Impact Analysis of Covid-19

The complete version of the REPORT will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

Inactivated Polio and Rabies Vaccines Market – Insights

A vaccine consist of a biological preparation, which upon injection stimulates the immune system to secrete antibodies against the agent which is used to prepare vaccine. A vaccine is typically manufactured by using the disease-causing microorganism, which is weakened or killed to form a vaccine. Inactivated vaccine are type of vaccine, which are produced by growing the micro-organism (bacteria or viruses) on the culture medium, then inactivating them with heat and / or chemicals (formalin is mostly used for inactivation). Therefore, the components of the inactivated vaccine cannot replicate.

Moreover, the inactivated vaccine can be classified into two types such as whole killed vaccine and subunit vaccine. Moreover, when entire dose of inactivated vaccine is administered, the body elicits an immune response against the disease causing micro-organisms or viruses. Inactivated polio vaccine (IPV) and inactivated rabies vaccine (IRV) are most commonly used inactivated vaccine against polio and rabies, respectively, by global population.

The global inactivated polio and rabies vaccines market is estimated to be valued at US$ 966.6 Mn in 2019 and is expected to increase to US$ 1,418.2 Mn by 2027, exhibiting a CAGR of 4.9% over the forecast period (2019-2027)

Figure 1. Global Inactivated Polio and Rabies Vaccines Market Share (%), By Product Type (2019 & 2027)

Inactivated Polio and Rabies Vaccines  | Coherent Market Insights

(Source: Coherent Market Insights, 2020)

Increasing U.S. Food and Drug Administration (U.S. FDA) approvals for inactivated vaccines and their launches (IPV and IRV) for public use are expected to drive the global inactivated polio and rabies vaccines market growth over the forecast period.

Manufacturers are indulged in research, launches, and approvals of inactivated vaccines in the global inactivated polio and rabies vaccines market. For instance, in June 2019, AJ Vaccines introduced adjuvant IPV vaccine in Denmark. It is different from already available IPV vaccines, as it provides enhanced immunization to the infants and children from polio due to the presence of adjuvant and lower doses of vaccine that is required for immunization. Moreover, some new vaccines against rabies received U.S. Food and Drug Administration (U.S. FDA) approvals. For instance, in October 2019, Sanofi Pasteur SA announced to receive the U.S. FDA approval of Imovax, and in 2018, GlaxoSmithKline Biologicals, announced to receive the U.S. FDA approval for RabAvert. Both the vaccines can be used for pre-exposure immunization and post-exposure treatment of rabies.

Increasing incidences of rabies in the population is expected to spur the global inactivated polio and rabies vaccines market growth over the forecast period.

According to Center for Disease Control and Prevention, (CDC), 2019, in U.S., it has been reported that, other than dog, other animals are also responsible for spreading rabies in humans. For instance, according to the same source, in the U.S., during 2008-2017, 23 people were reported to be suffering from rabies, of which, eight people contracted rabies outside the U.S. The source of the rabies was checked and found that dog, bat, raccoon, and fox were found to be the carriers of rabies and rabies causes around 59,000 deaths world-wide every year. Despite of the availability of vaccine over 100 years, dog rabies have found to be common in the all regions with inadequate public health resources and having limited access to preventive treatment. Such regions also have few diagnostic facilities for life threatening diseases and surveillance of rabies occurrence among the animals is almost zero.

Increasing awareness about polio among the population is expected to drive the global inactivated polio and rabies vaccines market growth over the forecast period.

According to WHO, 2018, world-wide incidences of polio have been decreased by 99%, since 1988 and only 22 cases of children suffering from polio were found in 2017. Moreover, only three countries such as Pakistan, Afghanistan, and Nigeria were not successful in eradicating polio from their countries. According to the same source, it has also been estimated that failure to eradicate polio, over the span of ten years, can result in 200,000 polio patients globally. Furthermore, active participation of government for increasing awareness among the population through social media platforms, newspapers, and announcements is expected to reduce number of polio cases world-wide.  

Global Inactivated Vaccines Market - Regional Analysis

Regional segmentation of the global inactivated polio and rabies vaccines market comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

North America is expected to hold dominant position in the global inactivated polio and rabies vaccine market over the forecast period, owing to the increasing expenditure for maintaining rabies and polio free conditions in the region. Moreover, high income regions such as North America, Europe, and Latin America have eliminated cases of patients suffering from rabies and polio from their regions by increasing awareness among the population and conducting vaccination drives against rabies and polio, all over the region. High income regions incur very high expenditure, in order to maintain rabies and polio free environment and to survey any occurrence of the disease in the regions.

