Single cell genome sequencing involves isolating a single cell and amplifying and sequencing genes within that single cell. Sequencing single cell carries significant importance as individual cells can differ at great extent in size, protein levels, and expressed RNA transcripts. These variations could provide important insights about several research applications such as cancer research, stem cell biology, immunology, developmental biology, and neurology. Single-cell analysis enables a closer view of the gene expression of individual cells to understand their functions in complex tissues.
Kits and instruments based on technological platform such as Next Generation Sequencing (NGS), polymerase chain reaction (PCR), quantitative polymerase chain reaction (qPCR), and others provide high-throughput sequencing of individual cells. Single cell sequencing has significantly evolved with in-depth understanding of genomes and increasing genomic research to trace the root cause of many chronic diseases.
Single Cell Genome Sequencing Market Dynamics
Single cell genome sequencing is one of most focused area of research for finding cure for chronic disease such as cancer as it could help to observe tumor microenvironment. According to World Health Organization (WHO), cancer is one of leading non-communicable disease and second leading cause of death, worldwide. According to a report by International Age for Research on Cancer (IARC) in 2012, around 14.1 million new cases of cancer were registered with around 8.8 million death and around 32.6 million people are living with cancer in the year 2012.
Introduction of new therapies for the treatment of cancer such as personalized medicine (Immuno-oncology and others.) is expected to increase the adaption of single cell genomic sequencing for advancing research in order to observe cellular level changes in cancer cells.
Furthermore, application of single cell genomic sequencing in other diseases such as immune system disorder and infectious diseases (Tuberculosis, meningococcal disease, and others.) is a key factor contributing to the market growth. According to statistics given by Centers for Disease Control and Prevention 2017 Vital Signs, around 54.4 million U.S. adults suffer from arthritis – which is equivalent to 25% of the U.S. population. Rheumatoid arthritis which is leading autoimmune disorder holds significant share in the overall arthritis prevalence.
Continuous development in sequencing technologies is further expected to propel growth of the single cell genome sequencing market. PCR and next generation sequencing are rapidly emerging as preferred technology for several applications including single cell genomic sequencing. For instance, Oxford Nanopore, in 2017, launched two sequencing kits— for direct or PCR cDNA analysis that facilitate easy use and provide results in reduced time and cost.
Several collaborations amongst commercial companies and academic and research institutes is expected to propel the single cell genome sequencing market growth. For instance, in 2015, three single cell genomics centers were started in Sweden, Australia and the U.S—with an objective to facilitate R&D activities in single cell genome sequencing. The center in Australia was started with collaboration of Monash University, the University of Melbourne, the University of Newcastle and the Hudson Institute of Medical Research, and Fluidigm Corporation.
Single Cell Genome Sequencing Market - Regional Insights
On the basis of Geography, single cell genome sequencing market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be dominant in the market during forecast period. High prevalence of different types of cancer is witnessed in the U.S. According to a report by American cancer Society, 2018, cancer is the second leading cause of death after cardio vascular disease. The report further projected around 1.7 million new cases of cancer with around half million deaths, worldwide.
Single cell genome sequencing is utilized by several research institutes and commercial companies for revealing changes at gene level in single cell which could lead to potential therapies and access to develop new medicines.
Moreover, key players that offer cutting edge technologies such as NGS technology, q PCR technology and high commercial and academic research spending are present in the U.S, which is expected to accelerate the market growth.
Single Cell Genome Sequencing Market - Competitive Landscape
Key players operating in the single cell genome sequencing market include, Illumina, Inc., Fludigim Corporation, Thermo Fisher Scientific, F. Hoffmann-La Roche Ltd., Inc., QIAGEN, Bio-Rad Laboratories, 10x Genomics, Novogene, BGI, Oxford Nanopore Technologies, and Pacific Biosciences
Companies are focused on new product launches and collaborations to extend their market share. For instance,
Single Cell Genome Sequencing Market Taxonomy
On the basis of product type:
On the basis of technology:
On the basis of end users:
On the basis of geography:
Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:
In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.
Coherent Market Insights desk research is based on a principle set of research techniques:
Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:
Preliminary Data Mining
The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.
Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.
Coherent Statistical model
We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:
Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.
This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:
The primary research is conducted with the ecosystem players including, but not limited to:
Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.[email protected]
Talk to our research consultant to design an exclusive report as per your research needs.
We aim to fulfil client's research demands with tailored research solutions.
We aim to provide research studies in quickest turnaround time and in a much cost effective manner.
We cover each industry from supply and demand side with an aim to provide a most holistic research study.
We strive to provide most accurate and reliable research findings in our research reports.