Immune Repertoire Sequencing Market, By Product Type (Assay Kits (T-Cell Receptor Kits, and B-Cell Receptor Kits) and Instruments), By Application (Cancer Immunotherapy, Biomarker Discovery, Autoimmune Diseases, Vaccine Development and Efficacy, Transplant Rejection and Tolerance, Infectious Diseases, and Other Applications), By End User (Diagnostic Labs, Biotechnology and Pharmaceutical Companies, Academic and Research Institutes, and Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2018-2026

  • Published On : Feb 2019 |
  • Pages : 200 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Immune Repertoire Sequencing Market – Insights

Immune repertoire sequencing is extensively used in biomarker discovery to improve the success rate and cost-effectiveness of rational drug development. For instance, in November, 2017, the Center for Commercialization of Cancer Immunotherapy (C3i) started offering T cell receptor-beta sequencing services in its Biomarker and Diagnostic unit in Canada. Increasing demand for personalized medicine, in turn, is expected to aid the immune repertoire sequencing market growth, as personalized medicine uses an individual’s genetic profile to guide decisions made in regard to the diagnosis, prevention, and treatment of diseases.

The global immune repertoire sequencing market size was valued at US$ 114.3 million in 2017, and is expected to witness a CAGR of 5.6% over the forecast period (2018 – 2026).

Global Immune Repertoire Sequencing Market Share (%) Analysis, By Product Type, 2017

Source: Coherent Market Insights Analysis (2018)

Increasing Research & Development and Demand for Genomic and Repertoire Sequencing-based Research is expected to Drive Growth of the Immune Repertoire Sequencing Market

Increasing research and development and launches of novel products by key players are expected to be the major driving force for global immune repertoire sequencing market growth in the near future. For instance, in 2016, ArcherDX, Inc. expanded its product portfolio with the launch of Archer Immunoverse immune repertoire sequencing assays at the American Society of Hematology (ASH). In 2017, ArcherDX, Inc. launched Archer Immunoverse B Cell Receptor (BCR) assays to characterize the human B cell repertoire.

According to a study published by Cold Spring Harbor Laboratory, in 2017, researchers from Stanford University applied immune repertoire sequencing to identify disease-related signatures in the immune systems of patients with systemic sclerosis-related pulmonary hypertension (SSc-PAH), a rare chronic autoimmune disease that affects the connective tissue. Therefore, increasing research on immune repertoire sequencing is expected to create a favorable environment for immune repertoire sequencing market growth in the near future.

Immune Repertoire Sequencing Market - Restraints

Challenges in immune repertoire sequencing include distinguishing biological variations from the errors and the bias introduced in different steps. Conventional and novel bioinformatics techniques such as high throughput screening, Haystack Heuristic, and others are not up to the mark due to unsatisfactory scalability and sensitivity, and limitation in providing sufficient and accurate data. Moreover, the differences of data generation and processing in different laboratories along with the challenges in immune repertoire sequencing system are some key factors, which may hamper growth of the immune repertoire sequencing market size.

Immune Repertoire Sequencing Market - Regional Insights

On the basis of region, the global immune repertoire sequencing market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold a dominant position in the global immune repertoire sequencing market during the forecast period, owing to high presence of key industry players in the region (including Illumina Inc., Thermo Fisher Scientific, Pacific Biosciences, and CD Genomics). These players are increasingly focusing on development of novel technologies for immune repertoire sequencing. For instance, in 2017, 10x Genomics Inc., U.S. based company, added B-Cell and 5’Unbiased Enrichment Kit to its chromium immune repertoire profiling solution or immune repertoire sequencing.

Europe is expected to foresee a rapid growth in the immune repertoire sequencing market. The market in Europe is expected to gain momentum during the forecast period, owing to rise in funding by the government bodies to support international innovative projects and marketable innovative products, processes, and services, in order to cater unmet medical need. In July 2018, Eurostars (a joint program between EUREKA and the European Commission) granted US$ 495,000 to OSE Immunotherapeutic SA’s project entitled: ‘Treatment Response Monitoring for Cancer Immunotherapies Using Immune Repertoire Analysis’.

Global Immune Repertoire Sequencing Market Value (US$ Mn) & Y-o-Y Growth (%), 2016-2026

   

 Source: Coherent Market Insights Analysis (2018)

Immune Repertoire Sequencing Market - Competitive Landscape

Key players operating in the global immune repertoire sequencing market include Thermo Fisher Scientific, Inc., Illumina Inc., ArcherDX, Inc., Roche Holding AG, Pacific Biosciences, CD Genomics, Atreca, Inc., Adaptive Biotechnologies, Oxford Nanopore Technologies, Ltd., Qiagen N.V., Agilent Technologies, Inc., and Takara Bio, Inc.

Immune repertoire refers to sub-type protein that an organism’s immune system creates. Immune systems in vertebrates have six key types of proteins- two immunoglobulin and four T cell receptors. Immune repertoire sequencing enables researchers and scientists to examine and understand adaptive immune-mediated diseases. Immune repertoire sequencing is also widely applicable in biomarker discovery, infectious disease research, asthma and allergy research, and cancer immunotherapy.

