Wound Care Biologics Market - by Product Type (Biologic Skin Substitutes, Enzyme Based Formulations, and Growth Factors), by Application (Chronic Wounds and Acute Wounds), by End User (Hospitals, Clinics, Ambulatory Surgical Centers, and Home Care Settings), and by Region - Global Industry Insights, and Forecast to 2025

  • Published On : Apr 2018 |
  • Pages : 183 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Wound Care Biologics Market – Experience the Power of Effective Healing

Wound care biologics are bioengineered products used for non-healing wounds of the lower extremity.  Demand for wound care biologic products is expected to increase significantly as early intervention of diabetic ulcer can prevent severe complications such as infection, hospitalization, and amputation. Wound care biologics market is expected to gain significant traction, as the commercially available skin substitutes have clinical and experimental evidence of efficacy in wound healing.

The global wound care biologics market was valued at US$ 1.2 billion in 2016 and is expected to exhibit a robust CAGR of 6.9% over the forecast period (2017–2025).

Figure 1. Global Wound Care Biologics Market Value (US$ Mn), by Region, 2016

wound care biologics market

Source: Coherent Market Insights (2018)

High prevalence of diabetes is expected to aid in growth of the market

The wound care biologics market is expected to gain significant traction, with rise in global prevalence of diabetes, as diabetic patients are prone to developing diabetic ulcers. According to the Global Diabetes Community, 2017, an estimated 422 million adults are living with diabetes globally, and this is expected to increase to 642 million by 2040. Also, according to the Journal of Foot and Ankle Surgery, 2016, increasing number of diabetic patients has led to increased burden of diabetic complications, where peripheral neuropathy, foot ulceration, and Peripheral Arterial Disease (PAD) is twice as common for diabetic patients as compared to non-diabetics, affecting 30% of the diabetics aged 40 years and above. The Advances in Wound Care Journal, 2015, also stated that 15%–20% of the diabetic population is likely to develop chronic, non-healing foot wounds. Thus, wound care biologic products provides patients with a cost effective option for managing chronic wounds, thereby reducing economic burden of the patients.

However, high cost of skin substitutes and related biologics is a major hindrance for growth of the market. For instance, according to the Advances in Skin Substitutes Journal, 2014, cost for each 1% body surface area covered with Epicel, is estimated to be over US$ 13,000. This in turn, leads to increasing adoption of alternative and cost effective wound care products, which is expected to negatively affect growth of the market.

Asia Pacific market to exhibit fastest growth over the forecast period

Asia Pacific is expected to exhibit significant growth in the global wound care biologics market over the forecast period. This is owing to high prevalence of diabetic patients in Asian countries. According to the Indian Diabetes Research Foundation, 2016, around 60% of the world’s population suffering from diabetes lives in Asia, with around one-half in China and India combined. The Foundation also states that Western Pacific reported over 138.2 million people suffering from diabetes, the number for which is expected to rise to 201.8 million by 2035.

Moreover, rising medical tourism in Asia Pacific is a major driver for growth of the market. The number of foreign patients is increasing, owing to affordable treatment facilitates at hospitals for wound care management. According to the survey by Brink Global Risk Center, 2017, around 4 million medical tourists traveled to India for health care services, 3.5 million foreign patients travelled to Thailand and 900,000 patients to Singapore in 2016, with the number expected to grow by 10%–14% by 2020.

Increasing incidence of chronic wounds and ulcers to accelerate the market growth          

Chronic wounds have a significant impact on the health and quality of life of patients and their families, causing pain, emotional stress, restriction on daily activities, depression, distress, and anxiety, with prolonged hospital stay and chronic morbidity. According to the Advances in Wound Care Journal, 2015, chronic leg and foot ulcers last for around 12 months on an average, with recurrence affecting up to 65% of patients, leading to loss of function and decreased quality of life. It is also a significant cause of morbidity. Rising incidence of traumatic events such as accidents and fire accidents causing burns, systemic illness, antibiotic resistant, chronic disease, surgery, and impaired mobility are the prevailing factors resulting in increasing incidence of chronic wounds. The World Health Organization (WHO) also states that burns are the leading cause of morbidity, including prolonged hospitalization, disfigurement, and disability-adjusted life-years (DALYs) lost in low- and middle-income countries. Therefore, these factors are expected to be major factor aiding ion growth of the market over the forecast period.

North America is expected to be dominant region in the wound care biologics market, owing to rising prevalence of chronic non-healing wounds which pose an economic burden to the healthcare system. According to the American Diabetes Association, 2016, the average cost of healing a single foot ulcer is US$ 8,000 and that of a major amputation is $45,000. Furthermore, venous leg ulcers are the most common wound type in the U.S., affecting almost 2 million people.

Major players operating in the global wound care biologics market are Smith & Nephew Plc., Organogenesis, Inc., Integra Lifesciences Holdings Corporation, Skye Biologics, Alphatec Holdings, Inc., Solsys Medical LLC, Amino Technology LLC, and Osiris Therapeutics, Inc. 

Wound care biologic products facilitates in innate repair mechanisms, and involves the use of active biological agents such as animal and plant-derived active biomolecules, which exhibit antioxidant, antimicrobial, or anti-inflammatory properties. Wound care biologic dressings are increasingly being used in post surgeries and severe trauma cases as they provide moist healing environment aiding heat loss, protein and electrolyte loss for faster healing, and prevent bacterial contamination. Biologic skin substitute products include tissue-engineered products, which are designed to either temporarily or permanently replace the altered skin. Skin substitutes are commonly used products for wound management and have application for treating various ailments such as pressure ulcers, diabetic neuropathic ulcers, and vascular insufficiency ulcers.

