Surgical Glues Market Analysis & Forecast: 2025-2032

Surgical Glues Market Size and Forecast – 2025 – 2032

The Surgical Glues Market size is estimated to be valued at USD 1.9 billion in 2025 and is expected to reach USD 3.4 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 8.3% from 2025 to 2032.

Global Surgical Glues Market Overview

Surgical glues also known as surgical adhesives or sealants are used after a traumatic injury or surgery to fix internal or external tissue together. Surgical glues are excellent materials for wound closure as they use a chemical bond to hold tissue together for healing or to aid as a barrier to stop the flow of bodily fluids. They offer advantages over conventional approaches such as sutures and staples. The five main types of surgical glues are fibrin sealants, cyanoacrylates, glutaraldehyde glues, hydrogels, and collagen based compounds.

However, scientists in the U.S. have recently created a highly elastic surgical glue that can quickly seal even the toughest wounds in seconds without stitches or staples. The new glue known as MeTro seals the wound and sets in 60 seconds once treated with UV light. The glue composed from a special material contains a degrading enzyme that can last from hours to months and dissolves once the wound is healed. The new glue is said to be ideal for sealing complex wounds in tissues that would repeatedly expand and relax such as heart, lungs, and arteries.

Key Takeaways

• Cyanoacrylate-based surgical glues remain the dominating product segment, accounting for 45% of the market share in overall market revenue. Their high bonding strength and rapid polymerization make them preferred in emergency and cardiovascular surgeries.

• North America holds the largest market share at approximately 34%, supported by extensive healthcare infrastructure and strong presence of leading companies.

• Asia Pacific, with a CAGR exceeding 9%, is the fastest-growing region due to rising healthcare investments, government initiatives, and growing surgical volumes, especially in China and India.

Surgical Glues Market – Segmentation Analysis

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Surgical Glues Market Insights, By Product Type

Cyanoacrylate-Based surgical glues in product type segment boosts with 45% of market share due to their rapid bonding abilities and strong adhesion properties. They are extensively used in emergency surgeries and in wound closure where immediate sealing is essential. This sub segment’s dominance is supported by steady innovation that improves biocompatibility and reduces cytotoxicity. Fibrin-Based adhesives represent the fastest-growing sub segment driven by increasing applications in cardiovascular surgeries and their favorable safety profile that mimics natural clotting; recent clinical trials reported a 25% improved wound healing rate compared to synthetic options.

Surgical Glues Market Insights, By Application

Cardiovascular Surgery holds the highest application share in application segment due to the critical need for reliable vascular sealing and reduced operation times. Use of fibrin- and cyanoacrylate-based adhesives has expanded to procedures such as bypass grafting and valve repair. Orthopedic Surgery represents the fastest-growing application owing to the rise in fracture treatments and the development of surgical glues incorporated with bone-regenerative agents. This segment’s growth is accelerated by aging global demographics and sports injury prevalence.

Surgical Glues Market Insights, By End-User

Hospitals segment holds the majority of surgical glues in end user, as they perform the highest volume of procedures requiring tissue adhesives, especially in cardiovascular and orthopedic surgeries. This dominance is underpinned by advanced infrastructure and higher budgets enabling access to latest adhesive technologies. Ambulatory Surgical Centers are the fastest-growing segment due to the shift towards outpatient minimally invasive surgeries driven by cost efficiency and patient preference for quicker recovery. Specialty Clinics, particularly in dermatology and cosmetic surgery, show consistent demand growth for specialized adhesive formulations aimed at aesthetic outcomes.

Surgical Glues Market Trends

• The Surgical Glues market is witnessing a material shift towards bio-based and synthetic hybrid adhesives that blend the advantages of both categories to maximize biocompatibility and adhesive strength.

• Between 2023 and 2025, several companies introduced biohybrid formulations, with a 30% higher clinical adoption rate reported in Europe compared to prior generation adhesives.

