Dendrimers and Polymer Drugs Conjugate Market, by Dendrimer Type (Poly – etherhydroxyethyl amine (PEHAM), Poly - esterhydroxyethyl amine (PEA), Poly - amido amine (PAMAM), Poly – L – lysine, Poly – propylene imine, and Others), By Application (Oncology, Infectious Diseases, and Others), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Size, Share, Outlook, and Opportunity Analysis, 2018 – 2026

  • To Be Published : Jun 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Dendrimers, and polymer drug conjugates are nano–sized medicines used for therapeutic applications. In polymer drug conjugates, polymers are covalently bonded to the drug molecule and the linkers are biologically active. Dendrimers are highly water soluble, polyvalent, and have precise molecular weight. They act as carriers of drugs, and facilitate their administration in the body. Dendrimers also have other applications in diagnostic analyses, target therapy, and vaccines. They are also used for the treatment of cancer. Other commercially available polymer drug conjugates include VivaGel, Dendrimer – docetaxel, and Dendrimer – oxaliplatin among others.

Global Dendrimers and Polymer Drugs Conjugate Market Drivers

Product launches, and collaboration activities of manufacturers are expected to boost the global dendrimers and polymer drugs conjugate market growth. For instance, in April 2019, VivaGel was officially launched in Australia by Aspen Pharmacare and commercialized by Starpharma. Vivagel is used for the treatment of bacterial vaginosis, a non-antibiotic therapy.  It contains astodrimer sodium which is a type of dendrimer. It is the only treatment which is available over the counter, i.e., without prescription. Such partnerships are expected to propel the growth of global dendrimers and polymer drugs conjugate market. Furthermore, in September 2015, AstraZeneca entered a license agreement with Starpharma Holdings Limited. AstraZeneca used their DEP technology, a type of dendrimer drug delivery system, to study several cancer compounds in the early phases of development.

Advancements in drug delivery systems with an edge over to the conventional drug delivery system is expected to propel the global dendrimers and polymer drugs conjugate market growth.  Dendrimers have more stability and prolonged circulation than the conventional (oral drug delivery system) approach of drug delivery system. Certain dendrimers are about 200 nanometer in size, and their high loading antigen capacity receives stronger responses from immune system than oral vaccines. For example, polyamidoamine (PMAM) is a dendrimer which has a spherical shape. PAMAM functionality can be altered and has highly reactive surfaces, hence it can deliver encapsulated drugs to the target cell more efficiently. This factor is expected to drive the global dendrimers and polymer drugs conjugate market growth.

Global Dendrimers and Polymer Drugs Conjugate Market Regional Analysis

North America is expected to be the dominant region in the global dendrimers and polymer drugs conjugate market. Presence of manufacturers like Eli Lilly & Co., Dade Behring and Nektar Therapeutics, potential customer base, and frequent research and development activities by key players is expected to drive North America dendrimers and polymer drugs conjugate market growth. For instance, in November 2016, Nektar Therapeutics commenced its investigational study on NKTR-102. The drug is being studied for the treatment of metastatic breast cancer. It contains irinotecan (dendrimer)/ Topoisomerase I inhibitor, and is currently in the third phase of clinical trial. Such key research and development activities are expected to drive the global dendrimers and polymer drugs conjugate market growth.

Global Dendrimers and Polymer Drugs Conjugate Market Restraints

Disadvantages associated with employment of dendrimers and polymer conjugated drugs may hamper the global dendrimers and polymer conjugate market growth. Dendrimers are used in pharmaceutical industry, however their biological use is restricted due to their toxicity. The interaction between the positive charge present on the surface area of dendrimers and the negative charge present on the biological membrane leads to membrane erosion and thinning. It disrupts the membrane and can cause cytotoxicity, hematological toxicity and hemolytic toxicity. Hence, this factor may restrain the use of dendrimers and polymers in potential pharmaceutical applications, and also hinder the global dendrimers and polymer drugs conjugate market growth.

Global Dendrimers and Polymer Drugs Conjugate Market Key Players

Some of the major players operating in the global dendrimers and polymer drugs conjugate market include, Starpharma Holdings Ltd., AstraZeneca Plc., Eli Lilly & Co., Nektar Therapeutics, Dade Behring, Stiefel Laboratories, Cerulean Pharma Inc., Merck KGaA, Qiagen and CTI Biopharma Corp.

Global Dendrimers and Polymer Drugs Conjugate Market Taxonomy

The global dendrimers and polymer drugs conjugate market is segmented on the basis of dendrimers type, applications, distribution channel, and region.

By Dendrimers Type

  • Poly – etherhydroxyethyl amine (PEHAM)
  • Poly - esterhydroxyethyl amine (PEA)
  • Poly - amido amine (PAMAM)
  • Poly – L – lysine
  • Poly – propylene imine
  • Others

By Applications

  • Oncology
  • Infectious Diseases
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By Region

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Smiley face

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
Smiley face

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Choose License Type

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

[email protected]

Key Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.