Western blotting, also called as immunoblotting, is a subtype of blotting technique that is used to separate and identify proteins. Various steps in western blotting include, tissue preparation, gel electrophoresis, transfer of proteins onto membrane, blocking to prevent membrane and antibody interactions, incubation of membrane, and antibody-based detection of proteins.
The global western blotting market accounted for US$ 605.7 Mn in terms of value and is expected to reach US$ 993.4 Mn by the end of 2027.
Global Western Blotting Market: Drivers
Increasing prevalence of HIV/AIDS is expected to boost growth of the global western blotting market over the forecast period. For instance, according to Joint United Nations Program on HIV/AIDS, 37.9 million people globally were living with HIV at the end of 2018.
Moreover, increasing applications of western blotting technique is also expected to propel growth of the market. For instance, in January 2020, researchers at British Antarctic Survey, Natural Environment Research Council, U.K., reported used of western blotting in assessment of post-translationally deiminated protein and EV profiles of plasma in seabird species from the Antarctic.
North America region held dominant position in the global western blotting market in 2018, accounting for 34.4% share in terms of value, followed by Europe.
Global Western Blotting Market: Restraints
Emergence of alternative technologies is expected to hamper growth of the market. For instance, AlphaScreen technology is an emerging and highly sensitive homogenous bead-based platform, which is used in the detection of biomolecules. The technique does not involve the cumbersome wash-steps and detects any molecule of interest, largely from protein complexes.
Moreover, western blot technique is a semi-quantitative process and can give only an approximate measurement. This drawback is also expected to hinder growth of the market.
Global Western Blotting Market: Opportunities
Introduction of better imaging software for management of western blotting results is expected to offer lucrative growth opportunities for players in the global western blotting market. Increasing use of western blotting results in generation of large amount of data, which needs to be stored, organized, and interpreted. Use of photo management software for scanning film-based results and creating albums will enable space saving, random access, result backup, and easy result sharing.
Key players in the market can focus on developing digital western blotting in order to enhance their market share. However, the use of conventional western blotting systems is high due to high costs of automated systems.
Product type segment in the global western blotting market was valued at US$ 605.7 Mn in 2018 and is expected to reach US$ 993.4 Mn by 2027 at a CAGR of 5.4% during the forecast period.
Market Trends/Key Takeaways
The use of western blotting in R&D in cancer has significantly increased. For instance, in January 2020, researchers at The First Affiliated Hospital of Soochow University, China, reportedly used western blotting in the investigating the role of microRNA-708 (miR-708) in cervical cancer.
The market is also witnessing increasing use of fluorescent western blotting in protein detection as it produces less chemical waste and is a reliable method of collecting quantitative data. It can also be used to detect multiple proteins simultaneously.
Global Western Blotting Market: Competitive Landscape
Major players operating in the global western blotting market include, Thermo Fisher Scientific, Inc., GE Healthcare, Hoffmann-La Roche Ltd., Danaher Corporation (Lumigen, Inc.), EMD Millipore Corporation, Bio-Rad Laboratories, Inc., PerkinElmer Inc., LI-COR, Inc., Bio-Techne Corporation (ProteinSimple Inc.), and Advansta, Inc.
Global Western Blotting Market: Key Developments
Key players in the market are focused on adopting M&A strategies to expand their product portfolio. For instance, in June 2019, Bio-Techne Corporation reached agreement to acquire B-MoGen Biotechnologies Inc.
Major players in the market are also focused on product launch to expand their product portfolio. For instance, in November 2019, Bio-Rad Laboratories, Inc. launched EveryBlot Blocking Buffer, a western blot blocking reagent that offers 5-minute blocking time and produces higher signal and lower background levels.
Western blotting is a technique used for detection of protein. It is also called as immunoblotting technique wherein specific antibodies are used to detect antigens. It works on the principle of molecular weight of the proteins and specificity. Gel electrophoresis is used for the denaturation of proteins and to obtain the primary antibody. Blotting and testing is performed later where the primary antibody binds to its specific antigen. It gives a qualitative and semi – quantitative type of analysis, i.e., it can evaluate size and amount of protein. Western blotting technique has several applications in diagnostics and confirmatory tests and is also used for qualitative analysis of proteins and cells and in blood doping tests. Blotting technique is used as an analyzing tool in cell and molecular biology. Western blotting technique, also called as immunoblotting technique, is a subtype of blotting technique. Western blotting is generally used to separate and identify proteins.
Restraints of the Global Western Blotting Market
Western blot technique is a semi-quantitative process and can give only an approximate measurement. Moreover, presence of alternative techniques such as ELISA (enzyme-linked immunosorbent assay), which is much faster and simpler process compared to western blotting technique, is expected to hamper the global western blotting market growth.
Key features of the study:
“*” marked represents similar segmentation in other categories in the respective section.