• Additionally, digital wound closure technologies, including laser-activated glues, are gaining traction, particularly in cosmetic and ophthalmic surgeries.

• Emerging regulatory harmonization across Asia-Pacific is reducing entry barriers for innovative surgical glue formulations, accelerating market growth in the region.

• Increasing awareness regarding the environmental impact of surgical materials is also directing R&D efforts towards biodegradable and eco-friendly options.

Surgical Glues Market Insights, By Geography

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North America Surgical Glues Market Analysis and Trends

In North America holds the dominant industry share of approximately 34%, fueled by advanced healthcare infrastructure, a high rate of surgical procedures, and proactive regulatory support for innovative products. The presence of major market companies such as Medtronic and Johnson & Johnson significantly contributes to ongoing product development and commercial reach.

Asia Pacific Surgical Glues Market Analysis and Trends

Meanwhile, the Asia Pacific region exhibits the fastest growth, with a CAGR exceeding 9%, driven by increasing healthcare expenditure, government healthcare reforms promoting minimally invasive surgery, and a surge in elective procedures. India and China lead in surgical volume expansion, supported by local manufacturing initiatives and rising patient awareness.

Surgical Glues Market Outlook for Key Countries

United States Surgical Glues Market Analysis and Trends

The USA's surgical glues market is a major contributor to global revenue, accounting for nearly 28% of the total industry revenue in 2024. Key players such as Stryker Corporation and Baxter International have strategically launched innovative cyanoacrylate and fibrin-based glues tailored to cardiovascular and orthopedic surgeries. Government incentives for research in minimally invasive procedures have propelled adoption rates by 15% since 2023, while increasing surgical volumes due to an aging population sustain ongoing demand.

Germany Surgical Glues Market Analysis and Trends

Germany's market is prominent in the European region, with extensive utilization in cardiovascular and dermatology surgeries. The country accounts for roughly 12% of the regional market size due to strong clinical adoption and supportive reimbursement policies for bioadhesive products. Leading local companies focus on product innovation in biohybrid adhesives, which has resulted in a 10% increase in market share from 2023 to 2025. The German market also benefits from integration with EU-wide regulatory frameworks streamlining product approvals.

Analyst Opinion

• Enhanced Demand in Minimally Invasive Surgeries: The surge in minimally invasive procedures has driven a significant increase in the demand for surgical glues, particularly cyanoacrylate-based adhesives, which accounted for nearly 45% of the market share in 2024. Hospitals in North America reported a 12% rise in the adoption of surgical glues during laparoscopic surgeries compared to 2023, emphasizing their role in reducing operation time and post-surgical complications.

• Price Dynamics and Raw Material Supply: Fluctuations in the cost of raw materials like polymethyl methacrylate and fibrinogen have modestly influenced pricing strategies. For instance, in 2025, the average price for synthetic surgical adhesives increased by 4.5% due to supply chain disruptions in polymer production sectors in Asia. This has prompted manufacturers to optimize production capacity while maintaining competitive pricing.

• Varied Use Cases Across Treatment Areas: Cardiovascular and orthopedic surgeries have emerged as prominent end-user segments, representing more than 40% of the surgical glues market volume in 2024. The expansion is supported by applications such as vascular repair and fracture fixation. Hospitals across Europe observed a 15% increase in cardiovascular surgeries utilizing surgical adhesives in 2024, underscoring this trend.

Market Scope

Surgical Glues Market Growth factors

• The rising prevalence of chronic and lifestyle-related diseases has intensified the need for efficient surgical closure techniques, substantially fuelling market revenue.

• Technological advancements in biocompatible adhesives have enhanced the safety and outcomes of surgeries, increasing the adoption rate globally.

• In developing economies such as Brazil, government healthcare initiatives promoting minimally invasive surgeries contribute further to market expansion.

• Moreover, the increasing focus on reducing surgical site infections (SSI) by employing more effective adhesive products is amplifying penetration in hospital settings.

• The expansion of ambulatory surgical centers providing quick recovery solutions is also a notable contributor to market dynamics.

