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Knee Replacement Market Analysis & Forecast: 2025-2032

Knee Replacement Market, By Procedure (Total Knee Replacement, Partial Knee Replacement, Kneecap Replacement, Revision Knee Replacement), By Implant Type (Fixed-bearing Implants, Mobile-bearing Implants, Medial Pivot Implants, Others), By Material (Metal-on-Plastic, Ceramic-on-Plastic, Ceramic-on-Ceramic, Metal-on-Metal), By End User (Hospital, Orthopedic Clinics, Ambulatory Surgery Centers, Others), By Geography (North America, Latin America, Europe, Asia Pacific, Middle East & Africa)

  • Published In : 14 Jul, 2025
  • Code : CMI4328
  • Pages :194
  • Formats :
      Excel and PDF
  • Industry : Medical Devices
  • Historical Range: 2020 - 2024
  • Forecast Period: 2025 - 2032

Knee Replacement Market Size and Trends Forecast – 2025 to 2032

The knee replacement market is estimated to be valued at USD 12.37 Bn in 2025 and is expected to reach USD 17.18 Bn by 2032, exhibiting a compound annual growth rate (CAGR) of 4.8% from 2025 to 2032.

Key Takeaways of the Knee Replacement Market

  • By procedure, the total knee replacement segment is expected to account for 60. 6% of the market share in 2025.
  • By implant type, the mobile-bearing implants segment is estimated to contribute the highest market share of 50. 12% in 2025.
  • By material, the ceramic-on-ceramic segment is estimated to contribute the highest market share of 49. 13% in 2025.
  • North America remains the dominant player in the knee replacement market and is estimated to account for 40. 7% of the global market share in 2025.

Market Overview

Knee Replacement Market Key Factors

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Global knee replacement market is expected to witness significant growth over the forecast period, due to rising geriatric population worldwide and increasing number of osteoarthritis and rheumatoid arthritis cases. Increasing sport injuries and road accidents that damage the knee ligaments can boost the demand for knee replacement surgeries. Furthermore, rapid innovation in technologies and development of advanced implants and instrumentation for replacement surgeries are making them safer and more effective.

However, high cost of knee replacement surgeries and prolonged recovery time post-surgery can hamper the market growth.

Market Concentration and Competitive Landscape

Knee Replacement Market Concentration By Players

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Current Events and their Impact on the Knee Replacement Market

Current Events

Description and its impact

Regulatory Policy Shifts

  • Description: Regulatory reforms in key markets are reshaping the knee replacement landscape. The EU Medical Device Regulation (MDR) aims to streamline certification for innovative implants, encouraging faster market entry while initially raising compliance costs. In the U.S., the CMS Bundled Payment (CJR) Model extends financial responsibility to hospitals for 90-day postoperative care, incentivizing better outcomes and efficiency. Additionally, the introduction of mandatory Patient-Reported Outcome Measures (PROMs) by 2025 requires providers to systematically track patient recovery and satisfaction after surgery.
  • Impact: These shifts are pushing the knee replacement market toward greater accountability and value-based care, favoring manufacturers with cost-effective, outcome-driven solutions. While larger players can absorb rising regulatory and reporting costs, smaller providers may struggle, leading to potential market consolidation.

Geopolitical and Economic Pressures

  • Description: Global trade tensions and economic headwinds are creating significant challenges for the knee replacement market. The U.S.-China tariff escalation has imposed up to 145% duties on Chinese components, impacting manufacturing costs and delaying product timelines. In addition, EU retaliatory trade measures threaten U.S. device exports, prompting American firms to consider shifting production to lower-cost regions like India. Adding to the strain, widespread medtech R&D budget cuts—with nearly 37% of firms freezing hiring—are slowing innovation, particularly in next-gen and minimally invasive knee technologies.
  • Impact: These pressures are forcing companies to rethink global supply chains, regionalize manufacturing, and delay non-essential product development. Rising costs and regulatory complexity may drive implant price inflation of 15–20%, ultimately burdening healthcare providers and patients. Innovation in cutting-edge knee replacement systems could stall, widening the gap between large multinationals and smaller players struggling to adapt to this volatile economic and geopolitical landscape.

