each and every market across the world and has also impacted the global benzocaine market in the following ways: by directly affecting the production and demand; by creating disruptions in distribution channels; and by its financial impact on firms and financial markets. Supply chain and manufacturing activities in India, China, and the U.S. have been disrupted due to nationwide lockdowns. While countries such as Saudi Arabia, UAE, Egypt, and others are facing problems with regards to transportation of drugs from one place to another.

Moreover, various guidelines are regulated by the regulating bodies during manufacturing of active pharmaceutical ingredients to avoid the spread of COVID-19 and also to reduce the contamination of active pharmaceutical ingredients during the manufacturing process. The guidelines are as follows:

According to the U.S. Food Drug and Administration Report June 2020, during the COVID-19 public health emergency, drug manufacturers should follow the following current good manufacturing practice (CGMP) regulations and recommendations regarding restriction of sick employees from production areas. Any employee or worker in production unit should be medically evaluated to check whether the individual is suffering from any infectious diseases such as COVID-19. If any of the individuals are suffering from COVID-19 symptoms, they shall be restricted from entering the production house premises in the company to avoid the contamination of drugs and active pharmaceutical ingredients (API).

Figure 2. Global Benzocaine Market Share (%), by Region, 2020

Benzocaine  | Coherent Market Insights

Among regions, North America is expected to witness significant growth in the benzocaine market during the forecast period, owing to key companies focusing on benzocaine API product launches and product approvals for treatment of various diseases such as vaginal irritation due to urinary tract infections. For instance, in 2019, Church and Dwight, Co. launched RepHresh Cooling Relief spray with active ingredient benzocaine for the treatment and relief from vaginal irritation caused in females due to urinary tract infections. RepHresh Cooling Relief Vaginal Anti-Itch Spray will be supplied as 15mL tubes providing up to 60 uses throughout in the U.S.

Key Players

Major players operating in the global benzocaine market include TCI Chemicals (India) Pvt. Ltd, Merck KGaA, ACETO Corporation, Alfa Aesar, Penta International Corporation, abcr GmbH, Indofine Chemical Co Inc, Jinzhou Jiutai Pharmaceutical Co., Ltd, Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd, Fengchen Group Co., Ltd, and Mahendra Chemicals.

Benzocaine is a benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. Benzocaine is a local anesthetic and is used to suppress the gag reflux, used as lubricant and topical anesthetic on mouth, nasal cavity, respiratory tract, oesophagus, rectum, and irritation in urinary tract in females. Benzocaine plays an important role as a topical anesthetic and is also used in conditions such as insect stings and bites, and skin irritation.

Market Dynamics

Research institutes and academic research institutes are focusing on research and development of benzocaine drugs due to its topical anesthetic properties, which is expected to drive growth of the global benzocaine market. For instance, in March 2020, Alexandria University completed the phase 2 trial of using local anesthetic gel patches such as benzocaine gel patch during the palatal injection administration. The study was conducted to reduce the pain while administering the palatal injection in patients during dentistry procedures.

Key features of the study:

  • This report provides in-depth analysis of the global benzocaine market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2020–2027), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new drug launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global benzocaine market based on the following parameters – company overview, financial performance, drugs portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include TCI Chemicals (India) Pvt. Ltd, Merck KGaA, ACETO Corporation, Alfa Aesar, Penta International Corporation, abcr GmbH, Indofine Chemical Co Inc, Jinzhou Jiutai Pharmaceutical Co., Ltd, Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd, Fengchen Group Co., Ltd, and Mahendra Chemicals
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future drug launches, market expansion, and marketing tactics
  • The global benzocaine market report caters to various stakeholders in this industry including investors, suppliers, device manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global benzocaine market

Detailed Segmentation:

  • Global Benzocaine Market, By Purity :
    • 95%
    • 98%
    • Others
  • Global Benzocaine Market, By Indication :
    • Skin Irritation
    • Wounds
    • Ulcers
    • Hemorrhoids
    • Others  
  • Global Benzocaine Market, By Region:
    • North America
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Purity:
        • 95%
        • 98%
        • Others
      • By Indication :
        • Skin Irritation
        • Wounds
        • Ulcers
        • Hemorrhoids
        • Others
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • TCI Chemicals (India) Pvt. Ltd.*
      • Company Overview
      • Material Portfolio
      • Financial Performance
      • Key Highlights
      • Market Strategies
    • Merck KGaA
    • ACETO Corporation
    • Alfa Aesar
    • Penta International Corporation
    • abcr GmbH
    • Indofine Chemical Co Inc
    • Jinzhou Jiutai Pharmaceutical Co., Ltd
    • Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd
    • Fengchen Group Co., Ltd.
    • Mahendra Chemicals

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Purity
      • Market Snippet, By Indication
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Impact Analysis
    • Market Opportunities
    • Regulatory Scenario
    • Recent Product Approval/ Launch
    • Key Development
    • PEST Analysis
    • Epidemiology
    • Mergers and Acquisitions
    • Value Chain Analysis
  4. Global Benzocaine Market, Impact of COVID-19 Pandemic
    • Post COVID-19 Impact
    • Demand and Supply Chain Analysis
    • Government Initiative
  5. Global Benzocaine Market, By Purity, 2016-2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • 95%
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • 98%
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Others
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  6. Global Benzocaine Market, By Indication, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • Skin Irritation
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Wounds
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Ulcers
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Hemorrhoids
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Others
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  7. Global Benzocaine Market, By Region, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Region, 2017–2027
    • North America
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • Germany
        • U.K.
        • France       
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, By Purity , 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2016–2027 (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  8. Competitive Landscape
    • Company Profiles
      • TCI Chemicals (India) Pvt. Ltd.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Merck KGaA
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • ACETO Corporation
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Alfa Aesar
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Penta International Corporation
        •  Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • abcr GmbH
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Indofine Chemical Co Inc
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Jinzhou Jiutai Pharmaceutical Co., Ltd
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Fengchen Group Co., Ltd.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Mahendra Chemicals
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
        • Market Strategies

 *Browse 33 market data tables and 32 figures on "Global Benzocaine Market–Global  forecast to 2027”.

Frequently Asked Questions

The global benzocaine market size is estimated to be valued at US$ 128.9 million in 2020 and is expected to exhibit a CAGR of 2.70 % between 2020 and 2027.
Increasing prevalence of various diseases such as dental disorders, hemorrhoids, anal fissures, and mouth ulcers, and increasing product launches by key companies are major factors driving the market growth.
Ulcers segment is estimated to hold major market share in the global benzocaine market, owing to increasing prevalence of oral ulcers in adults and children.
North America is estimated to generate largest revenue share in 2020 in the global benzocaine market during the forecast period.
Benzocaine constituent pharmaceutical products may lead to serious side effects such as swelling of skin and bluish color of nails, lips, and skin in individuals with skin sensitivity, which is a key factor hampering growth of the market.
Major players operating in the global benzocaine market include TCI Chemicals (India) Pvt. Ltd, Merck KGaA, ACETO Corporation, Alfa Aesar, Penta International Corporation, abcr GmbH, Indofine Chemical Co Inc, Jinzhou Jiutai Pharmaceutical Co., Ltd, Changzhou Sunlight Pharmaceutical Raw Material Co., Ltd, Fengchen Group Co., Ltd, and Mahendra Chemicals.
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