Renal Denervation Devices Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2017–2025

Renal denervation is a catheter-based minimally invasive procedure. It is a therapy carried out by radiofrequency or ultrasound ablation for uncontrolled hypertension. Renal denervation is performed through endovascular catheter-based procedure to treat hypertension, which is beyond medication control. The procedure consists of a catheter that emits radiofrequency energy across multiple electrodes. Radiofrequency pulse is applied to the renal artery, which causes the wall of artery to ablate, reducing the nerve activity, thereby reducing blood pressure. The progress of catheter-based interventional therapies has yielded impressive results in certifying enhanced blood pressure control in patients with complaints of uncontrolled hypertension, vascular, and cardiovascular diseases.

Effective treatment through minimally invasive catheter-based endovascular procedure to drive market growth

According to the International Journal of Hypertension in 2013, atrial hypertension affects around 24.8% of the global population, posing morbidity and mortality. Rising prevalence of hypertension with inefficient anti-hypertensive medicines, lasting effect of renal denervation, and fast development of renal denervation devices are expected to drive the growth of renal denervation devices market. The market is expected to grow drastically with the FDA approval of Symplicity HTN-4 renal denervation device, owing to its targeted radiofrequency energy delivery, thereby minimizing the potential threat to surrounding tissues. The market for renal denervation devices and associated processes is also driven by advantages such as higher safety, reduced treatment time, permanent effect, and rising incidence of  uncontrolled & treatment-resistant hypertension.

Symplicity system is the largest segment expected to fuel the market, owing to reduction in radiofrequency energy required

The global renal denervation devices market is segmented on the basis of product type, technology, end user, and geography.

On the basis of product type, the global renal denervation devices market is segmented into:

  • Symplicity Renal Denervation System
  • Vessix Renal Denervation System
  • EnligHTN
  • Paradise Renal Denervation System
  • Iberis Renal Sympathetic Denervation System

On the basis of technology, the global renal denervation devices market is segmented into:

  • Radiofrequency
  • Ultrasound
  • Cryoablation
  • Micro-infusion

On the basis of end user, the global renal denervation devices market is segmented into:

  • Hospitals
  • Ambulatory Centers
  • Others

Europe is expected to account for maximum market share, owing to the significant R&D investments by market participants operating in the region

Regional segmentation of the global renal denervation devices market by Coherent Market Insights comprises North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. The renal denervation devices market in Europe is considered to be the biggest, owing to the increasing number of drug-resistant hypertension cases and technological advances for manufacturing efficient devices. According to the American Heart Association estimates in 2013, around 33% (nearly 70 million people) of the U.S. adult population suffer from high blood pressure. The rising occurrence of uncontrolled hypertension and increasing FDA approvals for drugs are expected to be the major factors driving market growth in North America in the forecast period.

Innovation in products is expected to generate higher revenue for the manufacturers

Key players operating in the renal denervation devices market include Medtronic Plc., St. Jude Medical, ReCor Medical Inc., Boston Scientific Corporation, and Cardiosonic Ltd. The market participants are engaged in research and development for introducing innovative and differentiated products in the market. For instance, Symplicity HTN-2 developed by Medtronic and EnligHTN TN developed by St. Jude Medical are proven to be effective and therefore are largely adopted by patients. Other prominent vendors include Ablative Solutions Inc., Mercator MedSystems Inc., Jude Medical Inc., and Terumo Medical Corporation, among others.

Research Methodology

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  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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