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Market Trends

Increasing Incidence of Road Accidents Leading to Amputations

Increasing number of road accidents across the globe can drive the global knee replacement market growth. Knee injuries are one of the most common injuries suffered in road accidents involving vehicles. Severe knee injuries often lead to long term impairment and disability, which can only be treated by knee replacement surgeries.

Rising Prevalence of Osteoarthritis

Rising prevalence of osteoarthritis, the most common cause of knee replacements, can drive the market growth. Osteoarthritis occurs when the protective cartilage that cushions the ends of bones wears down over time. This causes friction and irritation in the joint. The knee is one of the weight-bearing joints that bears the brunt of osteoarthritis due to factors like increased life expectancy, obesity, and physical inactivity among older populations.

For instance, according to the World Health Organization (July 2023), osteoarthritis affects approximately 365 million people globally in the knee. This makes it the most frequently impacted joint followed by the hip and hand. Additionally, 344 million individuals with osteoarthritis experience moderate to severe symptoms that could benefit from rehabilitation interventions.

Segmental Insights

Knee Replacement Market By Procedure

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Knee Replacement Market Insights, By Procedure: Demand for Joint Replacement Surgeries Boosts Total Knee Replacement Segment Growth

In terms of procedure, total knee replacement segment is estimated to contribute the highest market share of 60.6% in 2025, owing to the increasing demand for joint replacement surgeries among aging populations globally.

Total knee replacement procedures help alleviate chronic joint pain and restore mobility in patients suffering from severe osteoarthritis or other degenerative conditions of the knee joint. As life expectancy rises worldwide, there has been an increase in the number of elderly individuals experiencing joint disorders. This rising geriatric demographic boosts demand.

Knee Replacement Market Insights, By Implant Type: Material Innovations Boosts Adoption of Mobile-Bearing Implants

In terms of implant type, mobile-bearing implants segment is estimated to contribute the highest market share of 50.12% in 2025. Mobile implants allow more natural knee movement by maintaining flexibility in the insert that acts as a cushion between the femoral component and tibial component.

The key advantage of mobile-bearing implants over fixed implants is lower risk of implant loosening over time as these experience less shear stress at the bone-implant interfaces. Furthermore, material advancements have made these implants more durable and comfortable for patients. Manufacturers continue innovating new polymer and alloy formulations that mimic natural joint properties more closely.

Knee Replacement Market Insights, By Material: Ceramic Components Boosts Demand for Ceramic-on-Ceramic Materials

In terms of material, the ceramic-on-ceramic segment is estimated to contribute the highest market share of 49.13% in 2025, due to biocompatibility and wear resistance advantages of ceramic components.

Ceramic bearings have very low friction coefficients minimizing wear particulate release which often leads to osteolysis in other material combinations over the long term. Since ceramic is very stable and durable, ceramic-on-ceramic implants undergo negligible wear even after 10-15 years post-surgery. Absence of corrosion or allergic reactions with ceramic further elevates its biocompatibility.

Emerging Innovations in the Knee Replacement Market

  1. Robotic-assisted surgery

Application: Using real-time imaging and computer guidance, surgeons now can plan and perform total knee replacement surgery with greater precision, tailored to your exact knee anatomy. This helps ensure better alignment and implant positioning, potentially improving longer-lasting results.

Example: In June 2024, Jhansi Orthopaedic Hospital announced the launch of revolutionary medical technology. This meticulous mapping allows for optimal placement of the knee implant, significantly reducing the potential for human error.

  1. Smart knee implants

Application: These high-tech implants are equipped with tiny sensors that track the performance of the new knee joint. Healthcare providers can monitor recovery remotely, adjust rehabilitation plans as necessary, and detect potential issues early. This results in fewer in-person follow-up visits and more personalized recovery care.

Example: The Persona IQ Smart Knee implant represents a significant advancement in orthopedic innovation. It integrates the personalized fit of the Persona Knee system with a smart stem extension equipped with sensors that continuously collect motion data following knee replacement surgery.

Impact of Artificial intelligence (AI) on the Knee Replacement Market

Knee replacement management in clinical trials is being revolutionized by AI-powered solutions

  • AI powers robotic systems used in knee replacement procedures, enhancing surgical precision, reducing human error, and improving postoperative outcomes.
  • AI algorithms aid in the development of next-generation implants by analyzing large datasets to optimize material use, joint mechanics, and longevity.
  • AI-enabled smart knee implants and wearable devices monitor patient movement, detect anomalies, and provide feedback to healthcare providers for personalized care.

