RESEARCH ANTIBODIES MARKET ANALYSIS

Research antibodies act as vital tools in laboratory techniques such as western blotting etc. that are conducted for research purposes. Due to their high specificity and sensitivity, antibodies and associated reagents make an important tool that aids in the detection of molecules and its analysis, which allows researchers to draw conclusions related to drug target, disease occurrence, and immune system pathways. Research antibodies are essential detecting techniques used by scientists. When attempting to understand why a cell function has gone wrong, antibodies can be used to mark and identify specific proteins that are present in the diseased cell at a specific stage of the disease life cycle.

Global Research Antibodies Market - Impact of the Coronavirus (COVID-19) Pandemic

Coronavirus (COVID-19) outbreak was first reported on December 31, 2019, in Wuhan, China. The World Health Organization declared COVID-19 as pandemic on March 11, 2020. According to the Coronavirus (COVID-19) Weekly Epidemiological Update by the World Health Organization, over 610 million cases and 6.51 million deaths due to coronavirus (COVID-19) were reported till September 22, 2022, across the globe.

Impact of COVID-19 on Demand and Supply of Research Antibodies

The COVID-19 pandemic and lockdown in various countries across the globe has impacted the financial status of businesses across all sectors including private healthcare sector. The COVID-19 pandemic has impacted the entire supply chain of the healthcare industry mainly due to strict lockdown in several regions. The COVID-19 pandemic has affected the economy of various regions across the globe in three main ways; 1) by directly affecting the production and demand; 2) by creating disruptions in distribution channels; and 3) through its financial impact on companies and financial markets. Several countries such as Thailand, Indonesia, and Singapore are facing problems with regards to transportation and distribution of healthcare products.

However, Coronavirus (COVID-19) pandemic is expected to positively impact growth of the global research antibodies market during the forecast period. For instance, in February, 2022, U.S. Food and Drug Administration (FDA), granted an emergency use authorization (EUA) of novel monoclonal antibody against the omicron variant for the treatment of COVID-19. EUA was authorized for mild to moderate COVID-19 in adults and children (12 years of age and older) who weigh at least 40 kilograms (88 pounds) and patients who have a positive COVID-19 test.

Global research antibodies market is estimated to be valued at US$ 3,574.6 Mn in 2022, and is expected to exhibit a CAGR 5.9% over the forecast period (2022-2030).

Figure 1: Global Research Antibodies Market Share (%) Analysis, By Product Type, 2022

Increasing research and development activities related to research antibodies are expected to drive the growth of market over the forecast period.

Increasing research and development activities related to research antibodies are expected to fuel growth of the global research antibodies market over the forecast period. For instance, according to a research article published in the journal eLife, non-profit, open access, scientific journal for the biomedical and life sciences, in March 2022, the study was conducted by researchers at the University of Washington, the Max Planck Institute for Dynamics and Self-Organization, and the University of Cologne on broadly neutralizing antibodies, or bNAbs (Broadly Neutralizing Antibodies) and it was observed that bNAbs could be used to treat HIV (Human Immunodeficiency Virus) while reducing the risk of the spreading virus. The study demonstrates that computational methods for selecting combinations of bNAbs based on viral genetics will help prevent viral escape, increasing the efficacy of HIV treatment.

Increasing product launches and approvals by market players are expected to drive growth of the global research antibodies market over forecast period.

Market players are engaged in product approvals, which is expected to boost the global research antibodies market growth over the forecast period. For instance, on January 21, 2020, Horizon Therapeutics plc, a biopharmaceutical company focused on researching, developing, and commercializing medicines, received the U.S. FDA (Food and Drug Administration) approval for the Tepezza (TM) (teprotumumab-trbw), therapeutic monoclonal antibody for the Treatment of Thyroid Eye Disease (TED). TED is a severe, progressive, and eyesight-threatening uncommon autoimmune condition that is accompanied by proptosis (eye bulging), diplopia (double vision), blurred vision, pain, inflammation, and facial disfigurement. Tepezza is the first and only medication for TED to get the U.S. FDA (Food and Drug Administration) approval.

Restraint- Global Research Antibodies Market

Challenges associated with storage conditions of antibodies is expected to hamper the growth of global research antibodies market over forecast period, challenges include –

• Monoclonal antibodies should be stored at -20°C in 50% glycerol
• Polyclonal antibodies should be stored at -20°C up to -80°C
• The major problem encountered during storage is contamination with bacteria or fungi 
• When stored for a long period of time, some antibody solutions may produce an insoluble lipid component 
• Undiluted antibodies should always be aliquoted prior to storage at -20 °C to minimize repeated freeze/thaw cycles that can denature antibody

Global Research Antibodies Market – Regional Analysis

On the basis of region, the global research antibodies market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

North America is expected to be the most lucrative region in the global research antibodies market, owing to increasing cases of lung cancer in the U.S. For instance, according to Centers of Disease Control and Prevention, in 2019, 221,097 new cases of lung and bronchus cancer were reported, and 139,601 people died of this cancer in the U.S.

Europe is expected to witness significant growth in the forecast period, owing to increasing approvals for monoclonal antibodies for the treatment of diseases. For instance, in December 2021, Vir Biotechnology, Inc., U.S.-based Biotechnology Company and GlaxoSmithKline plc. a British multinational pharmaceutical and biotechnology company announced that the European Commission (EC) approved Xevudy (sotrovimab) for commercialization for the early treatment of COVID-19. Sotrovimab is now approved in the European Union (EU) for the treatment of adults and adolescents with COVID-19 who do not require supplemental oxygen and are at elevated risk of advancing to severe COVID-19 (aged 12 years and above and weighing at least 40kg).

Figure 2: Global Research Antibodies Market Value (US$ Mn), by Region, 2022

Global Research Antibodies Market – Competitive Landscape

Major players operating in the global research antibodies market include Thermo Fisher Scientific Inc, Bio-rad Laboratories, Lonza Group, Merck Millipore, Cell Signalling Technology Inc., F.Hoffmann La Roche Ltd., Novartis AG, Takeda Pharmaceutical Company, Agilent Technologies, Danaher Corporation, BioLegend Inc., Illumina and Phoenix Pharmaceuticals.