Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), provide the enhanced resolution, along with the powerful chemometric software, that allows the simultaneous determination and comparison of thousands of chemical entities, which has lead to an expansion of small molecule biochemistry studies in bacteria, plants, and mammals. Targeted and untargeted metabolomics service are the two major types of metabolomics services.
The global metabolomics services market is estimated to be valued at US$ 483.74 million in 2022 and is expected to exhibit a CAGR of 14.2% during the forecast period (2022-2030).
Figure 1. Global Metabolomics Services Market Share (%), by Service Type, 2022
Global Metabolomics Services Market - Drivers
Adoption of inorganic growth strategies such as product launches by key market players is expected to drive the global metabolomics services market over the forecast period. For instance, in June 2021, Thermo Fisher Scientific Inc., a manufacturer of analytical instruments, announced that they had launched Orbitrap IQ-X Tribrid mass spectrometer which enables confident structure elucidation and unknown analytes identification. The wide range applications of Orbitrap IQ-X Tribrid mass spectrometer include metabolomics and lipidomics research, leachable impurities identification, and forensic toxicology.
|Base Year:||2021||Market Size in 2022:||US$ 483.74 Mn|
|Historical Data for:||2017 to 2020||Forecast Period:||2022 to 2030|
|Forecast Period 2022 to 2030 CAGR:||14.2%||2030 Value Projection:||US$ 1,396.79 Mn|
Thermo Fisher Scientific Inc., Agilent Technologies, Inc., SCIEX (Danaher), Waters Corporation, Shimadzu Corporation, Bruker, Human Metabolome Technologies Inc., LECO Corporation, Biocrates life sciences AG, Metabolon, Inc., Metabolomic Technologies Inc., PerkinElmer Inc., Analytik Jena GmbH, Creative Proteomics, Vproteomics, DNA Xperts Private Limited, MS-OMICS, metaSysX, BASF SE, BGI, Afekta Technologies Ltd., Metware Biotechnology Co.,Ltd.
|Restraints & Challenges:||
Figure 2. Global Metabolomics Services Market Share (%), by Region, 2022
Global Metabolomics Services Market – Impact of Coronavirus (COVID-19) Pandemic
Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.
COVID-19 can affect the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, the U.A.E., Egypt, and others are facing problems with the transportation of drugs from one place to another.
However, the COVID-19 pandemic had a negative impact on the global metabolomics services market. For instance, in March 2021, according to the data published in article Nature, by using the application targeted and untargeted metabolomics with gas chromatography-mass spectrometry (GC-MS) and ultra-high-pressure liquid chromatography-mass spectrometry (UHPLC-MS) on plasma samples of patients were diagnosed with SARS-CoV-2 infection and compared to 27 ambulatory patients with flu-like symptoms, negative for COVID-19. Thus, 77 metabolites exhibited stage-dependent alterations in their plasma concentration. From these metabolites, 57 were increased in critical care patients and among 30 metabolites, 29 were higher and 1 lower in critical than in mild cases.
Global Metabolomics Services Market: Key Developments
Increasing adoption of inorganic growth strategies such as product launches by key market players is expected to drive the global metabolomics services market growth over the forecast period. For instance, in June 2022, Shimadzu Corporation, a medical equipment company, announced that they had launched LCMS-2050 high-performance liquid chromatograph mass spectrometer, which is used to discover the presence or absence of impurities in the pharmaceutical and chemical fields, and for the confirmation of synthetic products and measurement of the amounts of ingredients in food products.
Global Metabolomics Services Market: Restraint
Various challenges associated with the metabolomics is expected to hinder the global metabolomics market over the forecast period. For instance, according to an article published in national library of medicine, in January 2019, challenges typically arise during the sample collection, processing, and laboratory analysis phases. The type of specimen, collection method, storage conditions, and profiling-related variables such as analytical batch can impact metabolomic profiles and add noise to the data.
Global Metabolomics Services Market - Key Players
Major players operating in the global metabolomics services market include Thermo Fisher Scientific Inc., Agilent Technologies, Inc., SCIEX (Danaher), Waters Corporation, Shimadzu Corporation, Bruker, Human Metabolome Technologies Inc., LECO Corporation, Biocrates life sciences AG, Metabolon, Inc., Metabolomic Technologies Inc., PerkinElmer Inc., Analytik Jena GmbH, Creative Proteomics, Vproteomics, DNA Xperts Private Limited, MS-OMICS, metaSysX, BASF SE, BGI, Afekta Technologies Ltd., Metware Biotechnology Co.,Ltd.
Metabolomics is defined as the large scale study of all small molecules, commonly known as metabolites, within cells, biofluids, tissues or organisms. It is the study of substrates and products of metabolism. Metabolomics is an evolving field to comprehensively identify and quantify all endogenous and exogenous low-molecular-weight (<1 kDa) small metabolites in a biological system in a high-throughput manner which are influenced by both genetic and environmental factors, lifestyle factors, medication, and underlying disease. Collectively, these small molecules and their interactions within a biological system are known as the metabolome. The metabolome is downstream of the transcriptome and proteome and is considered to be complementary to genomics, transcriptomics, and proteomics. Metabolomics services include targeted and untargeted metabolomics services. Metabolomics has various applications in health and disease including drug assessment, biomarker discovery, nutrigenomics, clinical toxicology, crop breeding, etc. Mass spectrometry based metabolomics provides a useful approach for both identification of disease related metabolites in biofluids or tissue and also encompasses classification and characterization of disease or treatment-associated molecular patterns generated from metabolites.
Increasing adoption of inorganic strategies such as research collaboration, in order to provide metabolomics services by key market players is expected to drive the global metabolomics services market over the forecast period. For instance, in July 2021, Thermo Fisher Scientific Inc., a manufacturer of analytical instruments, announced that they had entered into a research collaboration with the University of California, Davis, to launch Center of Excellence in clinical metabolomics to develop new technologies and reproducible analytical techniques to support rapid, cost-effective clinical research into applications for metabolomics in precision medicine.
Key features of the study:
“*” marked represents similar segmentation in other categories in the respective section.