FOOT AND MOUTH DISEASE VACCINE MARKET ANALYSIS

Vaccination of susceptible animals against foot-and-mouth disease (FMD) is a well-established strategy for helping to combat the disease. Traditionally, FMD vaccine has been used to control a disease incursion in countries where the disease has been endemic rather than in countries considered free of the disease. Foot and Mouth Disease (FMD) is an infectious disease, which majorly affects cattle, sheep, goats and swine. It is highly prevalent in regions such as Asia pacific, Latin America, Africa, Middle East and Eastern Europe. Foot and mouth disease is gaining significant traction due to its economic impact on food industry, as it affects milk and meat production. Therefore, FMD vaccines play important role in the prevention of the disease. Both oil-based and aluminum hydroxide adjuvants variety of Foot and Mouth Disease Vaccines are available. However, oil-based vaccine holds dominant position in the FMD vaccine market.

Global foot and mouth disease vaccine market is estimated to be valued at US$ 2,396.3 million in 2022 and is expected to exhibit a CAGR of 9.4% during the forecast period (2022-2030).

Figure 1. Global Foot and Mouth Disease Vaccine Market Share (%), by Animal Type, 2022

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Repetitive outbreak of foot and mouth diseases in animals negatively affecting economies is driving growth of the foot and mouth disease vaccine market.

Repetitive outbreak of foot and mouth diseases around world thereby causing economic and social damage. Preventing foot and mouth disease is the only sustainable and viable option for animals to prevent from foot and mouth disease, which can be done only though the vaccination for FMD, which is expected to drive growth of the foot and mouth disease vaccine market. For instance, in March 2019, according to data published by Springer Nature, foot-and-mouth disease (FMD) is a major worldwide viral disease in animals, affecting the national and international trade of livestock and animal products and leading to high economic losses and social consequences. In cattle, buffalo and sheep (but not pigs), following the acute stage of infection, a high proportion of animals (e.g. about 50% of cattle) may become persistently infected with low levels of infectious virus present in the oropharynx. Hand, foot, and mouth disease (HFMD) is a serious disease burden in the Asia Pacific region. Although foot and mouth disease is eradicated from North America and Western Europe, various economies of Asia Pacific, Africa and Latin America witnessed high incidences of epidemic in 2017-2018, which is propelling demand for vaccines against foot and mouth disease in these regions.

Moreover, in June 2022, according to an article published by Faculty of Veterinary Medicine Universities foot and mouth disease (FMD) was detected in Indonesia in May 2022. Faculty of Veterinary Medicine, Universitas Gadjah Mada supports the government’s efforts to overcome this outbreak. As an educational institute, UGM held a national webinar about Foot and Mouth Disease Vaccine Development.

Figure 2.Global Foot and Mouth Disease Vaccine Market Share (%), by Region, 2022

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Increasing number of animal headcount worldwide is expected to drive growth of the foot and mouth disease vaccine market.

High animal density and increasing population of livestock animals is expected to be a major impetus for the growth of FMD vaccine market. According to U.S. Department of Agriculture data in 2017, India has cattle in number around 300 million, followed by Brazil and China. According to the factsheet by United Nations Food and Agriculture Organization (UN-FAO), worldwide there is close to one billion headcount of swine in 2017. China has highest number of swine headcount numbering 455 million. Infected animals can transmit infection to other animals if their movement is not restricted. Vaccination of animals for FMD prevents future risks and creates sustainable growth for animal population worldwide especially in a region, which is prone to FMD outbreak.

Global Foot and Mouth Disease Vaccine Market– Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization had declared it a public health emergency on January 30, 2020.

COVID-19 can affect the economy in three main ways: by directly affecting production and demand of other vaccines and drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries, such as China, India, Saudi Arabia, U.A.E., Egypt, and others, are facing problems with regard to the transportation of drugs from one place to another.

