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  • Published In : Apr 2023
  • Code : CMI5650
  • Pages :171
  • Formats :
      Excel and PDF
  • Industry : Pharmaceutical

The global intramuscular vaccine adjuvants market size was valued at $650.6 million in 2022 and is expected to reach $1,088.9 million by 2030, with a CAGR of 6.7% during the forecast period. The increasing prevalence of infectious diseases, coupled with the growing need for effective vaccines, is one of the key factors driving the growth of this market.

Intramuscular vaccine adjuvants are substances that are added to vaccines to enhance their effectiveness. They stimulate the immune system, enabling it to produce a stronger and more effective response to the vaccine. The intramuscular vaccine adjuvants market has been growing steadily in recent years, and is expected to continue its growth trajectory in the coming years.

Intramuscular Vaccine Adjuvants Market Regional Insights:

North America held the largest share of the intramuscular vaccine adjuvants market in 2020, and is expected to maintain its dominance during the forecast period. This can be attributed to the high prevalence of infectious diseases in the region, along with the presence of key market players. Additionally, the increasing adoption of advanced technologies for vaccine development is expected to further fuel market growth in North America.

Europe is expected to be a significant contributor to the growth of the intramuscular vaccine adjuvants market during the forecast period. This is due to the presence of a well-established healthcare infrastructure, coupled with the increasing demand for effective vaccines. Moreover, the rising incidence of chronic diseases and infectious diseases in the region is expected to further boost the demand for intramuscular vaccine adjuvants.

The Asia-Pacific region is projected to witness the highest growth rate during the forecast period, owing to the increasing investments in vaccine development by both public and private organizations. Additionally, the rising prevalence of infectious diseases and the increasing awareness about the benefits of vaccination are expected to further drive market growth in this region. The large population base in countries like China and India also presents a significant growth opportunity for the intramuscular vaccine adjuvants market in the region.

Global Intramuscular Vaccine Adjuvants Market Drivers:

  1. Increasing Prevalence of Infectious Diseases: One of the major drivers of the intramuscular vaccine adjuvants market is the increasing prevalence of infectious diseases. Diseases such as influenza, hepatitis, and human papillomavirus (HPV) continue to be a significant public health burden. The use of intramuscular vaccine adjuvants helps in improving the efficacy of vaccines, which is particularly important for immunocompromised individuals who may have a weaker immune response to vaccines.
  2. Growing Need for Effective Vaccines: There is a growing need for effective vaccines that can provide long-lasting protection against infectious diseases. Intramuscular vaccine adjuvants play a crucial role in improving vaccine efficacy by enhancing the immune response to vaccines. This is particularly important in the case of elderly individuals and those with weakened immune systems, who may not mount a robust immune response to traditional vaccines.
  3. Technological Advancements in Vaccine Development: Advancements in vaccine development technologies have led to the development of more effective vaccines. Intramuscular vaccine adjuvants have been instrumental in improving the efficacy of these vaccines. The use of advanced technologies such as recombinant DNA technology, adeno-associated virus (AAV) vectors, and mRNA-based vaccines is expected to further drive the growth of the intramuscular vaccine adjuvants market.
  4. Government Initiatives to Promote Vaccination: Governments across the world are taking initiatives to promote vaccination and reduce the burden of infectious diseases. For instance, the Centers for Disease Control and Prevention (CDC) in the United States recommends annual influenza vaccination for everyone over the age of six months. This has led to an increased demand for intramuscular vaccine adjuvants, which are used to improve the efficacy of influenza vaccines.

Intramuscular Vaccine Adjuvants Market  Report Coverage

Report Coverage Details
Base Year: 2022 Market Size in 2022: US$ 650.6 Mn
Historical Data for: 2017 to 2021 Forecast Period: 2023 - 2030
Forecast Period 2023 to 2030 CAGR: 6.7% 2030 Value Projection: US$ 1,088.9 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East & Africa
Segments covered:
  • By Type of Adjuvants: Oil-based Adjuvants, Liposome-based Adjuvants, Polymer-based Adjuvants, Mineral-based Adjuvants, Others
  • By End-users: Pediatrics, Adults, Geriatrics
  • By Applications: Infectious Diseases, Cancer, Others
  • By Distribution Channels: Hospitals, Clinics, Research Centers
Companies covered:

Novavax, Inc., Adjuvance Technologies, Inc., Invivogen, Vaxine Pty Ltd., SEPPIC, SPI Pharma, Inc., Agenus Inc., Avanti Polar Lipids, Inc., CSL Limited, OZ Biosciences

Growth Drivers:
  • Increasing Prevalence of Infectious Diseases
  • Growing Need for Effective Vaccines
  • Technological Advancements in Vaccine Development
  • Government Initiatives to Promote Vaccination
Restraints & Challenges:
  • Regulatory challenges
  • High development costs
  • Public perception and vaccine hesitancy

Global Intramuscular Vaccine Adjuvants Market Opportunities:

  1. Increasing demand for vaccines due to the growing prevalence of infectious diseases: With the COVID-19 pandemic, there has been a surge in demand for vaccines, including intramuscular ones. This trend is likely to continue in the future, creating opportunities for the intramuscular vaccine adjuvants market.
  2. Development of new and more effective adjuvants: As researchers learn more about the immune system and how vaccines work, they can develop adjuvants that are better suited for specific vaccines and populations. This can lead to improved vaccine efficacy and safety, as well as expanded markets for adjuvants.
  3. Growing focus on personalized medicine and precision vaccines: This is expected to create new opportunities for intramuscular vaccine adjuvants. By tailoring vaccines to individual patients or populations, adjuvants can be used to enhance the immune response in a more targeted way, leading to better outcomes.

