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  • Published On : Sep 2022
  • Code : CMI5254
  • Industry : Pharmaceutical
  • Pages : 227
  • Formats :

The immune system produces antibodies in response to pathogen invasion. Antigens are the collective term for the invasive bacteria, viruses, or other foreign molecules. Antibodies are proteins, or polypeptides which have specific antigen recognition sites. It is possible to have antibodies made using custom antibody production when an antibody is required against a particular antigen but it is not offered by a supplier. These antibodies can be either polyclonal or monoclonal, depending on how they are produced and harvested. Polyclonal antibodies are capable of recognizing multiple sites on an antigen. They are derived from different B-cell lineages. Monoclonal antibodies recognize only one epitope or site on an antigen, and are derived from a single B-cell line.

Global custom antibody service market is estimated to be valued at US$ 444.85 Million in 2022 and expected to reach US$ 930.46 million by 2030, witnessing a CAGR of 9.7 % over the forecast period (2022-2030).

Figure 1. Global Custom Antibody Service Market Share (%), By Region, 2022

Custom Antibody Service  | Coherent Market Insights

Market players are indulged in launching customized services for the development of custom antibodies that are used for research purposes, and this is expected to create lucrative growth opportunities in the custom antibody service market

The increase in organic strategies like new customized service launch is expected to drive the growth the market. For instance, in November 2020, AMSBIO, a leading provider of quality life science research reagents and services, announced the launch of development services for rabbit and mouse recombinant monoclonal antibodies. The DimAb development platform, a technology revolution for monoclonal antibody development, which differs from traditional hybridoma fusion methods, is the foundation for the creation of recombinant monoclonal antibodies. It can extract IgG genes from B cells of animals that have received an immunization. These antibodies aid in the creation and marketability of pharmaceuticals.

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Custom Antibody Service Market Report Coverage

Report Coverage Details
Base Year: 2021 Market Size in 2022: US$ 444.85 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2022 to 2030
Forecast Period 2022 to 2030 CAGR: 9.7% 2030 Value Projection: US$ 930.46 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Service Type: Antibody Development, Antibody Production, Downstream Antibody Services, Others (Antibody Purification Services, Antibody Fragmentation and Conjugation and Others)
  • By Product Type: Monoclonal Antibodies, Polyclonal Antibodies, Recombinant Antibodies
  • By Source: Rabbit, Chicken, Guinea pig, Goat, Mouse, Others (Rat and Others)
  • By Application: Oncology, Infectious diseases, Immunology, Neurobiology, Stem cells, Other (Cardiovascular Disease and Others)
  • By End Users: Pharmaceutical & biotechnology companies, Academic & research institutes, Contract research organizations
Companies covered:

Thermo Fisher Scientific, Inc., Genscript, Abcam plc., Cell Signaling Technology, Inc, Bio-Rad Laboratories, Inc., Merck KGaA, Agilent Technologies, Inc., BioLegend, Inc., ROCKLAND IMMUNOCHEMICALS, INC., ProMab, Innovagen AB, ProteoGenix, Bio-Techne., Creative Diagnostics., Sino Biological, Inc., RayBiotech Life, Inc., Abbiotec, Inc., ProSci Incorporated, Capralogics, Inc., and Boster Biological Technology

Growth Drivers:
  • Increasing launch of customized services for the development of custom antibodies
Restraints & Challenges:
  • Challenges involved in the production of customized antibodies

Figure 2. Global Custom Antibody Service Market Share (%) Analysis, By Product Type, 2022

Custom Antibody Service  | Coherent Market Insights

Advantages of using antibodies for various applications is projected to propel the market growth over the forecast period.

Advantages of antibodies is expected to increase their use for various applications such as research and development, production of therapeutics, etc.

According to the National Center for Biotechnology Information (NCBI): 2020, monoclonal antibodies and polyclonal antibodies are widely used in gold standard techniques such as ELISA, western blotting, flow cytometry, and other affinity based assays or isolation techniques. For ELISA, a monoclonal antibody helps detect a specific antigen of interest. Monoclonal antibodies can also help detect specific cells in flow cytometry. They are also useful for protein purification. Monoclonal antibody can further be used to bind a protein which can then be isolated from its solution.

Global Custom Antibody Service Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 outbreak in December 2019, the disease has spread to over 100 countries across the globe. The coronavirus (COVID 19) pandemic and consequent lockdown in various countries across the globe have impacted the financial status of businesses in all sectors. Supply chain and manufacturing activities have been disrupted globally, due to lockdowns implemented by governments of countries, restricted movement, and other COVID-19 safety precautions.

Identifying individuals infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a focal point throughout the coronavirus disease (COVID-19) pandemic. This has thus created a public health need for COVID-19 testing that is timely, reliable, and widely available.

Market players and academic or research institutes  are engaged in research and development activities for treatment of COVID-19 and due to this there has been increase in custom antibody services for COVID-19. This is expected to positively impact growth of the global custom antibody service market during the COVID-19 pandemic.

