Chronic pulmonary aspergillosis (CPA) is a serious long-term fungal disease of the lung with a worldwide prevalence. Chronic pulmonary aspergillosis (CPA) complicates conditions including tuberculosis, chronic obstructive pulmonary disease and sarcoidosis, and is associated with high morbidity and mortality. Chronic pulmonary aspergillosis (CPA) is characterized by slowly progressive destruction of lung parenchyma, in the form of single of multiple cavities, nodules, infiltrates or fibrosis, with or without an aspergilloma.
The global chronic aspergillosis treatment market is estimated to be valued at US$ 2,916.3 million in 2021 and is expected to exhibit a CAGR of 4.8 % during the forecast period (2021-2028).
Figure 1.Global Chronic Aspergillosis Treatment Market Share (%) in Terms of Value, By Drug Class, 2021
Increasing incidence and prevalence of aspergillosis is expected to drive the market growth during the forecast period.
Increasing prevalence of aspergillosis is expected to drive the global chronic aspergillosis treatment market growth over the forecast period. For instance, according to the National Organization for Rare Disorders, aspergillosis has been reported from all over the world in recent years. Allergic bronchopulmonary aspergillosis has been estimated to affect about one to four million people worldwide annually. Moreover, according to the same source, chronic pulmonary aspergillosis is estimated to affect about three million people worldwide every year.
|Base Year:||2020||Market Size in 2021:||US$ 2,916.3 Mn|
|Historical Data for:||2017 to 2020||Forecast Period:||2021 to 2028|
|Forecast Period 2021 to 2028 CAGR:||4.8%||2028 Value Projection:||US$ 4,056.4 Mn|
Astellas Pharma Inc., Abbott Laboratories, Pfizer Inc., Pulmocide Ltd., Johnson & Johnson, Mylan N.V., Glenmark Pharmaceuticals, Merck & Co., Inc., Mayne Pharma Group Limited, GlaxoSmithKline plc., PULMATRiX, Inc., F2G Ltd, Teva Pharmaceutical Industries Ltd., and Novartis International AG
|Restraints & Challenges:||
Figure 2.Global Chronic Aspergillosis Treatment Market Share (%), By Disease Type, 2021
Robust product pipeline of chronic aspergillosis is expected to drive the market growth during the forecast period.
Robust product pipeline for the treatment of chronic aspergillosis which are expected to launch during the forecast period is anticipated to drive the growth of the global chronic aspergillosis treatment market. For instance, on September 15, 2020, Regeneron Pharmaceuticals, a biopharmaceutical company, initiated phase III, a randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of dupilumab in patients with allergic bronchopulmonary aspergillosis. The study is estimated to be completed by October 23, 2023.
Global Chronic Aspergillosis Treatment Market– Impact of Coronavirus (COVID-19) Pandemic
According to Centers for Disease Control and Prevention, investigators in Spain and the U.S. added 20 new case reports to mounting evidence that patients with coronavirus disease 2019 (COVID-19) are at risk of developing pulmonary aspergillosis. The coronavirus (COVID 19) pandemic and lockdown in various countries across the globe have impacted the financial status of businesses in all sectors. Private healthcare sector is one of the sectors, which is majorly impacted by the COVID-19 pandemic. Moreover, coronavirus pandemic has negatively impacted the development, production, and supply of pharmaceutical products and affected growth of the medication used in treatment of chronic aspergillosis such as antifungal drugs and corticosteroids manufactured by various companies across the regions such as North America, Europe, and Asia Pacific. The supply and production of pharmaceutical products is also affected due to COVID-19 pandemic lockdown imposed globally. This lockdown has resulted in closure of industrial establishments, except manufacturing of essential commodities, and disruption in supply chain of the pharmaceutical products. Thus, COVID-19 pandemic has affected the economy in three main ways; 1) By directly affecting the production and demand; 2) By creating disruptions in distribution channels; and 3) By its financial impact on firms and financial markets. Thus, the impact of coronavirus (COVID-19) pandemic is expected to limit growth of the global chronic aspergillosis treatment market during the forecast period
Global Chronic Aspergillosis Treatment Market: Restraint
The major factors that are expected to hinder growth of the global chronic aspergillosis treatment market include increasing generic competition and complications associated with drugs used in the treatment of chronic aspergillosis. For instance, in November 2016, Ajanta Pharma, a pharmaceutical company, launched voriconazole tablets in 50-mg and 200-mg doses in the U.S. market. These tablets are the equivalent generic version of Vfend, an antifungal drug from Pfizer. Vfend is used to treat conditions such as invasive aspergillosis, candidemia, and serious infections caused by Scedosporium apiospermum and Fusarium species.
Major players operating in the global chronic aspergillosis treatment market include Astellas Pharma Inc., Abbott Laboratories, Pfizer Inc., Pulmocide Ltd., Johnson & Johnson, Mylan N.V., Glenmark Pharmaceuticals, Merck & Co., Inc., Mayne Pharma Group Limited, GlaxoSmithKline plc., PULMATRiX, Inc., F2G Ltd, Teva Pharmaceutical Industries Ltd., and Novartis International AG
Aspergillosis is a group of diseases that occur from aspergillus infection. Aspergillus is a fungus whose spores are present in the air, but does not normally cause illness. Individuals with damaged lungs, sensitive immune system, and allergies are more prone to aspergillus induced infection. Common aspergillus infections include invasive aspergillosis, non-invasive Allergic Pulmonary Aspergillosis (ABPA), and Chronic Pulmonary Aspergilloma (CPA). Azoles are the only oral drug with anti-aspergillus activity and itraconazole and voriconazole are considered as first-line drugs for chronic pulmonary aspergillosis.
Key players operating in the market are focusing on development and approval of novel therapeutics for the treatment of chronic aspergillosis, which is expected to offer a lucrative opportunity to the market players to launch innovative products in the market for the treatment of aspergillosis. For instance, In October 2017, Mylan N.V. launched caspofungin acetate for injection, one of the first generic versions of the U.S. pharma giant Merck's & Co’s Cancidas. It is indicated for invasive aspergillosis in patients who are refractory to or intolerant of other therapies. Furthermore, key companies in the market focusing on growth strategies such as FDA approvals which is expected to drive the growth of the market over forecast period. For instance, In January 2020, PULMATRiX, Inc. announced that the U.S. Food and Drug Administration (FDA) had granted Fast Track designation to PUR1900 (Pulmazole). The company's inhaled itraconazole antifungal candidate is developed to treat allergic bronchopulmonary aspergillosis (ABPA) in patients with asthma.
Key features of the study:
“*” marked represents similar segmentation in other categories in the respective section.
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