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Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

Electroporation is a useful molecular biology technique that allows for non-chemical transformation of bacteria and yeasts as well as transfection of tissue culture cells (e.g. mammalian cells). Electroporation systems deliver short bursts of a high-intensity electric field to cells. The electrical field makes the cell membrane more permeable. As a result, chemicals such as drugs and genetic material can pass through the cell membrane, which would otherwise be impermeable. Due to its ease of use and efficacy, electroporation is a popular method for introducing foreign genes into target cells.

In addition to direct gene introduction, electroporation allows for the direct transfer of plasmids between cells or species—for instance, from bacteria to yeast. Extensive research is ongoing on the use of electroporation to deliver medicines and vaccines directly to the cells of living organisms.

Electroporation systems are commonly used for the treatment of cancer through vaccine delivery, gene delivery or drug delivery that is electro-chemotherapy, for instance bleomycin. Vaccine delivery can also be used for treatment of infectious disease such as Human immunodeficiency virus (HIV).

Global Electroporation Instruments Market - Impact of the Coronavirus (COVID-19) Pandemic

Coronavirus (COVID-19) outbreak was first reported on December 31, 2019, in Wuhan, China. The World Health Organization declared COVID-19 as pandemic on March 11, 2020. According to the Coronavirus (COVID-19) Weekly Epidemiological Update by the World Health Organization, over 195 million cases and 4.19 million deaths due to coronavirus disease (COVID-19) were reported till July 29, 2021, across the globe.

Impact of COVID-19 on Demand and Supply of Electroporation Instruments

The COVID-19 pandemic and lockdown in various countries across the globe has impacted the financial status of businesses across all sectors including private healthcare sector. The COVID-19 pandemic has impacted the entire supply chain of the healthcare industry mainly due to strict lockdown in several regions. The COVID-19 pandemic has affected the economy of various regions across the globe in three main ways; 1) by directly affecting the production and demand; 2) by creating disruptions in distribution channels; and 3) through its financial impact on companies and financial markets. Several countries such as Thailand, Indonesia, and Singapore are facing problems with regards to transportation and distribution of healthcare products.

However, the COVID-19 pandemic might have a positive impact and boost the growth of the global electroporation instruments market over forecast period, owing to the use of electroporation in delivering of vaccines and drugs for the treatment of COVID-19. For instance, according to news article published in Eureka, blog of Charles River Laboratories Inc., U.S. on January 13, 2021, as the race for a COVID-19 vaccine intensified, researchers began looking for better, more effective drug delivery systems. Electroporation is one such in vivo drug delivery technology (EP). It has been demonstrated that electroporation has a significant impact on vaccine immunogenicity and efficacy. This is due to the fact that it has the potential to increase antigen delivery by up to 1000-fold when compared to naked DNA delivery technologies alone. The increase in antigen  delivery results in a greater magnitude of immune response as well as higher response rates when compared to DNA delivery via direct injection alone.

The global electroporation instruments market is estimated to be valued at US$ 769.0 Mn in 2021, and is expected to exhibit a CAGR of 4.4 % over the forecast period (2021-2028).

Figure 1: Global Electroporation Instruments Market Share (%) Analysis, By Product Type (Instruments), 2021

Electroporation Instruments  | Coherent Market Insights

As electroporation is used to treat various cancers, the prevalence of cancer is the major factor that is expected to drive the growth of global electroporation instruments market over the forecast period.

The emerging prevalence of cancers is expected to bolster the growth of global electroporation instruments market as electroporation helps in the treatment of cancers. For instance, according to the World Health Organization report 2020, cancer is the leading cause of death in the world, accounting for nearly ten million deaths in 2020. In terms of new cancer cases worldwide, the most common were: 2.26 million cases of breast cancer, 2.21 million cases of lung cancer, 1.4 million cases of prostate, 1.20 million cases of skin, 1.93 million cases of coon & rectum, and 1.09 million cases of stomach.

