Bone Marrow Transplant Market – Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026

  • To Be Published : Sep 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Bone marrow transplant is a medical procedure to replace bone marrow damaged or destroyed by disease, infection, or chemotherapy. Bone marrow transplant procedure involves transplanting blood stem cells that travel to the bone marrow where they produce new blood cells and promote growth of new marrow. Bone marrow is the spongy, fatty tissue inside human bones, which creates the different parts of blood such as red blood cells that carry oxygen and nutrients throughout the body; white blood cells that fight infection; and platelets responsible for formation of clots. Bone marrow also contains juvenile blood forming stem cells known as hematopoietic stem cells (HSCs). The HSC found in the bone marrow constantly creates new blood cells. Bone marrow transplant replaces damaged stem cells with healthy cells. This helps the body produce optimum levels of white blood cells, platelets, or red blood cells to avoid infections, bleeding disorders, or anemia. For transplantation, healthy stem cells are procured from a compatible donor, or healthy bone marrow is extracted from a non-affected part in the patient’s body.

According to Centre for Disease Control (CDC), around 14.1 million people worldwide were diagnosed with cancer in 2012, leading to 8.2 million fatalities. Furthermore, around 19.3 million new cases of cancer are projected to be diagnosed by 2025. Also, prevalence of sickle cell anemia is increasing worldwide. This inadvertently would augment demand for bone marrow transplant, thereby fueling growth of the overall bone marrow transplant market.

Bone Marrow Transplant Market

On the basis of transplantation type, the global market is classified into:

    • Allogeneic Bone marrow Transplantation
    • Autologous Bone Marrow Transplantation

On the basis of the disease indication, the global market is classified into:

    • Lymphoma
    • Leukemia
    • Myeloma
    • Myelodysplasia
    • Aplastic Anemia
    • Sickle cell Anemia
    • Solid tumors
    • Thalassemia
    • Myeloproliferative Neoplasms

On the basis of the end user, the global market is classified into:

    • Multispecialty Clinics
    • Hospitals
    • Ambulatory Surgical Centers

According to Centre for Disease control and prevention (CDC), cancer is one of the most prevalent chronic diseases, with around 20.3 million cases diagnosed in 2014. The U.S government is taking initiatives to prevent and cure the disease as a result of which, large investments in this field are expected in the near future. For instance, the National Institutes of Health (NIH), an institute of the U.S. Department of Health and Human Services (HHS), is the primary federal agency for conducting and supporting medical research. It is composed of 27 Institutes and Centers, including the National Cancer Institute (NCI), and which provides leadership and financial support to researchers in the U.S. and throughout the world.

Increasing prevalence of cancers and anemia all over the world is the major driver for the growth of global bone marrow   transplant market. And also, advances in technology, improving healthcare infrastructure, emerging indications of bone marrow transplant for heart and neuronal disorders, growing investment in logistic services, increasing per capita healthcare expenditure are some other factors expected to flourish the global bone marrow transplantation market. Major challenges for global bone marrow transplant market are high cost involved in the treatment and acute dearth of bone marrow donors.

Europe would retain its dominance in the global bone marrow transplant market in the foreseeable future. This is mainly attributed to high density of bone marrow transplant centers and growing bone marrow registries in the region. Latin America is estimated to witness rapid increase in volume of bone marrow transplant industry, due to high number of potential candidates for the procedure. Asia Pacific is characterized by relatively low prevalence of bone marrow related diseases and thus would not witness rampant growth in the near future. However, owing to easy access to high quality healthcare services at relatively low costs, the region is expected to emerge as a hub for medical tourists seeking bone marrow transplant.

Key players operating in the global bone marrow transplant market include STEMCELL Technologies, Merck Millipore Corporation, Sanofi-Aventis LLC., AllCells LLC., ReachBio LLC., Conversant Bio, Cruline Human biospecime PRO, PromoCell GmbH, and Lifeline Cell Technology.

Key Developments

  1. Major companies in the market are focused on various growth strategies such as gaining product approval from regulatory authorities, in order to gain competitive edge in the market. For instance, in October 2017, AstraZeneca plc, a U.K.-based pharmaceutical company, and Acerta Pharma, its haematology research and development center of excellence, received the U.S. Food and Drug Administration (FDA) approval to Calquence (acalabrutinib), which is indicated for adult patients with mantle cell lymphoma.
  2. Key players in the market are involved in various business strategies such as gaining product approval from regulatory authorities, in order to expand their product portfolio. For instance, in July 2019, Karypharma Therapeutics Inc., an oncology-focused pharmaceutical company, received, the U.S. FDA approval for XPOVIO (selinexor), which is indicated for the treatment of patients with relapsed or refractory multiple myeloma.
  3. Key companies in the global market are focused on various growth strategies such as gaining product approval from regulatory authorities, in order to enhance their market presence. For instance, in January 2019, Novartis International AG, a Swiss pharmaceutical company, received the U.S. FDA approval for its crizanlizumab (SEG101) breakthrough therapy, which is indicated for prevention of vaso-occlusive crises (VOCs) in patients with sickle cell disease (SCD).

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