Market Dynamics

Increasing prevalence of cancer worldwide is expected to boost immune repertoire sequencing market growth. According to National Cancer Institute, 2016, an estimated 16.8 million new cases of cancer were diagnosed in the U.S., with around 595,690 deaths from the disease. Moreover, the number of people suffering from cancer is expected to reach to 19 million by 2024. According to the Cancer Atlas, 2012, about 1.1 million new cancer cases and 600,000 cancer deaths are reported annually in Latin America and the Caribbean, where lung cancer is the leading cause of cancer death for both sexes.

However, factors such as high cost associated with certain sequencing platforms and data analytic services coupled with product recalls are expected to hinder growth of the immune repertoire sequencing market during the forecast period. For instance, in 2015, Illumina Inc. recalled its Illumina MiSeqDx Universal Kit 1.0, due to software limitation when using the product on MiSeqDx instrument. The software could not report insertions or deletions at specific genomic locations with respect to the primer.

Key features of the study:

  • This report provides in-depth analysis of the immune repertoire sequencing market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2018 – 2026, considering 2017 as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles key players in the global immune repertoire sequencing market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Thermo Fisher Scientific, Inc., Illumina Inc., ArcherDX, Inc., Roche Holding AG, Pacific Biosciences, CD Genomics, Atreca, Inc., Adaptive Biotechnologies, Oxford Nanopore Technologies, Ltd., Qiagen N.V., Agilent Technologies, Inc., and Takara Bio, Inc.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The global immune repertoire sequencing market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors, and suppliers for immune repertoire sequencing market, research and consulting firms, new entrants, and financial analysts

 

Detailed Segmentation:

  • Global Immune Repertoire Sequencing Market, By Product Type:
    • Assay Kits
      • T-Cell Receptor (TCR) Kits
      • B-Cell Receptor (BCR) Kits
    • Instruments
  • Global Immune Repertoire Sequencing Market, By Application:
    • Cancer Immunotherapy
    • Biomarker Discovery
    • Autoimmune Diseases
    • Vaccine Development and Efficacy
    • Transplant Rejection and Tolerance
    • Infectious Diseases
    • Other Applications
  • Global Immune Repertoire Sequencing Market, By End User:
    • Diagnostic Labs
    • Biotechnology and Pharmaceutical Companies
    • Academic and Research Institutes
    • Others
  • Global Immune Repertoire Sequencing Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Product Type:
        • Assay Kits
          • T-Cell Receptor (TCR) Kits
          • B-Cell Receptor (BCR) Kits
        • Instruments    
      • By Application:
        • Cancer Immunotherapy
        • Biomarker Discovery
        • Autoimmune Diseases
        • Vaccine Development and Efficacy
        • Transplant Rejection and Tolerance
        • Infectious Diseases
        • Other Applications
      • By End User:
        • Diagnostic Labs
        • Biotechnology and Pharmaceutical Companies
        • Academic and Research Institutes
  • Company Profiles
    • Thermo Fisher Scientific, Inc.*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Illumina Inc.
    • ArcherDX, Inc
    • Roche Holding AG
    • Pacific Biosciences
    • CD Genomics
    • Atreca, Inc.
    • Adaptive Biotechnologies
    • Oxford Nanopore Technologies, Ltd.
    • Qiagen N.V.
    • Agilent Technologies, Inc.
    • Takara Bio, Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Regulatory Landscape
    • Product Recall
    • Epidemiology Analysis
    • Technology Overview
    • PEST Analysis
    • Porter’s Five Forces model
  4. Global Immune Repertoire Sequencing Market, By Product Type, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Assay Kits
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
        • T-Cell Receptor (TCR) Kits
        • B-Cell Receptor (BCR) Kits
    • Instruments
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  5. Global Immune Repertoire Sequencing Market, By Application, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Cancer Immunotherapy
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Biomarker Discovery
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Autoimmune Diseases
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Vaccine Development and Efficacy
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Transplant Rejection and Tolerance
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Infectious Diseases
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Other Applications
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  6. Global Immune Repertoire Sequencing Market, By End User, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Diagnostic Labs
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Biotechnology and Pharmaceutical Companies
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Academic and Research Institutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  7. Global Immune Repertoire Sequencing Market, By Region, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2017 – 2026
      • Regional Trends
    • North America
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Company Profiles
      • Thermo Fisher Scientific, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Illumina Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • ArcherDX, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Roche Holding AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Pacific Biosciences
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • CD Genomics
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Atreca, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Adaptive Biotechnologies
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Oxford Nanopore Technologies, Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Qiagen N.V.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Agilent Technologies, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Takara Bio, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 38 market data tables and 27 figures on "Immune Repertoire Sequencing Market” - Global forecast to 2026”

Research Methodology

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In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Data Standardization:

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Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

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