Zika Vaccines Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026

  • To Be Published : Jul 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Zika vaccines are developed for immunization & prevention against diseases caused by Zika virus. This virus belongs to genus Flavivirus and is transmitted by Aedes mosquitoes. The virus can also be transmitted through blood transfusion, sexual contact or from infected pregnant women to the fetus. Diagnosis of this infection is confirmed by detecting viral DNA through PCR. However, only 1 in 4 people with zika infection are prone to develop symptoms. In November 2016, the World Health Organization (WHO) declared that zika infection no longer constitutes a Public Health Emergency of International Concern (PHEIC) as major cases of zika virus were asymptomatic.

In April 2015, a major ongoing outbreak of Zika virus was registered in Brazil, which later affected the population in South and Central America. This outbreak caused mild illness (fever, rashes, joint pains, conjunctivitis, nausea, and muscle pain), though the recent outbreaks showed severe complications such as microcephaly, Guillain-Barré syndrome, and various congenital neurological abnormalities in infants who were born to infected mothers. The link between zika virus and microcephaly and Guillain-Barré syndrome was identified and reported in 2015 in Brazil.

According to the Centers for Disease Control and Prevention (CDC), 70 new zika virus infection cases were reported in the U.S. in 2015, which increased to 41,181 cases in 2016. Lack of reporting is a major factor for lower incidence rate in 2015. Increase in awareness can result in more diagnosis and reporting thus generating growth of the global zika vaccines market.

Researchers at the Queensland University of Technology found that the extract of San Francisco plant (Codiaeum variegatum) found in Australia, can kill the zika virus. This extract can arrest the virus and stop it from replicating without causing any damage to the host cells.

Zika Vaccines Market Taxonomy:

There are different types of vaccines that provide protection against Zika virus:

  • DNA-based vaccines
  • Inactivated vaccines
  • Live-attenuated vaccines
  • mRNA vaccines
  • Genetically engineered vaccines

Global market by application:

  • Therapeutic Vaccines
  • Preventive Vaccines

Global market by end user:

  • Hospitals
  • Clinics

Continuous increase in human clinical trials and rise in number of zika cases will drive the growth of Zika vaccines market

As of March 2016, 67 companies and research institutions were working on various kinds of R&D projects and clinical trials aided to develop effective vaccines against zika virus. The FDA approved the first human clinical trial for GLS–5700 in June 2016, a zika vaccine being developed by Inovio Pharmaceuticals. Further in 2017, a grant was approved for phase 2 clinical trials for a DNA vaccine conducted by NIAID’s Vaccine Research Center (VRC).

Increasing awareness among the population would aid in controlling the incidence rate of zika infection. The WHO implemented a global framework for creating public awareness through its Zika Strategic Response Framework and Joint Plan in February 2016. This plan outlines all the points to be taken care of at the time of infections. In June 2016, WHO Regional Office for Europe developed a training curriculum to increase awareness by the publication of Zika Risk Assessment for European Region.

High investment costs required for R&D and the development of effective zika virus vaccines serves as a restraining factor for the global zika vaccines market.

While major of the Zika virus cases occur in tropical regions such as Brazil, Paraguay, Venezuela, Colombia and Suriname, there are higher chances of mosquito infections in tropical areas of the U.S. like Texas and Florida. According to Pan American Health Organization, around 1,246 suspected and confirmed cases were reported between epidemiological week (EW) 10 and EW 14 of 2016 in the sub region which involves Brazil, Argentina, Peru and Ecuador.

Competitive Landscape

Some key players operating in the zika vaccines market are Cerus Corporation, Biken Inc, GlaxoSmithKline plc, Bharat Biotech International Pvt. Ltd, GeneOne Life Science, Inovio Pharmaceuticals, Immunovaccine Inc., NewLink Genetics Corp. and Sanofi S.A. The companies launched various R&D measures and clinical trials to attain immunogenicity against zika virus. In February 2016, Sanofi S.A launched a vaccine research and development project, with the introduction of Dengvaxia (Dengue vaccine) that will aid the company understand the Zika virus and develop an effective vaccine against it. Likewise, Inovio Pharmaceuticals initiated a clinical study of zika vaccine (GLS-5700) in Puerto Rico in August 2016. This trial may provide a potential push to Inovio’s vaccine if positive results are reported as there was a rapid progression of zika outbreak in Puerto Rico at that time. This could benefit the trial in assessing true efficacy and safety of the vaccine. Rapid progression in clinical trials and approval would augment the zika vaccines market growth.

Research Methodology

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  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
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  • Technology indicators

Data Processing

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Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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