Global Custom Antibody Service Market: Restraint

Challenges involved in the production of customized antibodies is the major factor hampering the growth of the custom antibody services market. Some challenges includes:

  • Low yield: In vitro production cultures often yield less antibody/ml than in vivo ascitic fluid method
  • Cell death: Maintaining optimal cell growth and viability is essential for high antibody yields and an optimized process
  • Contamination: In vitro production cultures are subject to risks of contamination associated with long-term cell cultures
  • Time-consuming: In vitro production cultures often have to be maintained over a long period of time in order to yield desired quantities of antibodies

Antibodies are produced by the immune system in response to invading pathogens. The invading bacteria, virus, or other foreign molecules are collectively called as antigens. Antibodies are proteins, or polypeptides which have specific antigen recognition sites. Antibodies are formed by B-cells of the immune system. When an antibody is needed against a specific antigen, but it isn’t available from a supplier, it is possible to have antibodies made via custom antibody production. These antibodies are of two types depending on how they are generated and harvested: polyclonal or monoclonal. Polyclonal antibodies are capable of recognizing multiple sites on an antigen. They are derived from different B cell lineages. Monoclonal antibodies recognize only one epitope or site on an antigen, and are derived from a single B-cell line. There are six steps to polyclonal antibody production:

  1. Peptide design
  2. Peptide synthesis
  3. Animal immunization
  4. Serum collection
  5. Titer analysis
  6. Final antibody purification

Thus, key market player provide services in all or some of these above mentioned steps.

Market Dynamics

Increasing launches of new customized antibody services by key market players and advantages of using antibodies for various applications is expected to provide lucrative growth to Global Custom Antibody Service Market for the forecast period. In addition, increase in the funding by various organizations in R&D is expected to drive the growth of global custom antibody service market over the forecast period. For instance, according to an article published by R&D world on April 20, 2022, the U.S. industrial organizations are expected to collectively invest US$ 447 billion in R&D of health care. Moreover, the U.S. federal government is expected to invest US$ 181.4 billion in R&D of health care in 2022.

Key features of the study:

  • This report provides an in-depth analysis of the global custom antibody service market, market size (US$ Million), and compound annual growth rate (CAGR %) for the forecast period (2022-2030), considering 2021 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted By key players
  • It profiles key players in the global custom antibody service market based on the following parameters – company highlights, types portfolio, key highlights, financial performance, and market strategies
  • Key companies covered as a part of this study include Thermo Fisher Scientific, Inc., Genscript, Abcam plc., Cell Signaling Technology, Inc, Bio-Rad Laboratories, Inc., Merck KGaA, Agilent Technologies, Inc., BioLegend, Inc., ROCKLAND IMMUNOCHEMICALS, INC., ProMab, Innovagen AB, ProteoGenix, Bio-Techne., Creative Diagnostics., Sino Biological, Inc., RayBiotech Life, Inc., Abbiotec, Inc., ProSci Incorporated, Capralogics, Inc., Boster Biological Technology.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global custom antibody service market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the Global Custom Antibody Service Market

Detailed Segmentation:

  • Global Custom Antibody Service market, By Service Type:
    • Antibody Development
    • Antibody Production
    • Downstream Antibody Services
    • Others (Antibody Purification Services, Antibody Fragmentation and Conjugation and Others)
  • Global Custom Antibody Service market, By Product Type:
    • Monoclonal Antibodies
    • Polyclonal Antibodies
    • Recombinant Antibodies
  • Global Custom Antibody Service market, By Source:
    • Rabbit
    • Chicken
    • Guinea pig
    • Goat
    • Mouse
    • Others (Rat and Others)
  • Global Custom Antibody Service market, By Application:
    • Oncology
    • Infectious diseases
    • Immunology
    • Neurobiology
    • Stem cells
    • Other (Cardiovascular Disease and Others)
  • Global Custom Antibody Service market, By End Users:
    • Pharmaceutical & biotechnology companies
    • Academic & research institutes
    • Contract research organizations
  • Global Custom Antibody Service Market, By Region:
    • North America
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Country/Region
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Thermo Fisher Scientific, Inc.*
      • Company Highlights
      • Product Portfolio
      • Key Highlights
      • Financial Performance
      • Market Strategies
    • Genscript
    • Abcam plc.
    • Cell Signaling Technology, Inc
    • Bio-Rad Laboratories, Inc.
    • Merck KGaA
    • Agilent Technologies, Inc.
    • BioLegend, Inc.
    • ROCKLAND IMMUNOCHEMICALS, INC.
    • ProMab
    • Innovagen AB
    • ProteoGenix
    • Bio-Techne.
    • Creative Diagnostics.
    • Sino Biological, Inc.
    • RayBiotech Life, Inc.
    • Abbiotec, Inc.
    • ProSci Incorporated
    • Capralogics, Inc.
    • Boster Biological Technology

 “*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

Global custom antibody service Market is estimated to be valued at US$ 444.85 Million in 2022 and expected to exhibit a CAGR of 9.7% between 2022 and 2030.
Increasing launch of customized services for the development of custom antibodies is the major driving factor for the market.
The major type of products in market are monoclonal antibodies.
Challenges involved in the production of customized antibodies is a major factor restraining factor of the market growth.
Major players operating in the market include Thermo Fisher Scientific, Inc., Genscript, Abcam plc., Cell Signaling Technology, Inc, Bio-Rad Laboratories, Inc., Merck KGaA, Agilent Technologies, Inc., BioLegend, Inc., ROCKLAND IMMUNOCHEMICALS, INC., ProMab, Innovagen AB, ProteoGenix, Bio-Techne., Creative Diagnostics., Sino Biological, Inc., RayBiotech Life, Inc., Abbiotec, Inc., ProSci Incorporated, Capralogics, Inc. and Boster Biological Technology.

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