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Electroporation Instruments Market Report Coverage

Report Coverage Details
Base Year: 2020 Market Size in 2021: US$ 769.0 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2021 to 2028
Forecast Period 2021 to 2028 CAGR: 4.4 % 2028 Value Projection: US$ 1,036.6 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Product Type: Instruments (Total Electroporation System, Transfection System, Microbial Electroporation System), Accessories (Electroporated Cuvettes, Electrodes, Volume Chambers, Others)
  • By Application: Protein Production, Therapeutic Delivery, Biomedical Research
  • By End User: Hospital Laboratories, Research & Academic Institutes, Biotechnology or Pharmaceutical Industries
Companies covered:

Bio-Rad Laboratories, Thermo Fisher Scientific, Inc., Harvard Bioscience Inc. (BTX), Celetrix LLC, Mirus Bio LLC, Merck KGaA, Eppendorf AG, MaxCyte Inc., BEX Co. Ltd., and Lonza Group

Growth Drivers:
  • Increasing cases of cancer
  • Increasing partnerships and agreements within market players
  • Increasing product launches and approvals

Agreements, Partnerships, and Acquisition

Market players are adopting strategies such as agreements, partnerships or acquisitions which is expected to aid in the growth of the global electroporation instruments market over the forecast period. For instance, on June 16, 2020, Immunomic Therapeutics Inc., a privately held clinical-stage biotechnology company, entered into a license agreement with Ichor Medical Systems, a privately held biotechnology company based in California, U.S., to use Electroporation (EP) Delivery Technology in the Phase I study of ITI-1001, a DNA vaccine therapy. When administered to patients with newly diagnosed Glioblastoma, or GBM, Ichor's TriGrid Electroporation technology will help in increasing the cellular uptake of ITI-1001 which is in development by Immunomic Therapeutics.

Global Electroporation Instruments Market – Regional Analysis

On the basis of region, the global electroporation instruments market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

Among regions, North America is expected to hold dominant position in the global electroporation instruments market over the forecast period, owing to the launches and approvals of electroporation systems. For instance, on October 15, 2020, Precigen Inc., a biopharmaceutical company, announced the U.S. Food and Drugs Administration (FDA) clearance and successful technology transfer for its UltraPorator system, a high-throughput, semi-closed electroporation system for reprograming T-cells that uses Precigen's Sleeping Beauty non-viral gene transfer technology. In accordance with current good manufacturing practices (cGMP), the U.S. FDA approved UltraPorator as a manufacturing device for clinical trials of Precigen's investigational UltraCAR-T therapies.

Moreover, Europe is expected to witness a significant growth in global electroporation instruments market over the forecast period, owing to the launches and approvals of electroporation systems. For instance, on April 14, 2021, OncoSec Medical Inc., a biotechnology company focused on cytokine-based intratumoral immunotherapies, announced that it has been granted CE (European conformity) marking for its proprietary next generation go-to-market gene delivery device, GenPulse, which is part of the OncoSec Medical System (OMS) electroporation device platform for use in solid tumors. CE marking denotes that a product has been evaluated by the manufacturer and found to meet European Union (EU) safety, health, and environmental protection standards.

Figure 2: Global Electroporation Instruments Market Value (US$ Mn), By Region, 2021

Electroporation Instruments  | Coherent Market Insights

Global Electroporation Instruments Market – Competitive Landscape

Major players operating in the global electroporation instruments market include Bio-Rad Laboratories, Thermo Fisher Scientific, Inc., Harvard Bioscience Inc. (BTX), Celetrix LLC, Mirus Bio LLC, Merck KGaA, Eppendorf AG, MaxCyte Inc., BEX Co. Ltd., and Lonza Group.

Electroporation is used to introduce macromolecules such as proteins into cells, either in vivo or in vitro, by using brief electric pulses that cause momentary and reversible permeabilization of the cell membrane.