Regional Insights

Knee Replacement Market Regional Insights

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North America Knee Replacement Market Analysis and Trends

North America is the dominant region in the global knee replacement market with an estimated market share of 40.7% in 2025. The large size of the market in the U.S., along with strong healthcare infrastructure and high healthcare spending has made North America the premier location for major knee replacement device manufacturers. Several leading global players like Zimmer Biomet, Stryker Corporation and Johnson & Johnson have sizable operations and manufacturing facilities located in the U.S., catering to the local as well as international demand.           

For instance, in March 2025, at AAOS in San Diego, Zimmer Biomet showcased a comprehensive portfolio of orthopedic and musculoskeletal innovations. The company highlighted its Z1 Triple‑Taper hip system, introduced newly launched knee and upper-extremity reconstructive technologies including the FDA-cleared Persona Revision SoluTion Femur and unveiled its ZBX Ambulatory Surgery Center solutions to support expanded outpatient capabilities.

Asia Pacific Knee Replacement Market Analysis and Trends

The Asia Pacific region has emerged as the fastest growing market for knee replacements globally in the recent years. In particular, countries like China, Japan and India have witnessed double digit growth, and are gradually catching up to developed markets. This can be attributed to growing awareness about treatment options and rising affordability of implants and surgeries.

For instance, in February 2025, Singapore's Alexandra Hospital developed world's first A.I. algorithm for robotic knee replacements. As the world's first computational algorithm for robotic total knee replacement (rTKR), the new AI algorithm is granted an international Patent Cooperation Treaty (PCT) patent.

U.S Knee Replacement Market Analysis and Trends

The presence of major orthopedic surgical centers and growing geriatric population suffering from osteoarthritis has boosted the number of knee replacement surgeries in the U.S. The pricing of knee implants is also regulated by government bodies, thus, ensuring affordability for patients.

For instance, in November 2024, Zimmer Biomet received Food and Drug Administration approval for Oxford Cementless Partial Knee, Only Cementless Partial Knee Replacement Implant in the U.S.

India Knee Replacement Market Analysis and Trends

India's market is still untapped and holds huge future potential. Growing medical tourism where patients travel to India from other Asian and African countries for affordable surgeries has further boosted the knee replacement volumes in the country.

For instance, according to data released by the credit rating agency Crisil, the number of medical tourists visiting India is projected to reach approximately 7.3 million in 2024, up from an estimated 6.1 million in 2023. World-class amenities, a pool of skilled and well-trained medical experts and cost-effective treatment alternatives make India an appealing destination for those seeking high-quality healthcare services. India has become a popular choice for ‘medical value travel’ in recent times.

Germany Knee Replacement Market Analysis and Trends

Germany serves as the largest market for knee replacements in Europe, fueled by a strong orthopedic infrastructure and a well-established public healthcare system. A significant portion of the elderly population requires joint replacements, while national initiatives to reduce surgical waiting times have accelerated procedural volumes. Additionally, Germany’s emphasis on digital health integration is boosting the adoption of AI-powered navigation systems and smart implants, enhancing procedural outcomes and postoperative care.

Brazil Knee Replacement Market Analysis and Trends

In Brazil, expanding private healthcare infrastructure, rising geriatric demographics, and increasing awareness about orthopedic care propel market growth. Urban populations are increasingly seeking joint replacement procedures, while public-private collaborations are improving access to advanced implants. The country is also seeing growing interest in minimally invasive techniques and robotic-assisted knee replacements, particularly in private hospitals in São Paulo and Rio de Janeiro.

Pricing Analysis

  • Small to Mid-Sized Healthcare Providers
    • Pricing for knee replacement implants typically ranges from USD 2,500 to USD 7,000 per procedure, depending on implant type, brand, and surgical complexity.
    • Basic implant packages with standard materials and limited customization are priced at the lower end, suitable for smaller hospitals and clinics.
  • Large Hospitals and Specialty Orthopedic Centers
    • Costs can range between USD 7,000 to USD 15,000+ per procedure, often including premium implants with advanced coatings, customized sizing, and robotic-assisted surgery fees.
    • High-end providers charge additional fees for cutting-edge technology like patient-specific instrumentation (PSI) and computer navigation systems.

