Ranitidine Market, by Strength (75 mg, 150 mg, and 300 mg), by Form (Tablets, Syrup, and Injection), by Route of Administration (Oral and Intravenous), by Application (Intestinal & Stomach Ulcers, Gastroesophageal Reflux Disease (GERD), Esophagitis, Zollinger-Ellison Syndrome, and Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) - Size, Share, Trends, and Forecast till 2026

  • Published On : Sep 2018 |
  • Pages : 145 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Global Ranitidine Market – Global Industry Insights

Healthcare professionals have been keenly interested in the treatment of gastroesophageal reflux disease (GERD) and stomach & intestinal ulcer owing to its increasing prevalence. GERD is common health problem, which leads to serious medical complications and further huge medical expense in its diagnosis and treatment. The two most frequently observed symptoms associated with GERD are heartburn and acid regurgitation. Usually, over-the-counter antacids, proton pump inhibitor, and H-2 receptor blockers are used to decrease the effects of stomach acids or to block acid production.

Ranitidine is a histamine H2 antagonists and available as both over-the-counter (OTC) and prescription drug, indicated in the treatment of gastroesophageal reflux disease (GERD). Ranitidine decreases the acid production from stomach for up to 12 hours. Also, ranitidine is commonly used in erosive esophagitis, peptide ulcer disease, and Zollinger–Ellison syndrome. It could be taken orally or intravenously. 

The global ranitidine market size was valued at US$ 412.4 Mn in 2017, and is expected to witness a CAGR of 1.8% over the forecast period (2018 – 2026).

Global Ranitidine Market Share (%), By Application: 2018 & 2026

Source: Coherent Market Insights Analysis (2018)

Growing Research and Development (R&D) on Ranitidine is expected to Boost Market Growth  

Various government and private research organizations are increasingly engaged in research and development studies to increase the efficacy of ranitidine and examine possible potential of ranitidine to increase future scope of ranitidine market.

Furthermore, various clinical trials are currently undergoing to identify and compare efficacy between ranitidine and other proton pump inhibitors such as esomeprazole and rabeprazole to measure gastric acid reduction in stomach. With the result of these studies, the efficacy of ranitidine is expected to improve and offer better treatment regimes in reducing excessive gastric acid production in the near future.

For instance, in November 2015, a study to compare the efficacy of rabeprazole extended release (ER) 50 mg versus ranitidine 150 mg in treating erosive gastroesophageal reflux disease (eGERD) is currently in Phase III clinical stage.

 Global Ranitidine Market Share (%), By Form: 2018 & 2026

Source: Coherent Market Insights Analysis (2018)

Rising Cases of Various Gastric Ulcers and Digestive Diseases is expected to Increase Growth of the market  

High prevalence of gastroesophageal reflux disease (GERD), intestinal & stomach ulcers, esophagitis, heartburn, and other digestive diseases due to unhealthy lifestyle, changing dietary patterns will lead to increase in demand for ranitidine-based medications in the near future. According to Florida Hospital, 2018 U.S. data statistics, in the U.S. over 60 million adults suffer from acid reflux symptoms every month. Furthermore, the source states that each day an estimated 25 million of the 60 million adults suffers from acid reflux symptoms. Also, according to the same source, about 20% of people with acid reflux will develop gastroesophageal reflux disease (GERD) in the near future.

Heartburn with or without regurgitation is identified as one of the prime symptoms of gastroesophageal reflux disease (GERD). According to World Gastroenterology Organization (WGO), 2015, prevalence of GERD is rapidly increasing worldwide, with differences reported in prevalence ranging from 2.5% to 6.6% in Eastern Asia while slightly higher up to 13.8% to 25.8% in North America.    