Electroporation of biological membranes has a wide range of applications in molecular biology and medicine such as intravascular drug and gene delivery using electroporation catheters, electro-insertion of molecules into membranes, intraocular drug and gene delivery, and transdermal drug delivery. Several in-vitro and in-vivo experimental studies have been carried out to determine the mechanisms of electroporation action in various types of membranes.

Electroporation has also proven to be a promising technique for targeted drug delivery in cancer therapy.

Market Dynamics

Market players are involved in research and development activities related to electroporation devices, this could contribute to the growth of the global electroporation instruments market over the forecast period. For instance, on April 02, 2019, OncoSec Medical Inc., an enterprise growing novel cancer immunotherapies based in New Jersey, U.S., presented pre-clinical data highlighting its novel anti-tumor product candidate, SPARK, and its advanced electroporation generator, APOLLO in a poster presentation at the 2019 American Association for Cancer Research (AACR) Annual Meeting in Atlanta, Georgia. The poster, entitled, "Intratumoral electroporation of plasmid IL-12 and CXCL9 with membrane-bound anti-CD3 elicits robust anti-tumor immunity," provided new preclinical statistics demonstrating strong anti-tumor responses driven by way of considerable improvements made to OncoSec's proprietary cancer immunotherapy platform.

Market players focusing on clinical agreements is expected to strengthen their position in the global electroporation instruments market. For instance, on October 07, 2019, MaxCyte, Inc., a global cell-based therapies and life sciences company based in Maryland U.S., and Editas Medicine Inc., a leading genome editing company based in Massachusetts, U.S., announced a new clinical and commercial license agreement. Editas Medicine will advance engineered cell medicines using MaxCyte's Flow Electroporation technology and ExPERT instruments, including EDIT-301, an experimental CRISPR medicine designed to treat sickle cell disease and beta-thalassemia indefinitely.

Market players are involved in expanding their global presence by adopting strategies such as acquisitions and partnerships, which is expected to drive the growth of the global electroporation instruments market. For instance, on January 19, 2021, Sirtex Medical U.S. Holdings Inc., a leading manufacturer of targeted cancer therapies, announced a step forward in its strategic collaboration with OncoSec Medical Inc., a biotechnology company, relating to OncoSec's lead product candidate TAVO (tavokinogene telseplasmid) and its electroporation (EP) gene delivery system. Sirtex after the collaboration has the option to acquire the right to co-promote TAVO in the U.S. and its related EP gene delivery system in the lead indication of treating anti-PD-1 refractory locally advanced or metastatic melanoma.

Key features of the study:

  • This report provides an in-depth analysis of global electroporation instruments market, provides market size (US$ Million), and compound annual growth rate (CAGR %) for the forecast period (2021-2028), considering 2020 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategies adopted by the leading players
  • It profiles leading players in the global electroporation instruments market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies, and future plans
  • Key companies covered as a part of this study include Bio-Rad Laboratories, Thermo Fisher Scientific, Inc., Harvard Bioscience Inc. (BTX), Celetrix LLC, Mirus Bio LLC, Merck KGaA, Eppendorf AG, MaxCyte Inc., BEX Co. Ltd., and Lonza Group
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
  • The global electroporation instruments market report caters to various stakeholders in this industry including investors, suppliers, manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision making through various strategy matrices used in analyzing the global electroporation instruments market

Detailed Segmentation:

