Any medicines that are taken and has effect on the digestive system are referred to as digestive drugs. These medicines can be over-the-counter (OTC) and prescription drugs. Medications that are commonly used for digestive conditions such as inflammatory bowel disease (IBD), crohn's disease, diarrhea, and constipation; belong to various drug classes such as 5-aminosalicylates, GI stimulants, laxatives and antacids among others. According to the classification of the drug, the medications have different mode of action. For instance, antacids facilitates in neutralising gastric acid and leads to inhibition of pepsin (a proteolytic enzyme), thus protecting the stomach mucosa.
Global digestive drugs market is estimated to be valued at US$ 52,594.8 million in 2022 and is expected to exhibit a CAGR of 5.86% during the forecast period (2022-2030).
Figure 1. Global Digestive Drugs Market in Terms of Value (US$ million), By Region, 2022
Global Digestive Drugs Market: Drivers
Key players operating in the market are getting approval to new digestive drugs, which is expected to drive the global digestive drugs market growth during the forecast period.
The approval of new therapeutic solutions for gastrointestinal disorders is further contributing to the market growth. For instance, in March 2020, Cipla received the U.S. Food and Drug Administration (FDA) approval for a generic acid reflux drug. The company received final approval for generic Esomeprazole, an oral suspension which is used for treatment of gastroesophageal reflux disease. Esomeprazole is available for various strengths such as 10mg, 20 mg and 40 mg from the U.S. Food and Drug Administration (U.S. FDA).
Figure 2. Global Digestive Drugs Market Share (%), By Type, 2022
Increasing prevalence of gastrointestinal disorders is expected to propel the market growth over the forecast period.
The increasing prevalence of gastrointestinal disorders is expected to boost the market growth over the forecast period. For instance, according an article published in July 2022, by the International Foundation for Gastrointestinal Disorders, Inc. (IFFGD), the prevalence in 2014 of Gastroesophageal Reflux Disease (GERD) in global populations is around 18 to 28% in North America, 9 to 26% in Europe, 9 to 33% in Middle East and 3 to 8% in East Asia among others.
Global Digestive Drugs Market– Impact of Coronavirus (COVID-19) Pandemic
COVID- 19 primarily affects the respiratory system; however, it also can affect multiple organs. The severity of COVID-19 is typically combined with a set of comorbidities such as hypertension, obesity, and diabetes, among others. In addition, COVID-19 can also be associated with gastrointestinal symptoms, such as diarrhea, vomiting, and abdominal pain during the early phases of the disease.
COVID-19 pandemic has drastically impacted the supply chain owing to multiple national lockdowns. Major challenges faced in the healthcare supply chains includes lack of quick access to centralized, consumable and gastrointestinal drugs API, imbalance in supply of raw materials, and risk of shortages in finished drug formulations among others. For instance, according to an August 2020 published paper in SAGE Publishing, in early March 2020, the Directorate General of Foreign Trade imposed strict restrictions on the export of 13 formulations and 13 active pharmaceutical ingredients (APIs). Hence, these factors had overall negative impact on the digestive drugs market.
|Base Year:||2021||Market Size in 2022:||US$ 52,594.8 Mn|
|Historical Data for:||2017 to 2020||Forecast Period:||2022 to 2030|
|Forecast Period 2022 to 2030 CAGR:||5.86%||2030 Value Projection:||US$ 82,969.4 Mn|
GlaxoSmithKline plc, AbbVie Inc. (Allergan), Takeda Pharmaceutical Company Limited, Pfizer Inc, AstraZeneca plc, Marksans Pharma, Tillotts Pharma AG, Salix Pharmaceuticals, Otsuka Pharmaceutical Co., Ltd., Merck & Co., Inc., Lexicon Pharmaceuticals, Inc., Bayer AG, Cadila Healthcare Ltd.
|Restraints & Challenges:||
Global Digestive Drugs Market: Restraint
Few drugs which are commonly used for the treatment of gastrointestinal disorders are often associated with adverse effects on any part of the gastrointestinal (GI) tract from mouth to colon. Hence, it is essential to obtain a detailed and accurate drug history of the patients presenting with GI complaints. Some of the adverse side effects resulting from medications such as antacids, histamine H2-receptor antagonists, muscarinic M1-receptor antagonists and proton pump inhibitors includes dry mouth, diarrhoea or constipation, stomach cramps, headache, nausea among others. Hence, the associated side effects with gastrointestinal therapeutics is likely to hamper the growth of digestive drugs market.
Major players operating in the global digestive drugs market include GlaxoSmithKline plc, AbbVie Inc. (Allergan), Takeda Pharmaceutical Company Limited, Pfizer Inc, AstraZeneca plc, Marksans Pharma, Tillotts Pharma AG, Salix Pharmaceuticals, Otsuka Pharmaceutical Co., Ltd., Merck & Co., Inc., Lexicon Pharmaceuticals, Inc., Bayer AG, Cadila Healthcare Ltd.
Digestive drugs are used to relieve gastrointestinal symptoms such as acid reflux, indigestion, and irritable bowel syndrome (IBS) among others. In addition, it is also used to treat other severe conditions such as Crohn's disease, ulcerative colitis, and hiatal hernia. The common digestive system diseases include symptoms such as abdominal pain, bloating, diarrhoea, constipation and heartburn. There are various gastrointestinal therapeutics that are used for treating various gastrointestinal conditions. For instance, acid reflux and indigestion are treated with antacids such as ranitidine and omeprazole. More severe conditions like ulcerative colitis and Crohn's disease are treated with medications such as budesonide, mesalazine and prednisolone. Few key market players manufacturing gastrointestinal drugs includes AbbVie, Alexion Pharmaceuticals, GlaxoSmithKline, Ironwood Pharmaceuticals and Janssen Pharmaceuticals among others.
Companies operating in digestive drugs market are launching new drugs which is contributing to growth of the digestive drugs market. For instance, in July 2022, JW Pharmaceutical, a South Korea based pharmaceutical company, launched Besticon a compound digestive medicine. It is composed of alverine citrate, simethicone and antispasmodic agent. Besticon is effective for patients suffering with irritable bowel syndrome, indigestion and other gastrointestinal issues. Similarly, in May 2021, Bristol Myers Squibb, a multinational pharmaceutical company received the U.S. Food and Drug Administration (FDA) approval for Zeposia for the treatment of severely active ulcerative colitis (UC). It is a sphingosine 1-phosphate (S1P) receptor modulator which reduces lymphocyte migration into the intestines.
Key features of the study:
“*” marked represents similar segmentation in other categories in the respective section.
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