The reason for high prevalence of GERD is not entirely clear, however, it appears to be correlated with increasing prevalence of obesity, and several dietary factors. In obese patients, excess belly fat exert more pressure on the stomach, which causes backflow of acid causing heartburn. Increasing number of obese patients across the globe will indirectly increase GERD cases and this is expected to fuel growth of ranitidine market. According to World Health Organization (WHO), in 2016, over 1.9 billion adults aged 18 years and above were overweight, of which over 650 million were obese, worldwide. Furthermore, GERD is associated with possible risk of Barrett’s esophagus: a premalignant condition that damages the esophagus tube.   

However, stringent regulatory guidelines of FDA in the manufacturing of finished drugs will limit growth of ranitidine market. For instance, in March 2018, the Ministry of Food and Drug Safety, South Korea banned the imports of 150 mg Zantac (ranitidine) supplied by GlaxoSmithKline (GSK) Korea, for 4 months (March to June 2018) due to its different shape and coatings. According to the same source, South Korea’s Ministry of Food and Drug Safety report, GSK violated Pharmaceutical Affairs Act by changing the approved shape of Zantac. Zantac is supposed to be white and round with thin film-coatings on both side, while GSK distributed Zantac with thick coated film and also coating around some of the tablets were slightly broken. Changes in color, taste, and packaging might hurt the safety and efficacy of drugs, which directly affects the quality of product.   

Furthermore, one of the major challenges in determining prevalence of GERD is to identify the patients’ suffering with the condition. Patients suffering with GERD-related symptoms do not consult healthcare professionals until the symptom gets severe. . Direct costs associated with GERD disease include costs of over-the-counter and prescription medications, physician office and hospital visits, surgical costs, and costs of treating other possible complications such as Barrett's esophagus and esophageal adenocarcinoma, which may result from the disease. This is expected to limit the growth of ranitidine market, over the forecasted period.    

Key players operating in the global ranitidine market include GlaxoSmithKline plc, Boehringer Ingelheim GmbH, Strides Pharma Science Limited (StridesShasun), Tocris Bioscience (R & D Systems), Merck KGaA, and Sun Pharmaceutical Industries Limited among others.

Ranitidine is a histamine type 2 (H2) receptor blocker drug available by prescription as well as over-the-counter (OTC). Ranitidine is used in treatment of intestinal & stomach ulcers, gastroesophageal reflux disease (GERD), and erosive esophagitis, and Zollinger-Ellison syndrome. Stomach ulcer or peptide ulcer causes open sores in the inner lining of stomach and upper portion of small intestine. Ranitidine helps to reduce excessive acid production in patient’s stomach. Increasing prevalence of risk factors to cause peptide ulcers in patients such as use of pain relievers, use of certain medications (steroids, low-dose aspirin, combination of selective serotonin reuptake inhibitors (SSRIs) with pain relievers), smoking, excessive alcohol consumption, untreated stress and easting of spicy foods; greatly increases the chance of developing ulcers.

Market Dynamics

Ranitidine market is expected to witness growth during the forecast period, owing to growing prevalence of gastroesophageal reflux disease (GERD) and stomach and intestinal ulcers, worldwide. For instance, a review study published in the Gut Journal in June 2014, estimated the range of GERD prevalence in global population, in 2014. This study reported GERD prevalence as 18%- 28% in North America, 9%-26% in Europe, 3%-8% in East Asia, 9%-33% in Middle East, 12% in Australia, and 23% in Latin America. According to this statistics, North America and Middle East are at higher risk to develop GERD disease.

Furthermore, higher efficacy and tolerability of ranitidine in suppression of stomach & intestinal ulcers is increasing the adoption of ranitidine-based medication in the market.   

Key features of the study:

  • This report provides in-depth analysis of ranitidine market and provides market size (US$ Million) and Compound Annual Growth Rate (CAGR %) for the forecast period (2018 – 2026), considering 2017, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches and approval, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global ranitidine market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies and future plans
  • Key companies covered as a part of this study include GlaxoSmithKline plc, Boehringer Ingelheim GmbH, Strides Pharma Science Limited (Strides Shasun), Tocris Bioscience (R&D Systems), Merck KGaA, and Sun Pharmaceutical Industries Limited among others.
  • Insights from this report would allow marketers and management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
  • The global ranitidine market report caters to various stakeholders in this industry including investors, suppliers, ranitidine-based product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through the various strategy matrices used in analyzing the ranitidine market.