Moreover, according to the World Health Organization (WHO), 2019, low income regions such as Asia Pacific, Africa, and Latin America have reported highest number of deaths in the population because of rabies. For instance, according to the same source, per year around, 35,172 human deaths and 21,476 human deaths occur due to rabies in Asia Pacific and Africa respectively. The cases of patients suffering from polio in Asia Pacific are decreasing due to increasing awareness about the prevention of polio and rabies among the population and free immunization camps, which are organized by the government for immunizing the population against polio and rabies. Therefore, Asia Pacific is also expected to spur the global inactivated polio and rabies vaccines market growth over the forecast period.

Figure 2:  Global Inactivated Polio and Rabies Vaccines Market Share (%) Analysis, By Regions (2019-2027)

Inactivated Polio and Rabies Vaccines  | Coherent Market Insights

(Source: Coherent Market Insights, 2020)

Global Inactivated Polio and Rabies Vaccines Market - Restraints

The most important factor that can restrain the global inactivated vaccines market growth include safety of the vaccines. For instance, the inactivation process of the viruses may remain incomplete and the active virus may spread among the population causing the disease. Moreover, unavailability of the vaccines is another factor that is expected to hamper growth of the global inactivated vaccines market. For instance, in India, the polio drive, which was scheduled on 3rd February 2019, was postponed till 10th March 2019, due to unavailability of the polio vaccine.

Key Players

Some of the key players operating in the global inactivated vaccines market include Bharat Biotech., BIO-MED, Serum Institute of India Pvt. Ltd., Kedrion Biopharma Inc. GlaxoSmithKline plc. Bilthoven Biologicals, Merck & Co., Inc., and Pfizer Inc.

The incidences of polio globally is decreasing over the time due to government of the countries for creating awareness about the immunization against polio and rabies, among the population and increasing immunization camps. For instance, according to the World Health Organization (WHO), 2019, North America, Europe, and some Latin America are conducting polio immunization drives and creating awareness among the population, hence this has contributed to the eradication of polio from the regions.

The incidences of rabies have been controlled in high income countries while in low income countries the government is trying to increase the immunization in stray dogs as well as providing funding to the manufacturers to manufacture anti-rabies vaccines, in order to overcome the shortage of vaccines. For instance, several people of Asia Pacific and the African regions are reported to die due to rabies, therefore, government in these regions are conducting immunization drives, in which number of stray dogs are immunized against rabies. 

Market Dynamics

Polio vaccines are of two types such as oral polio vaccine (OPV) and inactivated polio vaccine (IPV). OPV consist of live and weakened polio virus, which are more active than the IPV. The only disadvantage of OPV is the release of the live virus through the waste of the humans, which can spread to the non-immunized humans. Hence, government is taking an initiative of eliminating usage of OPV and increase the use of IPV gradually. Moreover, developed countries such as the U.S. have already stopped recommending oral polio vaccine since 2000. Many research and development is being carried out for the production of new IPV vaccine, which exhibits enhanced immune response against the disease as compared to the currently available IPV.

Manufacturers are indulged in the research and development of more efficient inactivated polio vaccine by addition of adjuvant to the vaccine. For instance, Fractional - dose Inactivated Polio Vaccine (fIPV) with adjuvant for increased stimulation of the immune response as compared to IPV alone. Moreover, according to the clinical trials that are conducted by the University of Vermont (sponsor) (Start date – 2019, estimated completion date – 2020, currently the trial is in phase I), fIPV along with the adjuvant, dmLT, is being tested on healthy human population in order to check the immune response in the presence and absence of the adjuvant.

Moreover, Sanofi Pasteur SA offers, IPOL, an IPV, which is prepared with a combination of three types of poliovirus such as Type 1 (Mahoney), Type 2 (MEF-1), and Type 3 (Saukett), which provides immunity against the three types of polio viruses, to the children (as young as 6 weeks of age) and in adults.

Government from different regions are taking initiative for the prevention of the spread of rabies in humans by immunizing animals. For instance, in 2019, Texas completed 25 years of dropping packets of rabies vaccine over wild-life areas and prevent the spread of the deadly virus in humans. Moreover, according to the Texas Department of State Health Services’ (DSHS) Oral Rabies Vaccination Program (ORVP) successfully distributed around 1 million vaccine doses on January 22, 2019. The program was initiated in 1995. Usually, rabies spread to humans through saliva of infected animals especially, dogs, bats and raccoon.

