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  • Published On : Apr 2023
  • Code : CMI2448
  • Pages :154
  • Formats :
      Excel and PDF
  • Industry : Biotechnology

The  global stem cell cartilage regeneration market is estimated to be valued at US$  403.5 million in 2023 and is expected to exhibit a CAGR of 9.2% during the forecast period (2023-2030).

Analysts’ Views on Global Stem Cell Cartilage Regeneration Market:  

Increasing research and development activities is expected to drive the global stem cell cartilage regeneration market over the forecast period. For instance, in February 2021, data was published in the National Center for Biotechnology Information (NCBI), according to which, in the field of articular cartilage regeneration and osteoarthritis (OA) treatment, research involving stem cells has moved from the laboratory to the clinic. However, several problems remain that restrict the application of tissue-engineered cartilage involving stem cells.

Figure 1. Global Stem Cell Cartilage Regeneration Market Share (%), By  Stem Cell Type, 2023

STEM CELL CARTILAGE REGENERATION MARKET

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Global Stem Cell Cartilage Regeneration Market – Driver

Increasing the number of cartilage disorders such as osteoarthritis and destruction of articular cartilage is expected to drive the market over the forecast period. For instance, in August 2020, data was published in the NCBI, according to which currently 52.2 million Americans are diagnosed with arthritis, and this is estimated to rise to 78.4 million by 2040, for these disorders, the most common type is osteoarthritis (OA).

Figure 2. Global Stem Cell Cartilage Regeneration Market  (US$ Million), By Region, 2023

STEM CELL CARTILAGE REGENERATION MARKET

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Global Stem Cell Cartilage Regeneration Market- Regional Analysis

On the basis of region, the global stem cell cartilage regeneration market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Out of which the North America is expected to be the most lucrative region for growth of the stem cell cartilage regeneration market over the forecast period, due to the high presence of key players in the region.

Global Stem Cell Cartilage Regeneration Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.

COVID-19 affected the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, the U.A.E., Egypt, and others are facing problems with the transportation of drugs from one place to another.

However, the COVID-19 pandemic had a positive impact on the global stem cell cartilage regeneration market. For instance, in September 2020, Stanford University along with the Chan Zuckerberg Biohub, a research organization, and a group of collaborators announced that they had developed a low-cost system to collect samples for COVID-19 testing and monitor populations for the disease

COVID-19 affected the global stem cell cartilage regeneration market positively. For instance, in November 2021, data was published in the National Center for Biotechnology Information (NCBI), according to which the lower rate of death and milder symptoms of COVID-19 infection in children and pregnant women are consistently reported across different regions of the world. Active stem cells (with a low ACE/ACE2 expression ratio) are specific to children and pregnant women.

Stem Cell Cartilage Regeneration Market Report Coverage

Report Coverage Details
Base Year: 2022 Market Size in 2023: US$ 403.5 Mn
Historical Data for: 2017 to 2021 Forecast Period: 2023 to 2030
Forecast Period 2023 to 2030 CAGR: 9.2% 2030 Value Projection: US$ 746.2 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Stem Cell Type: Hematopoietic Stem Cells (HSCs), Pluripotent Stem Cells (iPSC/ESCs), Mesenchymal Stem Cells (MSCs)
  • By Treatment: Microfracture, Osteochondral Transplant, Autologous Chondrocyte Implantation, Stem Cell Injections  
  • By End User: Hospitals, Ambulatory Surgical Centers
Companies covered:

Theracell Advanced Biotechnology Ltd., Orthocell Ltd., Xintela AB, CellGenix GmbH, Merck KGaA, Osiris Therapeutics, Inc., BioTissue SA, and Vericel Corporation., and other prominent players 

Growth Drivers:
  • Increasing the number of cartilage disorders such as osteoarthritis 
Restraints & Challenges:
  • High cost of the cartilage surgeries

Global Stem Cell Cartilage Regeneration Market Segmentation:

The global stem cell cartilage regeneration market report is segmented into stem cell type, treatment, end user, and region  

Based on Stem Cell Type, the market is segmented into hematopoietic stem cells (HSCs), Pluripotent Stem Cells (iPSC/ESCs), and Mesenchymal Stem Cells (MSCs). Out of which the Pluripotent Stem Cells (iPSC/ESCs) segment is expected to hold a dominant position in the global stem cell cartilage regenartion market over the forecast period.

Based on Treatment, the market is segmented into microfracture, osteochondral transplant, Autologous Chondrocyte Implantation, Stem Cell Injections. Out of which the osteochondral transplant segment is expected to hold a dominant position in the global stem cell cartilage regeneration market over the forecast period.       

Based on End User, the market is segmented into hospitals and ambulatory surgical centers. Out of which the hospital segment is expected to be dominant in the global stem cell cartilage regeneration market over the forecast period.

Global Stem Cell Cartilage Regeneration Market Cross Sectional Analysis

In stem cell type pluripotent stem cells is expected to dominate the global stem cell cartilage regeneration market over the forecast period. For instance, in September 2020, data was published in the springer nature journal, according to which pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to regenerate or replace functionally impaired tissues. Since the introduction of induced pluripotent stem cell technology in 2006, the number of scientific publications on this topic has constantly been increasing.

Global Stem Cell Cartilage Regeneration Market: Key Developments

Increasing adoption of minimally invasive surgical procedures is expected to drive the growth of the  global stem cell cartilage regeneration market. Stem cell therapy for knees, a minimally invasive procedure has the potential to decrease inflammation, halt the progression of arthritic damage, repair joint cartilage, and delay or avoid knee replacement surgery. Injection of progenitor cells, especially mesenchymal stem cells (MSCs) is found to be an effective and better solution for repairing degenerative cartilage compared to the implantation of differentiated cells such as articular cartilage.

Global Stem Cell Cartilage Regeneration Market: Restraint

High cost of the cartilage surgeries

One of the major factors that hampering the growth of stem cell cartilage regeneration is the high cost of the surgeries, which cost around or the average cost of the knee replacement procedure is cost around US$ 16,000, which costliest for the average population

Global Stem Cell Cartilage Regeneration Market - Key Players

Major players operating in the global stem cell cartilage regeneration market include Theracell Advanced Biotechnology Ltd., Orthocell Ltd., Xintela AB, CellGenix GmbH, Merck KGaA, Osiris Therapeutics, Inc., BioTissue SA, and Vericel Corporation, and other prominent players

Definition: Cartilage injuries are typically caused by trauma, chronic overload, and autoimmune diseases. Owing to the avascular structure and low metabolic activities of chondrocytes, cartilage generally does not self-repair following an injury. Currently, clinical interventions for cartilage injuries include chondrocyte implantation, microfracture, and osteochondral transplantation. However, rather than restoring cartilage integrity, these methods only postpone further cartilage deterioration. and irritative urinary symptoms and can ultimately impair renal function.

Frequently Asked Questions

The global stem cell cartilage regeneration market is estimated to be valued at US$ 403.5 million in 2023 and is expected to exhibit a CAGR of 9.2% between 2023 and 2030.

Increasing the number of cartilage disorders such as osteoarthritis is expected to drive the market 

Pluripotent stem cells (iPSC/ESCs) is the leading stem cell type segment in the market.

High cost of cartilage replacement is the major factor that is hampering the growth of the market

Major players operating in the market include Theracell Advanced Biotechnology Ltd., Orthocell Ltd., Xintela AB, CellGenix GmbH, Merck KGaA, Osiris Therapeutics, Inc., BioTissue SA, and Vericel Corporation

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