Detailed Segmentation:

  • Global Ranitidine Market, By Strength:
    • 75 mg
    • 150 mg
    • 300 mg
  • Global Ranitidine Market, By Form:
    • Tablet
    • Syrup
    • Injection
  • Global Ranitidine Market, By Route of Administration:
    • Oral
    • Intravenous
  • Global Ranitidine Market, By Application:
    • Intestinal & Stomach Ulcers
    • Gastroesophageal Reflux Disease (GERD)
    • Esophagitis
    • Zollinger-Ellison Syndrome
    • Other Application  
  • Global Ranitidine Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Global Ranitidine Market, By Geography:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application:
        • Intestinal & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Europe
      • By Country:
        • Germany
        • France
        • Italy
        • UK
        • Spain
        • Russia
        • Rest of Europe
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application:
        • Intestinal & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Asia Pacific
      • By Country:
        • China
        • India
        • Japan
        • South Korea
        • Australia
        • Rest of Asia Pacific
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application
        • Intestin:al & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application:
        • Intestinal & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Latin America
      • By Country:
        • Brazil
        • Argentina
        • Mexico
        • Rest of Latin America
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application:
        • Intestinal & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Strength:
        • 75 mg
        • 150 mg
        • 300 mg
      • By Form:
        • Tablet
        • Syrup
        • Injection
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Application:
        • Intestinal & Stomach Ulcers
        • Gastroesophageal Reflux Disease (GERD)
        • Esophagitis
        • Zollinger-Ellison Syndrome
        • Other Application
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
  • Company Profiles
    • GlaxoSmithKline plc *
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Developments
      • Strategies
    • Boehringer Ingelheim GmbH
    • Strides Pharma Science Limited (Strides Shasun)
    • Tocris Bioscience (R & D Systems)
    • Merck KGaA
    • Sun Pharmaceutical Industries Limited

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Strength
      • Market Snippet, By Form
      • Market Snippet, By Route of Administration
      • Market Snippet, By Application
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Regulatory Scenario
    • Market Trends
    • Epidemiology
    • Approvals/Launches
    • Mergers/ Acquisition
    • Strategic Collaborations
    • PEST Analysis
  4. Global Ranitidine Market, By Strength, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
      • Segment Trends
    • 75 mg
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • 150 mg
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • 300 mg
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  5. Global Ranitidine Market, By Form, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
      • Segment Trends
    • Tablets
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Syrup
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Injection
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  6. Global Ranitidine Market, By Route of Administration, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
      • Segment Trends
    • Oral
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Intravenous
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  7. Global Ranitidine Market, By Application, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
      • Segment Trends
    • Intestinal & Stomach Ulcers
      • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
    • Gastroesophageal Reflux Disease (GERD) 
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Esophagitis
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Zollinger-Ellison Syndrome
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  8. Global Ranitidine Market, By Distribution Channel, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 - 2026
      • Segment Trends
    • Hospital Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Retail Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
    • Online Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
  9. Global Ranitidine Market, By Region, 2016 - 2026 (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, For Region, 2017 - 2026
    • North America
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Strength, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Form, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Application, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026 (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  10. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • GlaxoSmithKline plc
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Boehringer Ingelheim GmbH 
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Strides Pharma Science Limited (Strides Shasun)
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Tocris Bioscience (R & D Systems)
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Merck KGaA
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Sun Pharmaceutical Industries Limited
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
    • Analyst Views
  1. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 22 market data tables and 25 figures on "Ranitidine Market - Global forecast to 2026”.

Research Methodology

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