Nucleic acid sequence-based amplification is a type of method in molecular biology, which is used to amplify RNA sequences. Isothermal Nucleic acid Amplification Technology (INAAT) is segregated into several methods such as transcription mediated amplification, nucleic acid sequence-based amplification, signal mediated amplification of RNA technology, and others. Such methods of isothermal nucleic acid amplification technology to amplify RNA sequences are expected to rapidly drive the growth of the market during the forecast period.
The global isothermal nucleic acid amplification technology (INAAT) market was valued at US$ 1,763.0 million in 2018 and is expected to exhibit a CAGR of 8.3% during the forecast period (2019-2027).
Figure 1. Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market Share (%), by Product Type
-market-fig-1.png "Isothermal Nucleic Acid Amplification Technology | CMI")
(Source: Coherent Market Insights, 2020)
Manufacturers are engaged in adopting inorganic growth strategies such as collaborations, and mergers and acquisitions to enhance their product portfolio and strengthen their position in the market
The increasing collaboration activities by key players is expected to boost the global isothermal nucleic acid amplification technology (INAAT) market growth. For instance, in January 2017, Diagenode S.A. entered into a collaboration with Heidelberg University Hospital and German Cancer Research Center (DKFZ). Under this collaboration, Diagenode S.A focuses on development of high-sensitivity DNA amplification method. This method is for RNA sequencing library preparation solutions.
Key players in the market are focused on product launches for molecular diagnosis, which is expected to propel the global isothermal nucleic acid amplification technology (INAAT) market growth
For instance, in April 2019, QuantaBio launched new freeze-dried lyophilized single-reaction reagent, Qscript lyo 1-step. Qscript lyo 1-step is a dry, stable, easy, and better 1-step RT-qPCR (quantitative reverse transcription polymerase chain reaction). It is highly sensitive and reproducible RT-qPCR. The reagent contains thermo-stable polymerase.
Isothermal Nucleic Acid Amplification Technology (INAAT) Market - Regional Analysis
North America isothermal nucleic acid amplification technology (INAAT) market is expected to account for the largest market share during the forecast period, owing to increasing product launches by key players. For instance, in September 2017, Bio-Rad Laboratories, Inc. launched RT-PCR (reverse transcriptase-polymerase chain reaction) kit in the U.S market. RT-PCR assay kit is a one-step procedure, where reverse transcription and gene amplification is performed in a single tube. RT-PCR assay kit is used for DNA identification and amplification.
Moreover, Europe is also expected to witness significant growth in the global isothermal nucleic acid amplification technology (INAAT) market, owing to increasing product launches in the region. For instance, in December 2019, Mast Group Ltd., a European company, launched MAST ISOPLEX CRE-ART kit, which uses loop mediated amplification (LAMP) kit for the rapid molecular detection of the most seven prevalent carbapenemase families: OXA-48, OXA-23, OXA-24/40, KPC, VIM, NDM and IMP. The carbapenemase family involves enterobacteriaceae (E.coli, Salmonella, Klebsiella, and Shigella), where some of them reside in the gut of humans while the remaining are parasites.
INAAT offers advantage over the conventional detection system by detecting the test sample in 30 minutes run time and availability of ready to use lyophilized pellets containing primers and reagents, which are used directly for the reaction, therefore the sample preparation process is completely eliminated. The above factors are expected to fuel the global isothermal nucleic acid amplification technology market growth over the forecast period.
Figure 2: Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market Value (US$ Mn), By Region
-market-fig-2.png "Isothermal Nucleic Acid Amplification Technology | CMI")
(Source: Coherent Market Insights, 2020)
Global Isothermal Nucleic Acid Amplification Technology (INAAT) Market - Competitive Landscape
Key players operating in the isothermal nucleic acid amplification technology (INAAT) market include Alere Inc., Becton, Dickinson & Company, BioHelix Corporation, BioMerieux Biotechnology Company, Hologic Gene-Probe, QIAGEN Company, Thermo Fisher Scientific, Inc., Lucigen Corporation, Quidel Corporation, and NuGEN.
Isothermal nucleic acid technologies have applications in the field of recombinant DNA and molecular biology techniques. These techniques are used in the detection and analysis of small quantity of nucleic acids. Polymerase chain reaction is based on isothermal nucleic acid amplification technology. The polymerase chain reaction (PCR) is most widely used method for DNA amplification. Polymerase chain reaction (PCR) is used for the detection and identification of infectious diseases, genetic disorders, and for research purposes. PCR consists of thermocycling machine, which facilitates separation and amplification of DNA strands.
Market Dynamics
Increasing approvals from healthcare regulatory authorities for innovative technologies is expected to drive the global isothermal nucleic acid amplification technology (INAAT) market growth
For instance, in October 2018, Abbott laboratories received the U.S. Food and Drug Administration (FDA) for its next-generation Influenza A & B2 and Strep A2 molecular assays. These assays are used for the molecular detection and differentiation of influenza A and B virus. Next-generation Influenza A & B2 and Strep A2 molecular assays are currently available on ID NOW platform, which is a rapid isothermal system. It is used for the detection of infectious diseases such as influenza.
Rising product launches by key players is expected to boost the global isothermal nucleic acid amplification technology (INAAT) market growth
For instance, in July 2017, TwistDx Inc. launched TwistAmp, a recombinase polymerase amplification (RPA) kit. It is used for DNA/RNA amplification. TwistAmp is an isothermal alternative to polymerase chain reaction PCR.
Key features of the study:
Detailed Segmentation:
“*” marked represents similar segmentation in other categories in the respective section.
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