Acellular Dermal Matrices Market Analysis

Acellular dermal matrix is a biologically derived product, which is devoid of cells. The main components of acellular dermal matrix include collagen and elastic fibers. It has applications in plastic surgery, general surgery, breast reconstruction, cosmetic surgery, wound healing, and others. The matrix is derived from different sources such as human, porcine, bovine, and others.

Global Acellular Dermal Matrices Market - Impact of the Coronavirus (COVID-19) Pandemic

COVID-19 pandemic is expected to decrease the growth of the global acellular dermal matrices market over the forecast period. For instance, according to the World Heart Federation, 2020, older people over the age of 60 years and people suffering from underlying medical conditions such as cardiovascular disease, hypertension, diabetes, chronic respiratory disease, and cancer are more prone to the coronavirus infection compared to younger population. Furthermore, according to World Health Organization (WHO), on April 2, 2020, it was reported that in Europe, 95% of the coronavirus infection was recorded in the population older than 60 years, while over 50% of the infection were recorded in the population of the age group of 80 years and more.

According to the Breast Cancer Now, research and care organization: 18^th September 2020, around 1,500 breast cancer patients, breast reconstructive surgery got delayed due to COVID-19 pandemic. According to the same source, in the U.K., around 55,000 women and 370 men are diagnosed with breast cancer per year. Moreover, in UK, 14,850 of the 55,000 women undergo breast mastectomy each year. Such delay in the breast reconstruction surgeries may affect the self-esteem, body image and sexuality in patients, which is expected to hamper the market growth over the forecast period.

The global acellular dermal matrices market is estimated to be valued at US$ 6,483.6 Mn in 2020 and is expected to exhibit a CAGR of 15.1% over the forecast period (2020-2027).

Figure 1: Global Acellular Dermal Matrices Market Share (%) Analysis, By Material Type, 2020

Increasing product launches by the market players is expected to drive growth of the global acellular dermal matrices market over the forecast period.

Market players are involved in launching new products in different regions, which is expected to increase the customer base, thereby driving growth of the global acellular dermal matrices market over the forecast period. For instance, in 2019, LifeNet Health, Inc., launched first human acellular dermal matrices, Dermacell AWM. The matrix is indicated for wound treatment such as diabetes foot ulcer.

Acellular Dermal Matrices Market Report Coverage

Report Coverage	Details
Base Year:	2019	Market Size in 2020:	US$ 6,483.6 Mn
Historical Data for:	2017 to 2019	Forecast Period:	2020 to 2027
Forecast Period 2020 to 2027 CAGR:	15.1%	2027 Value Projection:	US$ 17,360.7 Mn
Geographies covered:	North America: U.S. and Canada Latin America: Brazil, Argentina, Mexico, and Rest of Latin America Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific Middle East: GCC, Israel, and Rest of Middle East Africa: South Africa, North Africa, and Central Africa
Segments covered:	By Material Type: Polyhydroxyalkanoate (PHA), Silicone, Dispersants, Others. By Tissue Origin: Human, Porcine, Bovine, Others. By Application: Orthopedics, Plastic Surgery, General Surgery, Repair and Replacement of Tissue (Wound Coverage), Dental, Others.
Companies covered:	Zimmer Biomet, Stryker Corporation, Staumann, Allergan, Inc., Conmed, Integra LifeSciences Corporation, Aziyo Biologics, Hospital Innovations, Medtronic, Inc., Synthes, Inc., Gunze Corp., Cook Medical Incorporated, C. R. Bard, Inc., and HANS BIOMED CORP.
Growth Drivers:	Increasing product launches Increasing acquisitions Increasing number of breast reconstruction surgeries Increasing awareness about the breast reconstruction program among the population
Restraints & Challenges:	Increasing side-effects due to plastic surgery procedure Increasing product recalls

Increasing inorganic activities such as acquisitions is expected to fuel growth of the global acellular dermal matrices market.

Market players are involved in organic activities such as acquisitions, which is expected to drive acellular dermal matrices market growth over the forecast period. For instance, in 2017, Allergan Inc., acquired LifeCell Corporation, a regenerative medicine company. Allergan Inc., is focused on offering acellular dermal matrices products for the plastic surgeons, by combining the innovative medical aesthetics and plastic surgery portfolio of Allergan Inc., and LifeCell Corporation.

Rising number of plastic surgeries worldwide is expected to drive growth of the global acellular dermal matrices market over the forecast period. For instance, according to the American Society of Plastic Surgeons: 2019, globally, the total number of cosmetic procedures carried out in 2019 and 2018 were 18,160,785 and 17,902,692, respectively. Out of which the minimally invasive cosmetic procedures carried out in 2019 and 2018 were 16,349,031 and 16,090,952 respectively. The cosmetic procedures involving the acellular dermal matrix carried out in 2019 and 2018 were, 9,117 and 8,575.

Increase number of plastic surgery procedures worldwide is expected to drive the global acellular dermal matrices market growth over the forecast period.

The following table depicts the number of plastic surgeries carried out in different countries worldwide. The number of plastic surgeries carried out in the U.S., are highest, as compared to other countries in the world.

Global Acellular Dermal Matrices Market – Restraints

Increasing side-effects due to plastic surgery procedure is expected to hamper growth of the market over the forecast period. For instance, according to the NCBI, 2016, side effects such as seroma, implant loss, mastectomy skin necrosis, and others may result due to plastic surgery procedures. Moreover, according to the Plastic and Reconstructive Surgery Journals: February 2019, in the U.S., the rate of plastic surgeries are high as compared to other countries and the rate of side-effects such as skin necrosis are caused in 8-15% of the patients undergoing plastic surgery.

Moreover, increasing product recalls is expected to restrain growth of the global acellular dermal matrices market. For instance, in 2019, TEI Biosciences, Inc., a subsidiary of Integra Life sciences Corporation’s product PriMatrix, an acellular dermal tissue matrix derived from fetal bovine dermis was recalled due to quality of the matrix. Such factors contribute in restraining growth of the acellular dermal matrices market over the forecast period.

Global Acellular Dermal Matrices Market – Regional Analysis

On the basis of region, the global acellular dermal matrices market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

North America is expected to dominate the global acellular dermal matrices market, owing to the increasing awareness of breast cancer and increasing number of plastic surgeries in the region. For instance, in November 2018, breast reconstruction awareness program was conducted in the Windsor Regional Hospital, Canada, with the special purpose to help and educate local women about breast cancer and breast reconstruction. Moreover, according to the International Society of Aesthetic Plastic Surgery: in 2019, highest number of plastic surgery procedures were carried out in the U.S., i.e., 18.7%.

Furthermore, Asia Pacific is also estimated to witness significant growth in the acellular dermal matrices market, owing to increasing government initiatives about breast cancer treatment. For instance, in February 2018, the state health department of Tamil Nadu, India launched free cosmetic surgery clinic at the Government Stanley Medical College and Hospital, which offers free breast reconstruction surgery, as well as breast augmentation and breast reduction surgeries for people below the poverty line.

Figure 2: Global Acellular Dermal Matrices Market (US$ Mn), by Region, 2020

Global Acellular Dermal Matrices Market – Competitive Landscape

Major players operating in the global acellular dermal matrices market include Zimmer Biomet, Stryker Corporation, Staumann, Allergan, Inc., Conmed, Integra LifeSciences Corporation, Aziyo Biologics, Hospital Innovations, Medtronic, Inc., Synthes, Inc., Gunze Corp., Cook Medical Incorporated, C. R. Bard, Inc., and HANS BIOMED CORP.