CRISPR and CAS Gene Market, By Product Type (Vector-based Cas and DNA-free Cas), By Application (Genome Engineering, Disease models, Functional Genomics, Knockdown/activation and Other Applications), By End User (Biotechnology and Pharmaceutical Companies, Academic Government Research Institutes, and Contract Research Organizations), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2018 - 2026

  • Published On : May 2019 |
  • Pages : 206 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

CRISPR and CAS Gene Market – Insights

CRISPR technology is a simple yet powerful nucleic acid-targeting editing tools for genome. It allows researchers to easily alter DNA sequences and modify gene function. It has many potential applications, which include correcting genetic defects, treating and preventing the spread of diseases, and improving crops. It is faster, cheaper, and more accurate than previous techniques of editing DNA like ZFNs (Zinc Finger Nucleases) and TALENs (Transcription Activator-Like Effector Nucleases). And has a wide range of potential applications. Researchers are focusing on its use in animal models or isolated human cells, with the aim to eventually use the technology for routinely treating diseases in humans.

The global CRISPR and CAS Gene market size was valued at US$ 1,388.1 million in 2017, and is expected to witness a CAGR of 20.8% over the forecast period (2018 – 2026).

Global CRISPR and CAS Gene Market Share (%) Analysis, By Product Type, 2017

CRISPR & CAS Gene  | Coherent Market Insights

Source: Coherent Market Insights Analysis (2019)

Increasing Demand for Clinical Trials Coupled with Increasing Research & Development in CRISPR and CAS Gene therapy is expected to Drive Growth of the CRISPR and CAS Gene Market           

Increasing research & development and demand for clinical trials for development of new technologies in CRISPR and CAS gene therapy for treatment of cancer is one of the major driving factor. For instance, The Parker Institute for Cancer Immunotherapy, a non-profit organization formed in April 2016, with a US$ 250 million grant from the Parker Foundation, agreed to sponsor the first in-human clinical trials of CRISPR-enabled technology targeting three types of cancer. The trial, led by the University of Pennsylvania, will use CRISPR-modified T-cells, a part of the human immune system, to treat myeloma, melanoma, and sarcoma. The trial was commenced in 2017.

Therefore, increasing research on CRISPR and CAS gene market is expected to create a favorable environment for CRISPR and CAS gene market growth in the near future.

CRISPR and CAS Gene Market – Restraints

The major restraining factor for the CRISPR and CAS gene market growth are the ethical and safety issues about the CRISPR and CAS gene therapy for gene editing and creating genetically modified (GM) food or organism. In 2015, the US Food and Drug Administration (FDA) prohibited funding bills considering application of CRISPR and CAS gene technology to create IVF children from embryos that have been genetically modified.

CRISPR and CAS Gene Market - Regional Insights

On the basis of region, the global CRISPR and CAS Gene market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold a dominant position in the global CRISPR and CAS Gene market, owing to increasing number of the Food and Drug Administration (FDA) approval for clinical trial. For instance, in October 2018, CRISPR Therapeutics and Vertex Pharmaceuticals' highly anticipated gene-editing trial, which was allowed for the first time to discover, develop, and commercialize new breakthrough therapeutics to cure blood disorders and congenital heart disease using the CRISPR/Cas9 technology in the U.S.  In January 2019, CRISPR Therapeutics and Vertex Pharmaceuticals’ have been granted Fast Track Designation to CTX001 for the treatment of sickle cell disease (SCD) by FDA. CTX001 is an investigational, autologous, gene-edited hematopoietic stem cell therapy for patients suffering from severe hemoglobinopathies.

Asia Pacific is expected to foresee a rapid growth in the CRISPR and CAS Gene market over the forecast period. The market in Asia Pacific is expected to gain momentum during the forecast period, owing to rise in the demand of CRISPR and CAS gene therapy especially in research activities. For instance, in May 2018 researchers at Kobe University in Japan successfully destroyed and deleted the regulatory genes of HIV-1 using the genome editing system CRISPR/Cas9, thereby successfully blocking the production of HIV-1 by infected cells.

Global CRISPR and CAS Gene Market Value (US$ Mn) & Y-o-Y Growth (%), 2016-2026

   CRISPR & CAS Gene  | Coherent Market Insights

 Source: Coherent Market Insights Analysis (2019)

CRISPR and CAS Gene Market - Competitive Landscape

Key players operating in the global CRISPR and CAS Gene market include Caribou Biosciences Inc., CRISPR Therapeutics, Mirus Bio LLC, Editas Medicine, Takara Bio Inc., Synthego, Thermo Fisher Scientific, Inc., GenScript, Addgene, Merck KGaA (Sigma-Aldrich), Integrated DNA Technologies, Inc., Transposagen Biopharmaceuticals, Inc., OriGene Technologies, Inc., New England Biolabs, Dharmacon, Cellecta, Inc., Agilent Technologies, and Applied StemCell, Inc.

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and CRISPR-associated (Cas) genes are essential for the adaptive immunity in few bacteria and archaea, enabling the organisms to respond to and to eliminate invading genetic material. These gene editing tools are extensively used in agriculture and food security.