Key features of the study:

  • This report provides in-depth analysis of the global inactivated polio and rabies vaccines market and provides market size (US$ XX Million) and Cumulative Annual Growth Rate (CAGR (XX %)) for the forecast period: 2019- 2027, considering 2018 as the base year.
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global inactivated polio and rabies vaccines market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies and future plans
  • Key companies covered as a part of this study include Bharat Biotech., BIO-MED, Serum Institute of India Pvt. Ltd., Kedrion Biopharma Inc. GlaxoSmithKline plc., Bilthoven Biologicals, Merck & Co., Inc., and Pfizer Inc.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to future product launches, end user upgrades, market expansion, and marketing tactics
  • The global inactivated polio and rabies vaccines market  report caters to various stakeholders in this industry, including investors, device/system manufacturers, distributors and suppliers for anesthesia and respiratory devices, research and consulting firms, new entrants, and financial analysts
  • Various strategy matrices used in analyzing the inactivated polio and rabies vaccines market would provide stakeholders vital inputs to make strategic decisions accordingly

Detailed Segmentation

Global Inactivated Polio and Rabies Vaccine Market, By Vaccine:

  • Inactivated Polio Vaccines
  • Inactivated Rabies Vaccines

Global Inactivated Polio and Rabies Vaccine Market, By Method of Inactivation:

  • Solvent Detergent Method
  • Radiation Method
  • pH Concentration
  • Heat Inactivation
  • Others

Global Inactivated Polio and Rabies Vaccine Market, By Age Group:

  • Pediatrics
  • Adults

Global Inactivated Polio and Rabies Vaccine Market, By Distribution Channel:

  • Government
  • Private

Global Inactivated Polio and Rabies Vaccine Market, By Region:

  • North America
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • S.
      • Canada
  • Latin America
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • Brazil
      • Mexico
      • Argentina
      • Rest of Latin America
  • Europe
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • K.
      • Germany
      • Italy
      • France
      • Spain
      • Russia
      • Rest of Europe
  • Asia Pacific
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
  • Middle East
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • GCC
      • Israel
      • Rest of Middle East
  • Africa
    • By Vaccine Type:
      • Inactivated Polio Vaccines
      • Inactivated Rabies Vaccines
    • By Method of Inactivation:
      • Solvent Detergent Method
      • Radiation Method
      • pH Concentration
      • Heat Inactivation
      • Others
    • By Age Group:
      • Pediatrics
      • Adults
    • By Distribution Channel:
      • Government
      • Private
    • By Country:
      • Central Africa
      • South Africa
      • North Africa
  • Company Profiles
    • Bharat Biotech
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Developments/Updates
      • Strategies
    • BIO-MED
    • Serum Institute of India Pvt. Ltd.
    • Kedrion Biopharma Inc.
    • GlaxoSmithKline plc.
    • Bilthoven Biologicals
    • Merck & Co., Inc.
    • Pfizer Inc.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Vaccine
      • Market Snippet, By Method of Inactivation
      • Market Snippet, By Age Group
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Industry Trend
    • Mergers and Acquisitions
    • Technology Overview
    • Promotion Initiatives
  4. Global Inactivated Polio and Rabies Vaccines Market, By Vaccine, 2019 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Inactivated Polio Vaccine
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Inactivated Rabies Vaccine
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  5. Global Inactivated Polio and Rabies Vaccines Market, By Method of Inactivation, 2019 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Solvent Detergent Method
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Radiation Method
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • pH Concentration
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Heat Inactivation
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Others
      1. Introduction
      2. Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  6. Global Inactivated Polio and Rabies Vaccines Market, By Age Group, 2019 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Pediatrics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Adults
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  7. Global Inactivated Polio and Rabies Vaccines Market, By Distribution Channel, 2019 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Government
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Private
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  8. Global Inactivated Polio and Rabies Market, By Region, 2019 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
    • North America
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of Inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027 (US$ Mn)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027 (US$ Mn)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027 (US$ Mn)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Vaccine, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Method of inactivation, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Age Group, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2016 – 2027 (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  9. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Bharat Biotech
        • Company Overview
        • Product  Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • BIO-MED
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Serum Institute of India Pvt. Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Kedrion Biopharma Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • GlaxoSmithKline plc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Bilthoven Biologicals
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Merck & Co., Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Pfizer Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
    • Analyst Views
  10. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 46 market data tables and 27 figures on "Inactivated Polio and Rabies Vaccines Market - Global forecast to 2027”.

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