The Global Transthyretin Amyloidosis Treatment Market, by Drug Type (Tafamidis (Vyndaqel), Patisiran (ONPATTRO), Inotersen (TEGSEDI), and Others), by Disease Type (Hereditary Transthyretin Amyloidosis (Polyneuropathy, Cardiomyopathy, and Mixed) and Wild Type), and by Distribution Channel (Hospital Pharmacies, Specialty Pharmacies, Retail Pharmacies, and Online Pharmacies) and by Geography (North America, Latin America, Europe, Asia-Pacific, Middle East and Africa) is expected to be valued at US$ 35.8 million in 2018 and is projected to exhibit a CAGR of 55.4% over the forecast period (2018–2026), as highlighted in a new report published by Coherent Market Insights.
Launch of novel therapies indicated for the treatment of transthyretin amyloidosis is expected to propel growth of the market. For instance, in October 2018, Alnylam Pharmaceuticals, Inc. launched ONPATTRO (patisiran) in Germany. The drug is indicated for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adults with stage 1 or stage 2 polyneuropathy. In October 2018, Ionis Pharmaceuticals, Inc. and Akcea Therapeutics, Inc. received the U.S. Food and Drug Administration (FDA) approval for its novel drug TEGSEDI (inotersen) indicated for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.
Key manufacturers in market have their novel therapies under development pipeline and are expected to gain approval in the near future. Presence of robust pipeline is also expected to be one the major factors driving the market growth. For instance, in March 2018, Pfizer, Inc. reported positive results from Phase 3 ATTR-ACT study of Tafamidis among patients suffering from transthyretin cardiomyopathy
Browse 35 Market Data Tables and 43 Figures spread through 221 Pages and in-depth TOC on Global Transthyretin Amyloidosis Treatment Market, by Drug Type (Tafamidis (Vyndaqel), Patisiran (ONPATTRO), Inotersen (TEGSEDI), and Others), by Disease Type (Hereditary Transthyretin Amyloidosis (Polyneuropathy, Cardiomyopathy, and Mixed) and Wild Type), and by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) - Forecast to 2026
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Key players in the market are focused on strategic mergers and partnerships in order to enhance their market share. For instance, In October 2018, Ionis Pharmaceuticals, Inc. and Akcea Therapeutics, Inc. entered into distribution agreement with Accredo specialty pharmacy, a subsidiary of Express Scripts to distribute TEGSEDI (inotersen) subcutaneous injection for the treatment of polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. In August 2018, Alnylam Pharmaceuticals, Inc. partnered with US Bioservices, a specialty pharmacy and part of AmerisourceBergen, to dispense ONPATTRO (patisiran) lipid complex injection.
Transthyretin amyloidosis is a rare disease and its symptoms are not easily identified. It is therefore, diagnosed late, which in turn affects the course of action in terms of treatment. According to the data published by The American Journal of Managed Care in 2017, hereditary transthyretin-mediated (hATTR) amyloidosis affects around 50,000 patients worldwide. However, the diagnosis rate of disease is very low. According to the study published by Alnylam Pharmaceuticals, Inc., in January 2018, the diagnosis rate of hATTR in the U.S. is around ~10-30%, which is expected to be a major factor restraining growth of the market over the forecast period.
Key Takeaways of the Global Transthyretin Amyloidosis Treatment Market:
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