ISOTHERMAL NUCLEIC ACID AMPLIFICATION TECHNOLOGY (INAAT) MARKET ANALYSIS

Global isothermal nucleic acid amplification technology (INAAT) market is estimated to be valued at US$ 2,490.2  Million in 2023, exhibiting a CAGR of 8.4% during the forecast period (2023-2030).

Analysts’ Views on Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market:

Global isothermal nucleic acid amplification technology (INAAT) market growth can be hindered by lack of awareness regarding new diagnostics technologies. Increasing approvals from healthcare regulatory authorities for innovative technologies is expected to drive the global isothermal nucleic acid amplification technology (INAAT) market growth over the forecast period. For instance, in March 2022, Thermo Fisher Scientific, Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services., launched its Invitrogen Super Script IV RT-LAMP Master Mix that can be used for the detection of various viral pathogens. Such product launches are boosting the market growth by increasing the utility of INAAT techniques.

Figure 1. Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market Share (%), By Product Type, 2023

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market– Driver

Increasing Approvals From Healthcare Regulatory Authorities For Innovative Technologies

Increasing approvals from healthcare regulatory authorities for innovative technologies by key market players is expected to drive the global isothermal nucleic acid amplification technology (INAAT) market growth over the forecast period. For instance, in 2022, according to the article published in the Analyst Journal , LAMP technology used showed how a smartphone-integrated equipment could quickly test for the Zika virus in a single blood drop. Such advances are probably going to increase the technique's market penetration in the near future.

Figure 2. Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market Value (US$ Million), By Region, 2023

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Regional Analysis

Among region, North America is estimated to hold a dominant position in the global isothermal nucleic acid amplification technology (INAAT) market over the forecast period. North America holds 43.3% of the market share, due to increasing prevalence of  chronic diseases in the region. For instance, in 2020,  according to Centers for Disease Control and Prevention (CDC), the total number of Americans with chronic diseases was 157 million, with 81 millionSimilarly, according to GLOBOCAN 2020, 2,281,658 new cancer cases were diagnosed in the U.S., in 2020, with 612,390 fatalities.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.

COVID-19 affected the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, the U.A.E., Egypt, and others faced problems regarding transportation of drugs from one place to another.

However, the COVID-19 pandemic had a positive impact on the global isothermal nucleic acid amplification technology (INAAT) market growth, owing to increasing usage of and product approvals and launches of  isothermal nucleic acid amplification technology during the pandemic. For instance, in March 2020, Abbott company provides from newborns to aging adults, from nutrition and diagnostics through medical care and pharmaceutical therapy. , received the U.S. Food and Drug Administration approval for the emergency use of ID NOW COVID-19, an instrument-based, isothermal, rapid system for the qualitative finding of disease.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Segmentation

Global isothermal nucleic acid amplification technology (INAAT) market is segmented into product type, technology, application, end user, and region.

Based on Product Type, the market is segmented into instruments and reagents and kits. Out of which, the reagents and kits  segment is expected to hold a dominant position in the global isothermal nucleic acid amplification technology (INAAT) market during the forecast period, owing to increasing usage of reagents and kits. 

Based on Application, the market is segmented into infectious disease diagnostics, blood screening, and others. Out of which, the infectious disease diagnostics segment is expected to dominate the market over the forecast period, owing to rising number of infectious disease.

Based on Technology, the market is segmented into helicase dependent amplification (HAD), nicking enzyme amplification reaction (NEAR), nucleic acid sequence based amplification (NASBA), transcription medicated amplification (TMA), single primer isothermal amplification (SPIA), and loop-mediated isothermal amplification (LAMP). Out of which, the loop-mediated isothermal amplification (LAMP) segment is expected to hold a dominant position in the global isothermal nucleic acid amplification technology (INAAT) market during the forecast period, owing to increasing product launches by the key players.

Based on End User, the market is segmented into academic and research institutes, diagnostic laboratories, and others. Out of which, the diagnostic laboratories segment is expected to dominate the market over the forecast period, owing to increasing number of the tests in laboratories.

Among all segmentation, the product type segment has the highest potential due to increasing usage of reagents and kits  over the forecast period. For instance, The RT-LAMP protocol includes reagents for fast and simple testing and surveillance of viral pathogens including SARS-CoV-2. The workflow is easy to set-up, with a fast turnaround time, and only requires a simple heat source to maintain a constant temperature.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Cross Sectional Analysis

Among technology, the loop-mediated isothermal amplification (LAMP) segment is dominant in Asia Pacific region during the forecast period, owing to increasing prevalence of chronic disease such as malaria other pandemic diseases in regions such as East and South Asia.For instance, China is expected to dominate the market due to rise in prevalence of chronic diseases and geriatric population along with increase in per capita income.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Key Developments

• In May 2022, Hologic, Inc. is a medical technology company primarily focused on women’s health; it sells medical devices for diagnostics, surgery, and medical imaging., received CE marking for two new molecular assays named Panther Fusion EBV Quant Assay and Panther Fusion BKV Quant Assay, expanding its transplant pathogen monitoring product portfolio on the Panther Fusion system.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Key Trends

Increasing Product Launches

Increasing product launch of loop-mediated isothermal amplification for the isothermal nucleic acid amplification technology is expected to drive the global isothermal nucleic acid amplification technology market growth over the forecast period. For instance, in May 2022, Meridian Bioscience is a life science company that develops, manufactures, markets, and distributes a broad range of innovative diagnostic and life science products., launched two new innovative isothermal amplification products named Lyo-Ready Direct DNA LAMP Saliva Mix and Lyo-Ready Direct RNA/DNA LAMP saliva mix. These are used for direct detection of DNA and RNA in point of care dagnostics assays.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market- Restraint

High Cost of Technology 

Global isothermal nucleic acid amplification technology (INAAT) market growth can be hindered by high cost of the technology of the loop-mediated isothermal amplification (LAMP). For instance, Due to the advanced technology, the costs of loop-mediated isothermal amplification are high. As a result, the population with middle income is anticipated to push themselves away from adopting the technique.

Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market - Key Players

Major players operating in the global isothermal nucleic acid amplification technology (INAAT) market include Alere Inc., Becton, Dickinson & Company, BioHelix Corporation, BioMerieux Biotechnology Company, Hologic Gene-Probe, QIAGEN Company, Thermo Fisher Scientific, Inc., Lucigen Corporation, Quidel Corporation, and NuGEN.

*Definition: Nucleic acid sequence-based amplification is a type of method in molecular biologythat is used to amplify RNA sequences. Isothermal nucleic acid amplification technology (INAAT) is segregated into several methods such as transcription mediated amplification, nucleic acid sequence-based amplification, signal mediated amplification of RNA technology, and others. Such methods of isothermal nucleic acid amplification technology are usedto amplify RNA sequences.