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Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

The global orthobiologics market is predominantly driven by the global rise in geriatric population and lifestyle changes coupled with growing awareness of sports and outdoor activities among the older as well as younger generation.

Statistics:

The global orthobiologics market is estimated to account for US$ 8,708.4 Mn in terms of value by the end of 2027.

Global Orthobiologics Market: Drivers

High prevalence of chronic arthritis is expected to propel growth of the global orthobiologics market over the forecast period. For instance, according to the Centers for Disease Control and Prevention (CDC)’s May 2019 report, an estimated 54.4 million US adults have diagnosed arthritis, which accounted for around 1 in 4 people in the U.S. 

Moreover, increasing geriatric population is also expected to aid in growth of the market. For instance, according to the U.S. Census Bureau, the U.S. geriatric population is expected to reach 77 million by 2034.     

Statistics:

North America held dominant position in the global orthobiologics market in 2019, accounting for 45.4% share in terms of volume, followed by Europe and Asia Pacific, respectively.

Figure 1: Global Orthobiologics Market Share (%) Value, By Region, 2019

Orthobiologics  | Coherent Market Insights

Global Orthobiologics Market: Restraints

Lack of reimbursement is expected to hinder growth of the global orthobiologics market. The Medicare cuts have affected the orthopedic reimbursements according to American Association of Orthopedic Surgeons.

Moreover, stringent regulatory requirements are also expected to limit the growth of the market.

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Orthobiologics Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2019: US$ 5,519.9 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 5.9% 2027 Value Projection: US$ 8,708.4 Mn
Geographies covered:
  • North America: U.S., Canada
  • Latin America: Brazil, Argentina, Mexico, Rest of Latin America
  • Europe: Germany, U.K., France, Spain, Italy, Russia, Rest of Europe
  • Asia Pacific: China, Japan, India, Australia, South Korea, ASEAN, Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, Rest of Middle East
  • Africa: North Africa, Central Africa, South Africa
Segments covered:
  • By Product Type: Bone Allograft, Machined Bones, Demineralized Bone Matrix, Synthetic Bone Substitutes, BMP, Stem Cell Therapy, Viscosupplementation.
  • By Application: Spinal Fusion, Trauma, Reconstructive Surgeries.
Companies covered:

Zimmer Biomet Holdings, Inc., Bone Biologics Corp, Harvest Technologies Corporation, Globus Medical, Inc., Smith & Nephew plc, Stryker Corporation, Genzyme, Alphatec Spine, Inc., Bacterin International, Inc., DePuy Synthes, Inc. (A Johnson & Johnson Company), Exactech, Inc., Globus Medical, Inc., Integra LifeSciences Corporation, Medtronic, Plc, NuVasive, Inc., Orthofix Holdings, Inc., SeaSpine Holdings Corporation, and Ortho Regenerative Technologies Inc..

Growth Drivers:
  • Increasing prevalence of chronic artheritis
  • Approval and launch of new products
Restraints & Challenges:
  • Lack of reimbursement

Global Orthobiologics Market: Opportunities  

Rise in cell based matrices is expected to offer lucrative growth opportunities for players in the global orthobiologics market. Growing interest in the use of biologic agents such as platelet rich plasma and stem cell therapy is expected to have significant potential in the years of forecast. Tissue engineered bones have the potential to alleviate the demand arising from shortage of allografts for aiding the bone healing process.

Moreover, increasing adoption of platelet rich plasma, autologous conditioned serum, bone marrow aspirate concentrate, and adipose derived stromal cell therapy is also expected to aid in growth of the market.

Statistics:

The global orthobiologics market was valued at US$ 5,519.9 Mn in 2019 and is forecast to reach a value of US$ 8,708.4 Mn by 2027 at a CAGR of 5.9% between 2020 and 2027.