Many food and agricultural organizations are working on receiving license for using CRISPR and CAS gene technology for creating novel products in food and agriculture business. For instance, in September 2016, agrochemical and agricultural biotechnology corporation Monsanto secured a worldwide non-exclusive license agreement for agricultural applications of CRISPR technology from the Broad Institute. CRISPR and CAS genes are also used in treating a number of diseases such as cancer, blood disorders, AIDS, and genetic disorders such as cystic fibrosis, Huntington’s etc.

Market Dynamics

Increasing prevalence of genetic disorders such as Down’s syndrome, sickle cell anaemia, and Huntington’s disease worldwide is highly contributing to the market growth of CRISPR and CAS gene market, as many genetic disabilities can be corrected using this gene editing technology. According to National Health Service (NHS) U.K. 2018 report, the highest rate of Huntington’s disease in the United Kingdom is 12 per 100,000 people. Also, in the U.S., an estimated 10 per 100,000 have the faulty Huntington’s gene and live either waiting for symptoms to begin or live/struggle with the disease.

Government bodies are taking initiatives for developing treatment of Huntington’s disease. For instance, in 2016, US-based Company Addgene has developed the KamiCas9, a version of CRISPR-Cas9 that includes a ‘self-inactivating’ KamiCas9 system for the editing of CNS disease genes for treatment of Huntington’s disease.

However, the CRISPR and CAS gene market growth is hindered by the ethical issues, which is the major concern for every gene therapy. For instance, in April 2015, the US National Institutes of Health issued a statement indicating that it will not fund any research that uses genome editing tools such as CRISPR in human embryos due to ethical issues.

Key features of the study:

  • This report provides in-depth analysis of the CRISPR and CAS Gene market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2019 – 2026, considering 2018, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles key players in the global CRISPR and CAS Gene market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Caribou Biosciences Inc., CRISPR Therapeutics, Mirus Bio LLC, Editas Medicine, Takara Bio Inc., Synthego, Thermo Fisher Scientific, Inc., GenScript, Addgene, Merck KGaA (Sigma-Aldrich), Integrated DNA Technologies, Inc., Transposagen Biopharmaceuticals, Inc., OriGene Technologies, Inc., New England Biolabs, Dharmacon, Cellecta, Inc., Agilent Technologies, and Applied StemCell, Inc.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The global CRISPR and CAS Gene market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors, and suppliers for CRISPR and CAS Gene market, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Global CRISPR and CAS Gene Market, By Product Type:
    • Vector-based Cas
    • DNA-free Cas
  • Global CRISPR and CAS Gene Market, By Application:
    • Genome Engineering
    • Disease models
    • Functional Genomics
    • Knockdown/activation
    • Other Applications
  • Global CRISPR and CAS Gene Market, By End User:
    • Biotechnology and Pharmaceutical Companies
    • Academic & Government Research Institutes
    • Contract Research Organizations
  • Global CRISPR and CAS Gene Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas            
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas            
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Product Type:
        • Vector-based Cas
        • DNA-free Cas
      • By Application:
        • Genome Engineering
        • Disease models
        • Functional Genomics
        • Knockdown/activation
        • Other Applications
      • By End User:
        • Biotechnology and Pharmaceutical Companies
        • Academic and Government Research Institutes
        • Contract Research Organizations
  • Company Profiles
    • Caribou Biosciences Inc.*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • CRISPR Therapeutics
    • Mirus Bio LLC
    • Editas Medicine
    • Takara Bio Inc.
    • Synthego Corporation
    • Thermo Fisher Scientific, Inc.
    • GenScript
    • Addgene
    • Merck KGaA (Sigma-Aldrich)
    • Integrated DNA Technologies, Inc.
    • Transposagen Biopharmaceuticals, Inc.
    • OriGene Technologies, Inc.
    • New England Biolabs
    • Dharmacon, Cellecta, Inc.
    • Agilent Technologies
    • Applied StemCell, Inc.

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Regulatory Landscape
    • Epidemiology Analysis
    • Technology Overview
    • PEST Analysis
    • Porter’s Five Forces model
  4. Global CRISPR and CAS Gene Market, By Product Type, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Vector-based Cas
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • DNA-free Cas
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  5. Global CRISPR and CAS Gene Market, By Application, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Genome Engineering
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Disease models
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Functional Genomics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Knockdown/activation
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Other Applications
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  6. Global CRISPR and CAS Gene Market, By End User, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Biotechnology and Pharmaceutical Companies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Academic and Government Research Institutes
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Contract Research Organizations
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  7. Global CRISPR and CAS Gene Market, By Region, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2017 – 2026
      • Regional Trends
    • North America
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By End User, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Company Profiles
      • Caribou Biosciences Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • CRISPR Therapeutics
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Mirus Bio LLC
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Editas Medicine
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Takara Bio Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Synthego Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Thermo Fisher Scientific, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • GenScript
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Addgene
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Merck KGaA (Sigma-Aldrich)
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Integrated DNA Technologies, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Transposagen Biopharmaceuticals, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • OriGene Technologies, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • New England Biolabs
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Dharmacon, Cellecta, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Agilent Technologies
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Applied StemCell, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 31 market data tables and 27 figures on " CRISPR and CAS Gene Market” - Global forecast to 2026”

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