  • Global Electroporation Instruments Market, By Product Type:
    • Instruments
    • Total Electroporation System
    • Transfection System
    • Microbial Electroporation System
    • Accessories
    • Electroporated Cuvettes
    • Electrodes
    • Volume Chambers
    • Others
  • Global Electroporation Instruments Market, By Application:
    • Protein Production
    • Therapeutic Delivery
    • Biomedical Research
  • Global Electroporation Instruments Market, By End User:
    • Hospital Laboratories
    • Research & Academic Institutes
    • Biotechnology or Pharmaceutical Industries
  • Global Electroporation Instruments Market, By Region:
    • North America
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Product Type:
        • Instruments
        • Total Electroporation System
        • Transfection System
        • Microbial Electroporation System
        • Accessories
        • Electroporated Cuvettes
        • Electrodes
        • Volume Chambers
        • Others
      • By Application:
        • Protein Production
        • Therapeutic Delivery
        • Biomedical Research
      • By End User:
        • Hospital Laboratories
        • Research & Academic Institutes
        • Biotechnology or Pharmaceutical Industries
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Bio-Rad Laboratories*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Developments/Updates
      • Strategies
    • Thermo Fisher Scientific Inc.
    • Harvard Bioscience Inc. (BTX)
    • Celetrix LLC
    • Mirus Bio LLC
    • Merck KGaA
    • Eppendorf AG
    • MaxCyte Inc.
    • BEX Co. Ltd.
    • Lonza Group.

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Porter’s Analysis
    • Industry Trends
    • Key Highlights
    • Epidemiology
    • Reimbursement Scenario
    • Regulatory Scenario
    • Product Launch and Approvals
    • Acquisition and Collaboration Scenario
  4.  Global Electroporation Instruments  Market - Impact of Coronavirus (Covid-19) Pandemic
    • COVID-19 Epidemiology
    • Impact of COVID-19 on Demand and Supply of Electroporation Instruments
    • Impact of COVID-19 on the overall Healthcare Sector
  5. Global Electroporation Instruments Market, By Product Type, 2017 - 2028 (US$ Million)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2018 - 2028
      • Segment Trends
    • Instruments
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Total Electroporation System
    • Transfection System
    • Microbial Electroporation System
    • Accessories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Electroporated Cuvettes
    • Electrodes
    • Volume Chambers
    • Others
  6. Global Electroporation Instruments Market, By Application, 2017 - 2028 (US$ Million)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2018 - 2028
      • Segment Trends
    • Protein Production
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Therapeutic Delivery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Biomedical Research
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
  7. Global Electroporation Instruments Market, By End User, 2017 - 2028 (US$ Million)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2018 - 2028
      • Segment Trends
    • Hospital Laboratories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Research & Academic Institutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
    • Biotechnology or Pharmaceutical Industries
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2028, (US$ Million)
  8. Global Electroporation Instruments Market, By Region, 2017 - 2028 (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, For Regions, 2018 - 2028
      • Regional Trends
    • North America
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By End User, 2017 - 2028 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2017 - 2028 (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  9. Competitive Landscape
    • Company Profiles
      • Bio-Rad Laboratories*
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Thermo Fisher Scientific Inc.
      • Harvard Bioscience Inc. (BTX)
      • Celetrix LLC
      • Mirus Bio LLC
      • Merck KGaA
      • Eppendorf AG
      • MaxCyte Inc.
      • BEX Co. Ltd.
      • Lonza Group

*Key pointers provided are also applicable to other companies covered in the scope of the report.

    • Analyst Views
  1. Section
    • Research Methodology
    • About us
    • Contact

*Browse 33 market data tables and 25 figures on “Electroporation Instruments Market” - Global Forecast to 2028.

FAQgrowicon

Frequently Asked Questions

The global electroporation instruments market is expected to exhibit a CAGR of 4.4% during the forecast period (2021-2028).
The market is estimated to be valued at US$ 769.0 Mn in 2021.
Bio-Rad Laboratories, Thermo Fisher Scientific, Inc., Harvard Bioscience Inc. (BTX), Celetrix LLC, Mirus Bio LLC, Merck KGaA, Eppendorf AG, MaxCyte Inc., BEX Co. Ltd., and Lonza Group are some of the prominent players operating in the market.
The market is expected to be valued at US$ 1,036.6 Mn in 2028.
North America is the prominent region in the market.
Increasing cases of cancers, increasing partnerships and agreements by market players, and increasing product launches and approvals are some of the driving factors which are expected to drive growth of the market.
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