Figure 2: Global Orthobiologics Market Value (US$ Bn), 2016 – 2027

Orthobiologics  | Coherent Market Insights

Market Trends/Key Takeaways

High prevalence of sports-related injuries is expected to propel growth of the global orthobiologics market. For instance, in November 2018, the study, ‘Results on sports-related injuries in children from NHS emergency care dataset Oxfordshire pilot: an ecological study’, children aged between 0–19 years accounted for 47.4% of sports injury-related emergency department attendances and around 23.5% of sports injury-related admissions for all ages.

The global orthobiologics market is witnessing fluctuations in the cost of orthobiologics. For instance, a University of Alabama at Birmingham study, published in Sports Health, in October 2019, reported significant cost variability ranging from a few hundred dollars to as much as US$ 12,000 in orthobiologics therapies.

Global Orthobiologics Market: Competitive Landscape

Major players operating in the global orthobiologics market include, Zimmer Biomet Holdings, Inc., Bone Biologics Corp, Harvest Technologies Corporation, Globus Medical, Inc., Smith & Nephew plc, Stryker Corporation, Genzyme, Alphatec Spine, Inc., Bacterin International, Inc., DePuy Synthes, Inc. (A Johnson & Johnson Company), Exactech, Inc., Globus Medical, Inc., Integra LifeSciences Corporation, Medtronic, Plc, NuVasive, Inc., Orthofix Holdings, Inc., SeaSpine Holdings Corporation, and Ortho Regenerative Technologies Inc.

Global Orthobiologics Market: Key Developments

Major players in the global orthobiologics market are focused on approval and launch of new products to expand their product portfolio. For instance, in August 2020, Ortho Regenerative Technologies Inc. announced that Ortho-R, a Chitosan-based matrix biopolymer mixed with platelet rich plasma, is designated as a Drug/Biologic combination product, by the FDA Office for Combination Products.

Similarly, in June 2020, SeaSpine Holdings Corporation announced the full commercial launches of Mariner MIS and Mariner Outrigger, the systems used to enhance surgical flow in revision of previous fusions.

Orthobiologics are substances used to heal injuries such as fractures and injured muscles, ligaments, and tendons within a short period of time. Orthobiologics are made from substances that naturally occur in the body. Some examples of orthobiologics are bone grafts, autologous blood, autologous conditioned serum, platelet rich plasma, growth factors, and stem cells. Increasing prevalence of injury and facture due to falls and road accidents along with increasing prevalence of chronic arthritis are expected to augment growth of the orthobiologics market

Key features of the study:

  • This report provides in-depth analysis of the Global Orthobiologics market  and provides market size (US$ million) and compound annual growth rate (CAGR %) for the forecast period (2020–2027), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategy adopted by key players
  • It profiles key players in the Global Orthobiologics market  based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include, Zimmer Biomet Holdings, Inc., Bone Biologics Corp, Harvest Technologies Corporation, Globus Medical, Inc., Smith & Nephew plc, Stryker Corporation, Genzyme, Alphatec Spine, Inc., Bacterin International, Inc., DePuy Synthes, Inc. (A Johnson & Johnson Company), Exactech, Inc., Globus Medical, Inc., Integra LifeSciences Corporation, Medtronic, Plc, NuVasive, Inc., Orthofix Holdings, Inc., SeaSpine Holdings Corporation, and Ortho Regenerative Technologies Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, technology up-gradation, market expansion, and marketing tactics
  • The Global Orthobiologics market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the Global Orthobiologics market

Detailed Segmentation:

