Herpes Simplex Virus (HSV) Vaccines Market, by Vaccine (GEN-003, VCL-HB01, HSV529, and Others), by Indication (HSV-1 (Oral Herpes) and HSV-2 (Genital Herpes)), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – 2019-2026

  • To Be Published : Aug 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Herpes simplex virus (HSV) is known for causing herpes infection. This is majorly found on genitals or mouth and can also be seen on various body parts. There are two types of herpes simplex virus, type 1 (HSV-1) and type 2 (HSV-2), in which HSV-1 is oral herpes causing sores around lips and mouth (fever blisters or cold sores), while HSV-2 is genital herpes, wherein sores are found around genitals and rectum. HSV-1 is very common and extremely contagious infection, and HSV-1 infections occurring around mouth are known as orolabial, oral-labial, or oral –facial herpes. A very few cases of genital herpes (infections occur in genital or anal area) are found in HSV-1. Herpes simplex virus (HSV-2) is most common sexually transmitted virus causing genital herpes (GH) and also highly contagious infection. HSV-2 infection is long lasting and incurable. There is more risk for patients suffering from HSV-2 of getting human immunodeficiency virus (HIV) infection. Probability of reoccurrence of HSV-1 is less frequent than that of HSV-2.

Global Herpes Simplex Virus (HSV) Vaccines Market Drivers

Factors such as extensive research and development is expected to support global herpes simplex virus (HSV) vaccines market growth over the forecast period. Leading players in the market such as GlaxoSmithKline (GSK), Sanofi SA, and others have HSV vaccines in the development phases. GSK’s vaccine SB208141 completed phase III studies in 2009, which started in 2003. GSK carried out several other clinical trial studies on the same vaccine, considering various different parameters and formulations (with or without monophosphoryl lipid adjuvant [MPL]). Sanofi Pasteur has vaccine HSV529 for HSV-2 is in phase I, whose clinical trial study started in 2015 and completed in 2018. Moreover, Vical, Inc. has VCL-HB01, whose phase I study started in September 2016, and completed in December 2018. Furthermore, Genocea Biosciences, Inc. vaccine GEN-003 is in phase II study where the study started in November 2015 and completed in May 2017. The company also carried out various trial studies with the same vaccine by using an adjuvant Matrix-M2 (It is human respiratory syncytial virus, derived from Quillaja saponins, cholesterol, and phosphatidylcholine). Therefore, robust pipeline is expected to propel global herpes simplex virus (HSV) vaccines market growth over the forecast period.

According to Centers for Disease Control and Prevention (CDC) in 2015 HSV-1 prevalence was 47.8% while HSV-2 was 11.9% in the U.S.  According to the same source, linear increase in prevalence for both HSV-1 and HSV-2 in people aged within 14-19 is 27%, for population aged within 20–29 is 41%, and for the age ranging within 30–39 and 40–49 it is 54.1% and 59.7%, respectively. According to the World Health Organization (WHO), in 2017, around 3.7 billion people (67%) under age 50 years suffered from HSV-1 infection, and 417 million (11%) people aged 15-49 years suffered from HSV-2 infection, globally. This high rate of prevalence has created need for prevention and treatment of HSV, which is expected to support global herpes simplex virus (HSV) vaccines market growth.

Global Herpes Simplex Virus (HSV) Vaccines Market Regional Analysis

Extensive research and development activities in North America are expected to propel herpes simplex virus (HSV) vaccines market growth in the region during the forecast period. Several leading companies are focusing towards research and development of herpes simplex virus (HSV) vaccines for prevention of it. For instance, GEN-003 of Genocea Biosciences, Inc. (based in the U.S.) has shown acceptable safety profile in phase III clinical trials in 2017, so it could be first upcoming vaccine available for HSV in the market boosting global herpes simplex virus (HSV) vaccines market growth.

According to the World Health Organization (WHO) regional infection prevalence estimates for HSV-1 among people range aged 0-49 years are 49% women and 39% men in U.S., 87% women and 87% men in Africa, 69% women and 61% men in Europe, and 74% women and 73% men in western pacific are found, while for HSV-2 are found to be highest in Africa (31.5%) than compared to the U.S. (14.4%). According to the same source, in many emerging economies, herpes simplex virus type-2 (HSV-2) infection is replacing chancroid and syphilis infections as a risk factor in development of genital ulcer diseases.

Global Herpes Simplex Virus (HSV) Vaccines Market Restraints

Though several companies are carrying out clinical trials for HSV vaccines, there is absence of a prophylactic and therapeutic vaccine in the market. However, few trails have shown promising results for prevention and treatment of HSV in clinical trials. Animal studies have shown potential results in clinical trials, however, different pathophysiology of the disease in animals and humans makes it difficult to produce the same results in human trials. For instance, clinical studies in mice and guinea pigs have produced more positive results than compared to human trials, as human HSV infection is different from that of animal HSV infection. These factors have restrained global herpes simplex virus (HSV) vaccines market growth.

Global Herpes Simplex Virus (HSV) Vaccines Market Key Players

Some of the major players operating in the global herpes simplex virus (HSV) vaccines market include Sanofi S.A., GlaxoSmithKline Plc., Genocea Biosciences, Inc., Vical, Inc., and others.

Global Herpes Simplex Virus (HSV) Vaccines market Taxonomy

By Vaccine:-

  • GEN-003
  • VCL-HB01
  • HSV529
  • Others

By Indication:-

  • HSV-1 (Oral Herpes)
  • HSV-2 (Genital Herpes)

By Region  

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Smiley face

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
Smiley face

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Choose License Type

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

[email protected]

Key Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.