The renal denervation devices market is estimated to be valued at USD 1,253.4 Mn in 2025 and is expected to reach USD 2,332.1 Mn by 2032, exhibiting a compound annual growth rate (CAGR) of 14.7% from 2025 to 2032.
The global renal denervation devices market is expected to grow at a rapid rate owing to the increasing prevalence of hypertension among the population and increasing inorganic strategies among industry players will aid in the market growth over the forecast period. The increasing focus on radiofrequency-based renal denervation technologies is having a significant impact on the global renal denervation devices market. Traditionally, renal denervation treatments have relied on ultrasound-based techniques to disrupt renal nerves through either ablation or damage.
However, the high procedural costs associated with renal denervation devices and the procedure is a major factor restraining the growth of the global renal denervation devices market.
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The increasing prevalence of hypertension and its associated cardiovascular complications is profoundly accelerating the demand for innovative treatment modalities such as renal denervation (RDN) devices. The technology aligns with current trends toward targeted, device-based interventions, offering a viable alternative or adjunct to pharmacotherapy, particularly for patient’s refractory to standard treatments.
For instance, according to a study by the World Heart Report, in May 2025, modest weight loss of 5–10% can significantly improve cardiovascular risk factors like high blood pressure, abnormal cholesterol levels, and insulin resistance, while greater weight loss offers even greater benefits, such as lowering the risk of heart attacks and strokes.
In terms of procedure type, percutaneous renal denervation is expected to contribute 36.4% share of the market due to its potential to provide an effective alternative for patients who do not respond well to medication alone.
Percutaneous renal denervation is a minimally invasive procedure designed to treat resistant hypertension by disrupting the nerves in the renal arteries that contribute to high blood pressure. This technique involves threading a catheter through the blood vessels to the renal arteries and delivering controlled energy, such as radiofrequency or ultrasound, to reduce nerve activity.
Artificial Intelligence (AI) is rapidly transforming the healthcare landscape, and the renal denervation (RDN) devices market is no exception. This sector, focused on treating resistant hypertension through targeted nerve ablation in the renal arteries, is witnessing significant advancements fueled by AI integration.
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North America accounted for the largest market share of over 55% in 2025 and is projected to remain dominant over the forecast period. The high prevalence of hypertension and the presence of key market players are the key factors driving the growth of the market in this region.
For instance, according to a report by the Centers for Disease Control and Prevention (CDC) in October 2024, approximately 919,032 people died from cardiovascular disease in the United States. That is equivalent to one in every three deaths.
Asia Pacific is the fastest-growing market for renal denervation devices owing to the increasing geriatric population and the rising number of chronic diseases among the population. These factors will aid in the market growth over the forecast period.
For instance, according to a study by the National Institutes of Health in July 2024, between 2025 and 2050, crude cardiovascular mortality is expected to increase by 91.2% despite a 23.0% decrease in the age-standardized cardiovascular mortality rate.
The U.S. is a leader in the renal denervation devices market due to its highly advanced healthcare system and strong emphasis on cardiovascular disease treatment. Hospitals and clinics widely adopt innovative medical technologies, and there is significant investment in clinical research related to hypertension therapies.
According to a study by the National Institutes of Health in January 2025, almost half of adults (45%) with uncontrolled high blood pressure have a blood pressure of 140/90 mmHg or higher. This includes 37 million U.S. adults.
Germany is a prominent market in Europe, known for its cutting-edge medical technology and extensive healthcare infrastructure. The country has a high prevalence of cardiovascular diseases, which creates demand for effective treatment options like renal denervation. German hospitals focus on minimally invasive procedures, supported by comprehensive healthcare insurance coverage that makes these treatments accessible to many patients.
As per a study by the World Heart Federation, the total mortality from cardiovascular disease (CVD) accounts for a percentage of all deaths. Specifically, premature mortality due to cardiovascular disease (CVD)—defined as deaths occurring between the ages of 30 and 70—accounts for 35.06% of deaths in males and 40.74% in females.
China is emerging as a major player in the renal denervation devices field due to its large population and increasing cases of resistant hypertension. The healthcare system is rapidly expanding with improved access to advanced medical technologies, especially in urban centers. Growing awareness of kidney and cardiovascular health drives demand for novel treatments, and government initiatives aim to improve chronic disease management nationwide.
The 2023 report on Cardiovascular Health and Diseases in China reveals that there are currently 330 million individuals living with cardiovascular disease in the country.
India’s growing healthcare infrastructure and rising burden of hypertension make it an important market for renal denervation devices. Although adoption is still in early stages, major cities are seeing increased use of innovative therapies for difficult-to-treat hypertension cases. Improved training of healthcare providers and greater patient awareness contribute to the expanding interest in minimally invasive procedures to reduce cardiovascular risks.
According to the American Heart Association Journal, ischemic heart disease and stroke are the leading causes of cardiovascular disease (CVD) deaths, accounting for over 80% of cases. The Global Burden of Disease study estimates that India’s age-standardized CVD death rate is 272 per 100,000 population, which is higher than the global average of 235 per 100,000 population.
| Report Coverage | Details | ||
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| Base Year: | 2024 | Market Size in 2025: | USD 1,253.4 Mn |
| Historical Data for: | 2020 To 2024 | Forecast Period: | 2025 To 2032 |
| Forecast Period 2025 to 2032 CAGR: | 14.7% | 2032 Value Projection: | USD 2,332.1 Mn |
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| Companies covered: |
Medtronic, Recor Medical, Inc., Boston Scientific Corp, Kona Medical, Terumo Corporation, Abbott, Ablative Solutions, and Others |
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*Definition: Renal denervation devices are medical devices used in the treatment of resistant hypertension, a condition where a patient's high blood pressure is unresponsive to traditional therapies such as medications. Resistant hypertension is a serious health condition that increases the risk of heart attack, stroke, kidney disease, and other complications.
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Komal Dighe is a Management Consultant with over 8 years of experience in market research and consulting. She excels in managing and delivering high-quality insights and solutions in Health-tech Consulting reports. Her expertise encompasses conducting both primary and secondary research, effectively addressing client requirements, and excelling in market estimation and forecast. Her comprehensive approach ensures that clients receive thorough and accurate analyses, enabling them to make informed decisions and capitalize on market opportunities.
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