  • Global Orthobiologics Market, By Product Type:
    • Bone Allograft
    • Machined Bones
    • Demineralized Bone Matrix
    • Synthetic Bone Substitutes
    • BMP
    • Stem Cell Therapy
    • Viscosupplementation
  • Global Orthobiologics Market, By Application:
    • Spinal Fusion
    • Trauma
    • Reconstructive Surgeries
  • Global Orthobiologics Market, By Region:
    • North America
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • U.K.
        • Germany
        • France
        • Spain
        • Italy
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • China
        • Japan
        • India
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • GCC Countries
        • Israel
        • Rest of Middle East
    • Africa
      • By Product Type:
        • Bone Allograft
        • Machined Bones
        • Demineralized Bone Matrix
        • Synthetic Bone Substitutes
        • BMP
        • Stem Cell Therapy
        • Viscosupplementation
      • By Application
        • Spinal Fusion
        • Trauma
        • Reconstructive Surgeries
      • By Country
        • North Africa
        • Central Africa
        • South Africa
  • Company Profiles
    • Zimmer Biomet Holdings, Inc. *
      • Company Overview
      • Product Portfolio
      • Key Highlights
      • Financial Overview
      • Strategies
    • Bone Biologics Corp
    • Harvest Technologies Corporation
    • Globus Medical, Inc.
    • Smith & Nephew plc
    • Stryker Corporation
    • Genzyme
    • Alphatec Spine, Inc.
    • Bacterin International, Inc.
    • DePuy Synthes, Inc. (A Johnson & Johnson Company)
    • Exactech, Inc.
    • Globus Medical, Inc.
    • Integra LifeSciences Corporation
    • Medtronic, Plc
    • NuVasive, Inc.
    • Orthofix Holdings Inc.
    • SeaSpine Holdings Corporation
    • Ortho Regenerative Technologies Inc.
  •  “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By Country
      • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Key Highlights
    • Product launch
    • PEST Analysis
    • Technological Advancements
    • Regulatory Scenario
    • Mergers and Acquisitions
  4. Global Orthobiologics Market, By Product Type, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Bone Allograft
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Machined Bones
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Demineralized Bone Matrix
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Synthetic Bone Substitutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • BMP
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Stem Cell Therapy
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Viscosupplementation
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  5. Global Orthobiologics Market, By Application, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Spinal Fusion
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Trauma
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Reconstructive Surgeries
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  6. Global Orthobiologics Market, By Region, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017–2026
    • North America
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • Germany
        • U.K.
        • France
        • Spain
        • Italy
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • China
        • Japan
        • India
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • GCC Countries
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Product Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Application, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  7. Competitive Landscape
    • Company Profiles
      • Zimmer Biomet Holdings, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Bone Biologics Corp
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Harvest Technologies Corporation
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Globus Medical, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Smith & Nephew plc
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Stryker Corporation
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Genzyme
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Alphatec Spine, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Bacterin International, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • DePuy Synthes, Inc. (A Johnson & Johnson Company)
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Exactech, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Globus Medical, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Integra LifeSciences Corporation
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Medtronic, Plc
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • NuVasive, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Orthofix Holdings Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • SeaSpine Holdings Corporation
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Ortho Regenerative Technologies Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
  8. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 22 market data tables and 14 figures on “Orthobiologics Market - Global forecast to 2027”.

Frequently Asked Questions

The Global Orthobiologics market size was valued at US$ 5,519.9 million in 2019 and is estimated to exhibit a CAGR of 5.9% between 2020 and 2027.
Viscosupplementation segment held the major market share in 2019 owing to an increasing prevalence of chronic arthritis
Major factor driving the growth of Global Orthobiologics market during the forecast period increasing prevalence of chronic arthritis, increasing research & development , and adoption of expansion strategies from major companies.
Major factors hampering the growth of the Global Orthobiologics market during the forecast period constitutes of contamination of lack of reimbursement.
North America market is expected to generate the highest revenue during the forecast period.
Some of the key players operating in the market are Zimmer Biomet Holdings, Inc., Bone Biologics Corp, Harvest Technologies Corporation, Globus Medical, Inc., Smith & Nephew plc, Stryker Corporation, Genzyme, Alphatec Spine, Inc., Bacterin International, Inc., DePuy Synthes, Inc. (A Johnson & Johnson Company), Exactech, Inc., Globus Medical, Inc., Integra LifeSciences Corporation, Medtronic, Plc, NuVasive, Inc., Orthofix Holdings, Inc., SeaSpine Holdings Corporation, and Ortho Regenerative Technologies Inc..
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