Market Dynamics

Increasing incidences of chronic ulcers, owing to rising prevalence of diabetes, increasing surgical procedures, and rise in trauma cases are major driving factors for growth of wound care biologics market. According to the survey by World Health Organization, 2014, injuries resulting from traffic collisions, drowning, poisoning, falls or burns account for 9% of the global mortality. Also, according to a study by BMJ Journal Injury Prevention, 2013, an estimated 973 million people sustained injuries that warranted some type of healthcare and 4.8 million people died from injuries. The Journal also stated that major injury causes included road injury (29.1%), self-harm (17.6%), falls (11.6%), and interpersonal violence (8.5%). Manufacturers are also focused on extensive research and development to develop new products and expand their product portfolio. For instance, in 2016, Integra LifeSciences Holdings Corporation received FDA approval for Integra Dermal Regeneration Template (IDRT) for the treatment of diabetic foot ulcers that is marketed under the name of Integra Omnigraft Dermal Regeneration Matrix. Moreover, public awareness for biologics has positively contributed to the market growth, as people are opting for enhanced medical care for preventing wounds to minimize the morbidity associated with the formation of chronic wounds. However, higher cost of the biologics and stringent regulatory approvals for launch of innovative tissue engineered products are hindering growth of the wound care biologics market.

Key features of the study:

  • This report provides in-depth analysis of wound care biologics market and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR %) for the forecast period (2017–2025), considering 2016 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global wound care biologics market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, and strategies, and future plans
  • Key companies covered as a part of this study include Smith & Nephew Plc., Organogenesis, Inc., Integra Lifesciences Holdings Corporation, Skye Biologics, Alphatec Holdings, Inc., Solsys Medical LLC, Amino Technology LLC, and Osiris Therapeutics, Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
  • The global wound care biologics market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the wound care biologics market

Detailed Segmentation:

  • Global Wound Care Biologics Market, By Product Type:
    • Biologic Skin Substitutes
    • Enzyme Based Formulations
    • Growth factors
  • Global Wound Care Biologics Market, By Application:
    • Chronic Wounds
      • Diabetic Foot Ulcers
      • Venous Leg Ulcers
      • Pressure Ulcers
    • Acute Wounds
      • Surgical Wounds
      • Burns
  • Global Wound Care Biologics Market, By End User:
    • Hospitals
      • In-patient Settings
      • Out-patient Settings
    • Clinics
    • Ambulatory Surgical Centers
    • Home Care Settings
  • Global Wound Care Biologics Market, By Geography:
    • North America
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Product Type:
        • Biologic Skin Substitutes
        • Enzyme Based Formulations
        • Growth factors
      • By Application:
        • Chronic Wounds
          • Diabetic Foot Ulcers
          • Venous Leg Ulcers
          • Pressure Ulcers
        • Acute Wounds
          • Surgical Wounds
          • Burns
      • By End User:
        • Hospitals
          • In-patient Settings
          • Out-patient Settings
        • Clinics
        • Ambulatory Surgical Centers
        • Home Care Settings
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Smith & Nephew Plc.*
      • Company Overview
      • Product Portfolio
      • Key Highlights
      • Financial Overview
      • Market Strategies
    • Organogenesis, Inc.
    • Integra Lifesciences Holdings Corporation
    • Skye Biologics
    • Alphatec Holdings, Inc.
    • Solsys Medical LLC
    • Amino Technology LLC
    • Osiris Therapeutics, Inc.

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
      • Industry Trends
    • Technological Advancements
    • Regulatory Scenario
    • Reimbursement Scenario
    • Key Highlights
    • PEST Analysis
    • Epidemiology
    • Impact Analysis
  4. Global Wound Care Biologics Market, By Product Type, 2015–2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2015 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016–2025
      • Segment Trends
    • Biologic Skin Substitutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
    • Enzyme Based Formulations
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
    • Growth Factors
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
  5. Global Wound Care Biologics Market, By Application, 2015–2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2015 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016–2025
      • Segment Trends
    • Chronic Wounds
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
      • Segment Trends
        • Diabetic Foot Ulcers
        • Venous Leg Ulcers
        • Pressure Ulcers
    • Acute Wounds
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
      • Segment Trends
        • Surgical Wounds
        • Burns
  6. Global Wound Care Biologics Market, By End User, 2015–2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2015 and 2025 (%)
      • Y-o-Y Growth Analysis, 2016–2025
      • Segment Trends
    • Hospitals
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
      • Segment Trends
        • In-patient Settings
        • Out-patient Settings
    • Clinics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
    • Ambulatory Surgical Centers
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
    • Home Care Settings
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2015–2025, (US$ Million)
  7. Global Wound Care Biologics Market, By Region, 2015–2025, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2015 and 2025 (%)
      • Y-o-Y Growth Analysis, For Regions, 2016–2025
    • North America
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of APAC
    • Middle East
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Product Type, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Application, 2015–2025, (US$ Million)
      • Market Size and Forecast, By End User, 2015–2025, (US$ Million)
      • Market Size and Forecast, By Country, 2015–2025, (US$ Million)
        • South Africa
        • Central Africa
        • North Africa
  8. Competitive Landscape
    • Heat Map Analysis
    • Market Share Analysis (3x3 Matrix)
    • Company Profiles
      • Smith & Nephew Plc.*
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Organogenesis, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Integra Lifesciences Holdings Corporation
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Skye Biologics
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Alphatec Holdings, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Solsys Medical LLC
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Amino Technology LLC
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
      • Osiris Therapeutics, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
        • Market Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 38 market data tables and 26 figures on "Wound Care Biologics Market - Global forecast to 2025”.

Research Methodology

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  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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