Surgical Glues Market Development

• In April 2025, Baxter International Inc., a global leader in advancing surgical innovation, launched Hemopatch Sealing Hemostat with room temperature storage. The product's development maximizes accessibility in the operating room, giving surgeons a quick fix to stop bleeding or stop leaks. You can now order the goods anywhere in Europe.

• In October 2024, Solventum introduced Double-Coated Medical Tape with Hi-Tack Silicone and Acrylate Adhesives on Liner (2487 Hi-Tack Silicone Tape), an advanced adhesive solution designed for sensitive skin that allows medical wearable manufacturers to expand the use of their devices to a broader patient population.

Key Players

• Medtronic plc

• 3M Company

• Becton Dickinson and Company

• Smiths Medical

• Stryker Corporation

• Arizant Healthcare Inc.

• GE Healthcare

• Cardinal Health, Inc.

• Paragon Medical

• Teleflex Incorporated

Numerous well-known businesses have implemented market expansion plans that emphasize strategic alliances and new product development. For example, Medtronic increased its revenue in this area by 10% in 2024 by introducing biodegradable surgical adhesives made especially for cardiovascular uses. In the meantime, Johnson & Johnson has boosted its hospital-based market penetration by 8% by working with specialty clinics to implement training programs on the proper use of fibrin glues.

Surgical Glues Market Future Outlook

• The future perspective of the Surgical Glues Market is optimistic, driven by several factors including the increasing number of surgical procedures worldwide and a growing geriatric population prone to chronic diseases.

• Innovations in adhesive formulations, such as more biocompatible and bio-resorbable options, are expected to enhance product efficacy and safety, further propelling market growth.

• The rising incidence of road accidents and chronic conditions globally continues to increase demand for effective wound closure solutions.

• Emerging markets, particularly in Asia-Pacific, are anticipated to exhibit the fastest growth due to expanding healthcare infrastructure and increased awareness about surgical glue benefits.

• Additionally, technological advancements tailored for robotic surgeries and minimally invasive procedures will open new avenues for surgical glue applications.

• Hospitals remain the primary end users, while ambulatory surgical centers are gaining traction as important growth segments.

• Despite challenges like high costs and alternative products, strategic collaborations and research initiatives by key players are likely to foster continuous innovation and market expansion in the coming years, thus making the surgical glue market a dynamic and growing sector in healthcare.

Historical Development

• For instance, according to the Centers for Disease Control and Prevention (CDC) in 2014, around 2.5 million people were hospitalized due to injuries. Moreover, replacement of conventional sutures and staples with surgical glues had exceptional characteristics such as increased bond strength, biocompatibility, versatility, and degradation.

• For instance, according to the TMC Innovation Institute, in 2017 around 50 million surgeries and around 30 million accidents occurred annually in the U.S., which needed some form of wound closure. Conventionally, wounds were closed using either suturing, stapling, or cauterization. However, critical challenges were associated with it such as post-surgery leakage out of suture and staple lines.

• For instance, in 2017, Sealantis was expected to launch its pipeline product Seal-V which was the fastest, safest, and most effective vascular sealant. Seal-V was a protein-free, strong, biocompatible vascular sealant that allowed precise control of the curing process for vascular surgeries.

Sources

• Primary Research interviews:

• Operating room nurses & surgical technicians

• Biomedical engineers

• R&D heads in medical device companies

• Databases:

• ScienceDirect

• ProQuest

• StatPearls

• Magazines:

• MedTech Insight

• Medical Product Manufacturing News

• The Journal of Medical Device Manufacturing

• Journals:

• Annals of Surgery

• Tissue Engineering

• Advanced Healthcare Materials

• Newspapers:

• The Times of India (Healthcare)

• The Hindu (Health)

• Financial Times (Healthcare & Pharma)

• Associations:

• Society for Biomaterials (SFB)

• World Health Organization (WHO)

• European Society of Biomaterials (ESB)