ALK positive lung cancer treatment is used for people suffering from lung cancer with Anaplastic Lymphoma Kinase (ALK) mutation (the EML4-ALK fusion gene). This gene mutation is due to gene rearrangement by fusion of two genes called as ALK and Echinoderm Microtubule-associated protein Like 4 (EML4). The ALK gene fusion was first reported in 2007, in Non-small cell lung cancer (NSCLC) patients.
ALK Positive Lung Cancer Treatment Market Drivers
New drug approvals for treatment of ALK positive lung cancer is expected to drive growth of the market. For instance, in August 2018, China National Drug Administration (CNDA) approved Alecensa (alectinib) of F. Hoffmann-La Roche Ltd., for treatment of ALK-positive lung cancer. Moreover, CNDA granted marketing authorization for Alecensa (alectinib), as monotherapy treatment for patients with anaplastic lymphoma kinase (ALK)-positive and advanced non-small cell lung cancer (NSCLC).
ALK Positive Lung Cancer Treatment Market Restraints
Development of rapid resistance to drugs is expected to limit growth of the ALK positive lung cancer treatment market. For instance, according to an Oncology Live February 2018 report, major challenge in drug development is rapid growth in resistance, which is responsible for slow patient recovery from disease. Moreover, according to an article published in Cancers journal, in August 2017, the mechanisms for resistance in drugs is tyrosine kinase mutations, and Epidermal Growth Factor Receptor (EGFR) activation. These bypass mechanisms of resistance are aggravating tumor cells, which in turn is restraining growth of the market.
ALK Positive Lung Cancer Treatment Market – Regional Analysis
On the basis of region, the global ALK positive lung cancer treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America region is expected to witness significant growth in the market, owing to increasing number of clinical trials operating in the U.S. For instance, TP Therapeutics, Inc., is undergoing clinical trial for TPX-0005 drug for treating ALK mutations. The study is expected to complete in December 2021.
Asia Pacific region is expected to witness the significant growth in the market, owing to increasing use of tobacco and smoking leading to lung cancer. According to an article published in Eastern Journal of medical Sciences 2017, lung cancer contributes around 6.8% of all cancers in India, representing the significant burden of lung cancer on country, which is contributing towards the cancer morbidity and mortality.
Key players operating in ALK positive lung cancer treatment market include F. Hoffmann-La Roche Ltd., Pfizer Inc., Novartis AG, TP Therapeutics, Inc., Bristol-Myers Squibb Company, and Eli Lilly and Company.
ALK Positive Lung Cancer Treatment Market – Taxonomy
Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:
In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.
Coherent Market Insights desk research is based on a principle set of research techniques:
Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:
Preliminary Data Mining
The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.
Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.
Coherent Statistical model
We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:
Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.
This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:
The primary research is conducted with the ecosystem players including, but not limited to:
Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.[email protected]
Talk to our research consultant to design an exclusive report as per your research needs.
We aim to fulfil client's research demands with tailored research solutions.
We aim to provide research studies in quickest turnaround time and in a much cost effective manner.
We cover each industry from supply and demand side with an aim to provide a most holistic research study.
We strive to provide most accurate and reliable research findings in our research reports.