The global bioactive materials market size was valued at USD 2,015.83 million in 2022 and is anticipated to witness a compound annual growth rate (CAGR) of 14.75% from 2023 to 2030. The increasing adoption of advanced technologies in the medical industry is expected to augment the global bioactive market growth. Increasing investments in healthcare infrastructure and advanced surgical techniques are again expected to drive the market growth. Furthermore, the increasing demand for knee/joint replacement surgeries is further projected to drive bioactive market growth over the forecast period.
Global Bioactive Materials Market: Regional Insights
Regionally, Asia-Pacific is expected to lead the global bioactive materials market in the coming years. The increasing incidence of musculoskeletal diseases and rising awareness regarding the use of these materials in medical procedures are expected to fuel the market growth. Furthermore, technological advancements are further expected to influence the use of these materials in the healthcare industry.
Europe is also expected to register a high CAGR during the forecast period. Increased cancer cases in the region are expected to contribute to growth of the bioactive materials market. Moreover, a rising geriatric population is also expected to increase the demand for bioactive materials in Europe.
Figure 1. Global Bioactive Materials Market Share (%), By Region, 2022
Global Bioactive Materials Market Drivers:
Increasing demand for dental care and root canal treatment to augment market growth
Portland cement or mineral trioxide aggregate (MTA) is a bioactive material that is widely used in the root canal therapy. It is used for maintaining pulp and periodontal tissue vitality as part of pulp capping and perforation repair procedures. Moreover, dentin extracellular matrix proteins (ECMPs) are also important bioactive materials, contain growth factors which can uphold pulp regeneration and tooth healing. The Global Burden of Disease Study 2019 estimated that oral diseases affect close to 3.5 billion people worldwide. Globally, it is estimated that 2 billion people suffer from caries of permanent teeth and 520 million children suffer from caries of primary teeth.
Growing demand from medical sector to foster market growth
Bioactive materials have a great potential for improving the quality of life. They help to suppress the immune system, improve tissue regeneration, and promote bone growth. A number of polymer-based bioactive materials exhibit osteoconductive properties. Collagen fibrin, hyaluronic acid, and chitosan are some examples.
Global Bioactive Materials Market Opportunities:
The emergence of technologically advanced medical devices has provide significant growth opportunities for the global bioactive materials market. Recent research has investigated how these devices modulate biological activity. These studies have been carried out to determine the potential of bioactive materials in promoting tissue regeneration and maintaining the health of patients.
Increased prevalence of arthritis among the elderly population is a major factor expected to bring bright market opportunities. Moreover, the growing age group has also resulted in increased number of surgeries for joint replacement. Besides, the increasing usage of bioactive materials in the pharmaceutical and cosmetic industries is also driving growth of the market. According to OCED data, in 2020, the total number of knee replacements in Canada stood at 198.4 per 100,000 inhabitants, which are increasing annually at a high rate with the rising old generation and increasing arthritis problem in the region.
|Base Year:||2022||Market Size in 2023:||US$ 2,204.6 Mn|
|Historical Data for:||2017 to 2021||Forecast Period:||2023 to 2030|
|Forecast Period 2023 to 2023 CAGR:||14.75 %||2030 Value Projection:||US$ 4,374.64 Mn|
Arthrex Inc, Bioactive Bone Substitutes OyJ, Biomatlante, DSM, Cam Bioceramics, Ceraver, DePuy Synthes (Johnson and Johnson), Medtronic Inc., Noraker, Pulpdent Corporation, Septodont Holding, Stryker Corporation, Zimmer Holdings Inc, Collagen Matrix Inc., OSARTIS GmbHm, Evonik Industries AG, and Boston Scientific Corporation
|Restraints & Challenges:||
Global Bioactive Materials Market Trends:
Bioengineering and tissue engineering are recent trends
Advancement in technology has led to the development of bioengineering and tissues engineering techniques. Moreover, ongoing development on novel drug delivery technologies have further boosted market growth. For instance, in January 2019, DSM Biomedical partnered with ProMed Pharma to leverage its biomedical biomaterials with ProMed’s micro molding and extrusion capabilities to create novel controlled-release drug implants and combination devices.