Market Report Scope

Knee Replacement Market Report Coverage

Report Coverage Details
Base Year: 2024 Market Size in 2025: USD 12.37 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 4.8% 2032 Value Projection: USD 17.18 Bn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Procedure: Total Knee Replacement, Partial Knee Replacement, Kneecap Replacement, and Revision Knee Replacement
  • By Implant Type: Fixed-bearing Implants, Mobile-bearing Implants, Medial Pivot Implants, and Others
  • By Material: Metal-on-Plastic, Ceramic-on-Plastic, Ceramic-on-Ceramic, and Metal-on-Metal
  • By End User: Hospital, Orthopedic Clinics, Ambulatory Surgery Centers, and Others
Companies covered:

Zimmer Biomet Holdings, Inc., Stryker Corporation, DePuy Synthes (a Johnson & Johnson company), Smith & Nephew plc, B. Braun Melsungen AG, Medtronic plc, Conformis Inc., MicroPort Scientific Corporation, DJO Global, Inc., Exactech Inc., Corin Group, Waldemar LINK GmbH & Co. KG, Arthrex Inc., Kinamed Incorporated, Bioimpianti, Ortho Development Corporation, THINK Surgical, Inc., and OMNIlife science Inc.

Growth Drivers:
  • Increasing incidence of road accidents Leading to Amputations
  • Rising Prevalence of Osteoarthritis
Restraints & Challenges:
  • High cost of knee replacement surgery
  • Risk of post-surgery complications

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Global Knee Replacement Industry News

  • In March 2025, Stryker a global leader in medical technologies, showcased the latest advancements in Mako SmartRobotics across hip, knee, spine and shoulder procedures at the American Academy of Orthopaedic Surgeons’ (AAOS) 2025 Annual Meeting in San Diego. With over 1.5 million Mako procedures performed globally across 45 countries, Mako is a market-leading technology in orthopedics.
  • In June 2025, Johnson & Johnson launched KINCISE 2 System, the only automated surgical impactor approved for knee and hip revision procedures.
  • In March 2025, Smith+Nephew, the global medical technology company, featured the latest advancements in Orthopaedic Reconstruction at the American Academy of Orthopaedic Surgeons Annual Meeting in San Diego.
  • In February 2025, Exactech, a global leader in medical technology, presented 15 new studies describing new research and advancements in total joint arthroplasty and trauma solutions at the 2025 Orthopaedic Research Society (ORS) Annual Meeting in Phoenix, Ariz.

Analyst View

  • Global knee replacement market is expected to witness growth, due to rising geriatric population worldwide who are more prone to knee injuries and conditions like osteoarthritis. However, high cost of knee replacement surgeries and prolonged recovery time post-surgery can hamper the market growth.
  • North America currently dominates the market, owing to the well-established healthcare infrastructure and technology in the region. However, Asia Pacific is likely to be fastest growing market, due to improving healthcare facilities and rising medical tourism in countries like India, China, and Southeast Asian nations.
  • Within procedure segment, total knee replacement dominates as it provides a permanent solution to chronic knee problems. Non-compartmental or partial knee replacement procedure is growing at a higher rate due to the benefits of fewer complications and faster recovery time.
  • There has been huge demand for revision knee replacement surgeries as a greater number of young active adults opt for knee replacements. This offers opportunities for market players to develop innovative solutions catering to need for revision knee joints with high durability.