However, the COVID-19 pandemic had a negative impact on the global foot and mouth disease vaccine market, owing to key players operating in the Foot and Mouth Disease Vaccine are capitalizing on value-grab opportunities to develop COVID-19 (coronavirus) vaccines that hold promising potentials to protect animals. For instance, April 2020, researchers from Sinovac Biotech Ltd., based in China, Biopharmaceutical Company, gave two different doses of their COVID-19 vaccine to a total of eight rhesus macaques. Three weeks later, the group introduced SARS-CoV-2, the virus that causes COVID-19, into the monkeys' lungs through tubes down their tracheas, and none developed a full-blown infection.

Global Foot and Mouth Disease Vaccine Market: Key Developments

In March 2022, according to an article published by PubMed, a virology laboratory in Tunisia received the oral samples of cows suspected by veterinarians of having foot and mouth disease (FMD). After submission of the samples to a genetic sequencing service, Soufien Sghaier, a virologist at the Virology Laboratory at the Institute of Veterinary Research of Tunisia (IRVT), received results that helped confirm the circulating strain of foot and mouth disease. The timely confirmation was made possible by the International Atomic Energy Agency, in partnership with the Food and Agriculture Organization of the United Nations (FAO), which facilitated the sequencing service and provided the training needed to process the results. The Joint FAO/IAEA Centre launched its genetic sequencing service, available at no cost, in 2018 to enable countries to perform sequencing for in depth analysis of pathogens. Since then, more than 5 300 samples have been submitted by 30 laboratories from 24 countries across Africa, Asia Pacific, Europe and Latin America. African swine fever, astrovirus, avian influenza, capripox, coronavirus, lyssavirus, Newcastle disease, porcine circovirus 2, peste des petits ruminants and West Nile virus are the ten most frequent pathogens sequenced.

In June 2022, the national webinar was held at Faculty of Veterinary Medicine Universities Gadjah Mada as foot and mouth disease (FMD) was detected in Indonesia in May 2022. Faculty of Veterinary Medicine, Universitas Gadjah Mada supported the government’s efforts to overcome this outbreak. As an educational institute, UGM held a national webinar about foot and mouth disease vaccine development. This webinar was held online on Saturday, June 11, 2022. The main topic of this webinar was molecular epidemiology which emphasized the involvement of potential environmental and genetic risk factors, recognized at the molecular level, in the etiology and avoidance of sickness through populations of this foot-and-mouth disease. drh. Edy explained the role of Pusvetma as the main laboratory reference for foot-and-mouth disease in Indonesia and also about the vaccination program.

Global Foot and Mouth Disease Vaccine Market: Restraint

The major factors that hinder growth of the global foot and mouth disease vaccine market are that vaccination against foot and mouth disease may not prove to be effective by the antigenic diversity of the virus, the short-lived nature of protective immunity developed after vaccination and the temperature sensitivity that alters stability of foot and mouth disease vaccines. For instance, in June 2020, according to data published by National Center for Biotechnology Information, Advanced Foot-And-Mouth Disease Vaccine, the available commercial foot-and-mouth disease (FMD) vaccines have various limitations, such as the slow induction and short-term maintenance of antibody titers. Therefore, to overcome the limitations of currently existing FMD vaccines and to increase FMD vaccine efficacy, innovative solutions are required, such as immunopotent FMD vaccine strains and the development of new non-oil adjuvants (emulsions, immunostimulants, etc.) for application in FMD vaccines. These immunopotent FMD vaccine strains and non-oil adjuvants would increase the immunogenicity of the antigen itself, induce long-term protective antibodies and memory response, and simultaneously elicit robust cellular and humoral immune responses.

Key Players

Major players operating in the global foot and mouth disease vaccine market include Agrovet Indian Immunologicals Ltd., MSD Animal Health, Vallee SA, Bayer HealthCare, Brilliant Bio Pharma Ltd., Intervet, Biovet, Merial, China Animal Husbandry Co., Ltd., Biogénesis-Bagó S.A, Vetal Animal Health Products S.A.VETAL Animal Health Products, and Vecol S.A.