Ursodeoxycholic Acid Market, by Dosage Form (Solid and Liquid), by Mode of Extraction (Synthetic and Biological), by Application (Gallstones, Cystic Fibrosis, Liver Cirrhosis, and Others), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Trends, and Forecast to 2026

  • Published On : Oct 2018 |
  • Pages : 157 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Ursodeoxycholic Acid Market – Insights

Ursodeoxycholic acid (UDCA) is a bile acid taken as either a tablet or liquid to treat gallstones and to treat and prevent the progression of cystic fibrosis-related liver disorder. UDCA modifies the bile acid pool by decreasing levels of hydrophobic bile acids while increasing proportion of nontoxic hydrophilic bile acids. UDCA can delay development of gastroesophageal varices and progression to cirrhosis. Moreover it can improve long-term survival in patients with primary biliary cirrhosis.

Significant improvement in liver health can be achieved during UDCA therapy in patients with intrahepatic cholestasis of pregnancy, primary sclerosing cholangitis, nonalcoholic fatty liver disease, cystic fibrosis-associated liver disease, total parenteral nutrition-induced cholestasis, graft related liver disease, and in some pediatric cholestatic liver diseases.

The global ursodeoxycholic acid market size was valued at US$ 346.2 million in 2017, and is expected to witness a CAGR of 7.0% over the forecast period (2018 – 2026).

Global Ursodeoxycholic Acid Market Share (%) Analysis, By Application 2017

Source: Coherent Market Insights Analysis (2018)

Increasing prevalence of gall stones and cystic fibrosis is expected to drive growth of the ursodeoxycholic acid market

Ursodeoxycholic acid is increasingly being used for the treatment of chronic cholestatic liver diseases. Increasing prevalence of cystic fibrosis and gall stones is a major factor driving growth of the global ursodeoxycholic acid market during the forecast period. According to the Cystic Fibrosis Foundation 2015 data, around 30,000 people suffered from cystic fibrosis in the U.S. Moreover, around 1,000 new cases of cystic fibrosis are diagnosed in the country, annually. According to the American Gastroenterological Association 2017 report, gallstones is affecting 10-15% of the U.S. population annually, which accounts for around 25 million people.

Women are more likely to develop gallstones in comparison to men. High estrogen levels during pregnancy, birth control pills or hormone replacement therapy are the major factors that produce gallstones in women. Moreover, occurrence of gallstones is also high in older adults and individuals with a family history of gallstones. Surgery is the usual treatment for symptomatic gallstones, however treatment with ursodeoxycholic acid can dissolve smaller stones, which are made mainly of cholesterol.

Ursodeoxycholic Acid Market Restraints

However, some side effects of UDCA are expected to hinder growth of the ursodeoxycholic acid market. Diarrhea is the single most frequent adverse event during UDCA treatment in patients with gallstone disease. According to a study published in the National Center for Biotechnology Information (NCBI) in 2017, diarrhea incidence in gallstone disease patients prescribed with UDCA, was found to be in the range of 2%–9%. Other possible side effects of UDCA include, nausea, vomiting, itching or dry skin, headache, and sleep disturbances. Moreover, side effects of UDCA are evident in pregnant women and its use should be avoided during the first three months of pregnancy.

Ursodeoxycholic Acid Market - Regional Insights

On the basis of region, the global ursodeoxycholic acid market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Europe is expected to generate a significant revenue share in the global ursodeoxycholic acid market by 2026, owing to increasing government support for liver diseases treatment. For instance, the American Liver Foundation is a national, non-profit organization that is dedicated to the prevention, treatment, and cure of various liver diseases through research, education, and advocacy.

Global Ursodeoxycholic Acid Market Value (US$ Mn) & Y-o-Y Growth (%)  

 Source: Coherent Market Insights Analysis (2018)

Ursodeoxycholic Acid Market - Competitive Landscape

Key players operating in the global ursodeoxycholic acid market include, Abil Chempharma, Arcelor Chemicals, Biotavia Labs, Daewoong Chemical, Dipharma Francis, Erregierre, Grindeks, ICE, Mitsubishi Tanabe, Pharma Zell, Suzhou Tianlu, and Zhangshanbelling.

Ursodeoxycholic acid (UDCA) is a naturally occurring bile acid and is used to dissolve gallstones that are rich in cholesterol. It is also used to improve the flow of bile in primary biliary cirrhosis. UDCA solubilizes cholesterol gallstones and improves the liver function in case of cholestatic diseases. UDCA can be obtained from cholic acid, which is the most abundant and least expensive bile acid available.