Market Segmentation

  •  Procedure Insights (Revenue, USD Bn, 2020 - 2032)
    • Total Knee Replacement
    • Partial Knee Replacement
    • Kneecap Replacement
    • Revision Knee Replacement
  •  Implant Type Insights (Revenue, USD Bn, 2020 - 2032)
    • Fixed-bearing Implants
    • Mobile-bearing Implants
    • Medial Pivot Implants
    • Others
  •  Material Insights (Revenue, USD Bn, 2020 - 2032)
    • Metal-on-Plastic
    • Ceramic-on-Plastic
    • Ceramic-on-Ceramic
    • Metal-on-Metal
  •  End User Insights (Revenue, USD Bn, 2020 - 2032)
    • Hospital
    • Orthopedic Clinics
    • Ambulatory Surgery Centers
    • Others
  • Regional Insights (Revenue, USD Bn, 2020 - 2032)
    • North America
      • U.S.
      • Canada
    • Latin America
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
    • Europe
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Middle East
      • GCC Countries
      • Israel
      • Rest of Middle East
    • Africa
      • South Africa
      • North Africa
      • Central Africa
  • Key Players Insights
    • Zimmer Biomet Holdings, Inc.
    • Stryker Corporation
    • DePuy Synthes (a Johnson & Johnson company)
    • Smith & Nephew plc
    • B. Braun Melsungen AG
    • Medtronic plc
    • Conformis Inc.
    • MicroPort Scientific Corporation
    • DJO Global, Inc.
    • Exactech Inc.
    • Corin Group
    • Waldemar LINK GmbH & Co. KG
    • Arthrex Inc.
    • Kinamed Incorporated
    • Bioimpianti
    • Ortho Development Corporation
    • THINK Surgical, Inc.
    • OMNIlife science Inc.

Primary Research Interviews

  • Orthopedic Surgeons Specialized in Knee Replacement
  • Hospital Procurement Managers
  • Medical Device Distributors
  • Physical Therapist

Magazines

  • Orthopaedic design and Technology Magazine
  • Knee Surgery and Related Research Magazine
  • Others

Journals

  • The Journal of Arthroplasty
  • Journal of Knee Surgery

Associations

  • American Academy of Orthopedic Surgeons (AAOS)
  • International Society of Technology in Arthroplasty (ISTA)
  • European Knee Associates (EKA)
  • Orthopedic Research Society (ORS)

Public Domain Sources

  • U.S. Food and Drug Administration (FDA), Medical Device Database
  • World Health Organization (WHO) Global Health Observatory
  • Centers for Disease Control and Prevention (CDC) Orthopedic Reports
  • National Center for Biotechnology Information (NCBI)

Proprietary Elements

  • CMI Data Analytics Tool – Knee replacement Market
  • CMI Existing Repository of Information for the Last 8 Years

*Definition: The knee replacement market refers to the global industry focused on the development, manufacturing, and distribution of knee implants, surgical instruments, and related technologies used in knee arthroplasty procedures. These procedures involve the partial or total replacement of damaged or diseased knee joints with artificial components to relieve pain and restore mobility, primarily in patients with osteoarthritis, rheumatoid arthritis, or knee injuries. The market encompasses total knee replacement (TKR), partial knee replacement (PKR), revision surgeries, and increasingly, robot-assisted and AI-integrated systems that enhance surgical precision and patient outcomes.

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About Author

Manisha Vibhute is a consultant with over 5 years of experience in market research and consulting. With a strong understanding of market dynamics, Manisha assists clients in developing effective market access strategies. She helps medical device companies navigate pricing, reimbursement, and regulatory pathways to ensure successful product launches.

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Frequently Asked Questions

The knee replacement market is estimated to be valued at USD 12.37 Bn in 2025, and is expected to reach USD 17.18 Bn by 2032.

The CAGR of the knee replacement market is projected to be 4.8% from 2025 to 2032.

Increasing incidence of road accidents leading to amputations and the rising prevalence of osteoarthritis are the major factors driving the growth of the global knee replacement market.

High cost of knee replacement surgery and risk of post-surgery complications are the major factors hampering the growth of the global knee replacement market.

In terms of procedure, the total knee replacement subsegment is estimated to dominate the market in 2025.

Zimmer Biomet Holdings, Inc., Stryker Corporation, DePuy Synthes (a Johnson & Johnson company), Smith & Nephew plc, B. Braun Melsungen AG, Medtronic plc, Conformis Inc., MicroPort Scientific Corporation, DJO Global, Inc., Exactech Inc., Corin Group, Waldemar LINK GmbH & Co. KG, Arthrex Inc., Kinamed Incorporated, Bioimpianti, Ortho Development Corporation, THINK Surgical, Inc., and OMNIlife science Inc. are the major players in the global knee replacement market.

North America is expected to lead the global knee replacement market in 2025.

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