Global Intramuscular Vaccine Adjuvants Market Trends:

  1. Increasing demand for vaccines: With the ongoing COVID-19 pandemic and the growing prevalence of infectious diseases worldwide, there is a significant increase in demand for vaccines. This has led to a surge in the production and distribution of intramuscular vaccines, which require adjuvants to enhance their effectiveness.
  2. Emergence of new infectious diseases: In addition to COVID-19, new infectious diseases continue to emerge, creating a need for new vaccines and adjuvants. For example, the recent outbreak of Ebola virus in Africa highlighted the need for new vaccines and adjuvants to combat the disease.
  3. Increasing research and development: With the growing demand for vaccines and adjuvants, there is increased research and development in this field. Researchers are exploring new adjuvant technologies and formulations to enhance the effectiveness and safety of vaccines.
  4. Expansion of the biopharmaceutical industry: The biopharmaceutical industry, which includes vaccine development and production, is expanding rapidly. This growth is driven by the increasing demand for vaccines and the emergence of new technologies and adjuvants.

Global Intramuscular Vaccine Adjuvants Market Restraints:

  1. Regulatory challenges: The approval process for new adjuvants can be time-consuming and expensive. The regulatory agencies require a rigorous evaluation of safety and efficacy, which can slow down the development and commercialization of new adjuvants.
  2. High development costs: Developing new adjuvants can be expensive due to the need for extensive research and clinical trials. The costs of manufacturing and quality control can also be high, which can limit the number of companies that can afford to develop and commercialize adjuvants.
  3. Public perception and vaccine hesitancy: Some members of the public may be hesitant to receive vaccines that contain adjuvants, which can affect the demand for those vaccines. This can be due to concerns about the safety and efficacy of adjuvants, as well as a general mistrust of vaccines.

Global Intramuscular Vaccine Adjuvants Market Recent Developments:

New product launches

  1. MF59: MF59 is an adjuvant used in influenza vaccines, which was first approved by the FDA in 1997. In recent years, new formulations of MF59 have been developed, such as MF59C.1, which has been used in the Novartis Fluad vaccine for older adults.
  2. AS03: AS03 is an adjuvant used in the H1N1 pandemic vaccine, which was approved by the FDA in 2009. AS03 has also been used in the GlaxoSmithKline Shingrix vaccine for shingles, which was approved in 2017.
  3. CpG 1018: CpG 1018 is a synthetic adjuvant used in the Pfizer-BioNTech and Moderna COVID-19 vaccines. It has been shown to enhance the immune response and increase vaccine efficacy.
  4. Advax: Advax is an adjuvant developed by Vaxine Pty Ltd, which has been shown to enhance the immune response in preclinical studies. Advax is being developed for use in vaccines for infectious diseases and cancer.
  5. Matrix-M: Matrix-M is an adjuvant developed by Novavax, which has been shown to enhance the immune response and increase vaccine efficacy. Matrix-M has been used in the Novavax COVID-19 vaccine, which is currently being evaluated by regulatory agencies for approval.

Acquisition and partnerships

  1. In 2021, Croda International acquired Brenntag Biosector, a global leader in adjuvant technologies, to expand their portfolio of adjuvant products and improve their market position.
  2. In 2020, Vaxine Pty Ltd entered into a partnership with Medytox Inc. to develop a COVID-19 vaccine using Vaxine's adjuvant technology.

Global Intramuscular Vaccine Adjuvants Market Top 10 Key Player

  1. Novavax, Inc.
  2. Adjuvance Technologies, Inc.
  3. Invivogen
  4. Vaxine Pty Ltd.
  5. SEPPIC
  6. SPI Pharma, Inc.
  7. Agenus Inc.
  8. Avanti Polar Lipids, Inc.
  9. CSL Limited
  10. OZ Biosciences.

Frequently Asked Questions

The global intramuscular vaccine adjuvants market size was valued at $650.6 million in 2022 and is expected to reach $1,088.9 million by 2030

 Increasing prevalence of infectious diseases is expected to drive the market.

The North America region will lead the in market.

The market growing at a CAGR of 6.7% during the forecast period.

Major players operating in the market include Novavax, Inc., Adjuvance Technologies, Inc., Invivogen, Vaxine Pty Ltd., SEPPIC, SPI Pharma, Inc., Agenus Inc., Avanti Polar Lipids, Inc., CSL Limited, OZ Biosciences

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