Market Dynamics

Increasing incidence of gallstones and cystic fibrosis is expected to propel demand for UDCA, thereby driving the ursodeoxycholic acid market growth. According to a study published in the journal Gastroenterology, 2009, cholelithiasis, the presence of gallstones in the gallbladder, is estimated to occur in 10 – 15% of the adult population in the U.S. Although, gallstones can occur at any age, it is rare before the age of 30. A progressive increase in risk of cholelithiasis is observed with age and in patients over 50, the prevalence ranges is between 25-30%.

Moreover, prevalence of gallstones is two to three times higher in women than in men. According to the American College of Gastroenterology 2018 report, gallstones occur in around 20% of women by the age of 60. Moreover, women between the age of 20 and 60 years are three times more likely to develop gallstones than men.

Furthermore, increasing research studies conducted over the applications of UCDA in other disease indications is expected to fuel growth of the global ursodeoxycholic acid market. According to the University of Sheffield August 2018 study, UDCA improves mitochondrial dysfunction, which is known to be a causative factor for both sporadic and familial Alzheimer’s disease. However, side effects associated with the use of UDCA including diarrhoea, indigestion, headache, nausea, vomiting, unusual bleeding or bruising are expected to confine growth of the market during the forecast period.

Key features of the study:

  • This report provides in-depth analysis of the global ursodeoxycholic acid market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2018 – 2026, considering 2017, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global ursodeoxycholic acid market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include, Abil Chempharma, Arcelor Chemicals, Biotavia Labs, Daewoong Chemical, Dipharma Francis, Erregierre, Grindeks, ICE, Mitsubishi Tanabe, Pharma Zell, Suzhou Tianlu, and Zhangshanbelling
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The global ursodeoxycholic acid market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors, and suppliers for ursodeoxycholic acid market, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Global Ursodeoxycholic Acid Market, By Dosage Form:
    • Liquid
    • Solid
  • Global Ursodeoxycholic Acid Market, By Mode of Extraction:
    • Synthetic
    • Biological
  • Global Ursodeoxycholic Acid Market, By Application:
    • Gallstones
    • Cystic Fibrosis
    • Liver Cirrhosis
    • Others
  • Global Ursodeoxycholic Acid Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Dosage Form:
        • Solid
        • Liquid
      • By Mode of Extraction:
        • Synthetic
        • Liquid
      • By Application:
        • Gallstones
        • Cystic Fibrosis
        • Liver Cirrhosis
        • Others
  • Company Profiles
    • Abil Chempharma*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Arcelor Chemicals
    • Biotavia Labs
    • Daewoong Chemical
    • Dipharma Francis
    • Erregierre
    • Grindeks
    • ICE
    • Mitsubishi Tanabe
    • Pharma Zell
    • Suzhou Tianlu
    • Zhangshanbelling

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Dosage Form
      • Market Snippet, By Mode of Extraction
      • Market Snippet, By Application
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Clinical Studies
    • Epidemiology Analysis
    • PORTER’S Five Forces
  4. Global Ursodeoxycholic Acid Market, By Dosage Form, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2016 – 2026
      • Segment Trends
    • Solid
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Liquid
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  5. Global Ursodeoxycholic Acid Market, By Mode of Extraction, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2016 – 2026
      • Segment Trends
    • Synthetic
      •  Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Biological
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  6. Global Ursodeoxycholic Acid Market, By Application, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2016 – 2026
      • Segment Trends
    • Gallstones
      •  Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Cystic Fibrosis
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Liver Cirrhosis
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  7. Global Ursodeoxycholic Acid Market, By Region, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2016 – 2026
      • Regional Trends
    • North America
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • Northern Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Dosage Form, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Mode of Extraction, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2016 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Abil Chempharma
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Arcelor Chemicals
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Biotavia Labs
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Daewoong Chemical
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Dipharma Francis
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Erregierre
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Grindeks
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • ICE
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Mitsubishi Tanabe
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Pharma Zell
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Suzhou Tianlu
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Zhangshanbelling
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 22 market data tables and 25 figures on "Ursodeoxycholic Acid Market” - Global forecast to 2026”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Smiley face

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Smiley face

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Choose License Type

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

[email protected]

Key Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.