Porous-coated and fully or partially porous orthopedic implants gaining popularity
Porous-coated and fully porous orthopedic implants are becoming more popular in total ankle replacement surgery. This is mainly due to the improved osseointegration of these implants. Moreover, the use of this coating on the osseous interface of the implant increases the chances of survivorship. These coatings are made of shape memory material that expands once the implant is inserted into the bone. The interconnected networks of pores of the porous surface coats are infiltrated with bone promoting agents. Hence, advent of biomaterials will positively impact the market growth.
Global Bioactive Materials Market Restraints:
Regulatory approval is a major constraint for bioactive materials market
Regulatory approval of bioactive products is a major concern. Drugs, medical devices and biologics are all regulated by the Food and Drug Administration in the United States, to ensure efficacy and safety of any new medical product. Regulatory approvals of all the new medical products is a time consuming process and it is acting as a major challenges for the market.
Negative impact of the Covid-19 is hindering market growth
Due to the lockdown imposed worldwide in order to prevent spread of infection there was disturbance in supply chain and production of bioactive materials. Moreover, pandemic has also adversely affected the research and development in various field. However, the market will witness positive growth in the near future as economy is recovering and getting back to its feet.
Figure 2. Global Bioactive Materials Market Share (%), By Segment Type, 2022
Global Bioactive Materials Market Segmentation:
The global bioactive materials market report is segmented into material type, application, and geography
Based on material type, the market is segmented into Bioactive Glass, Bioactive Ceramics, Bioactive Composites and Other Material Types. Out of which, Bioactive Glass is expected to dominate the global market over the forecast period. Dentistry is one of the core application areas for bioactive materials. Dental restorations are made of moldable bioactive materials, which promote the healing process. Additionally, fast-curing surgical procedures are also increasing the use of bioactive materials.
Bioactive Ceramics segment is also expected to witness significant growth in the near future and this is owing to the growing demand from medical sector for restoring damaged organs.
Based on application, the market is segmented into Dental Care, Nanomedicines and Biotechnology, and Other Applications. Out of which, Dental Care segment is expected to dominate the global market over the forecast period. Bioactive material is widely used for root canal, tooth tissues regeneration, coatings of implants, repair, rebuilding, and regeneration in the field of conservative dentistry.
Others application segment is also expected to witness significant growth in the near future and this is owing to the growing demand from orthopedic and cosmetic surgeries. They are used in bone grafting materials, reinforce soft tissue, and cell therapies.
Global Bioactive Materials Market: Key Developments
In November 2021, BBS-Bioactive Bone Substitutes PLC got patent for the production of ARTEBONE product in the United States.
In February 2021, Noraker constructed the new building, with more than 1500 sqm dedicated to the manufacturing of bioglass solutions, from June 2020 to February 2021.
In March 2021, Noraker joined the French Healthcare Association. With its support, NORAKER aims to promote its Bioglass technology and to continue its international development in particular in the orthopedic field.
In March 2021, The RE-GEN materials have presented dentists with the next advancement in the evolution of resin composite restorations.
Global Bioactive Materials Market: Key Companies Insights
The global bioactive materials market is highly competitive. This is attributed to continuous launch of new technologies due to ongoing R &D and efforts by value chain participants. Moreover, key players are adopting various business growth strategies in order to expand their presence on regional as well as global basis. Some of the key players in the global bioactive materials market are Arthrex Inc, Bioactive Bone Substitutes OyJ, Biomatlante, DSM, Cam Bioceramics, Ceraver, DePuy Synthes (Johnson and Johnson), Medtronic Inc., Noraker, Pulpdent Corporation, Septodont Holding, Stryker Corporation, Zimmer Holdings Inc, Collagen Matrix Inc., OSARTIS GmbHm, Evonik Industries AG, and Boston Scientific Corporation
*Definition: Bioactive materials are used in the pharmaceutical and medical industries. These materials are designed to interact with the physiological fluids in the human body. They act as a carrier for the transport of these fluids
Bioactive materials have many different uses, including tissue engineering, regenerative medicine, diagnostics, and wound repair. They can also have applications in cancer therapy and gene therapy. However, they also have limitations. For instance, they may be ineffective at wound healing. In order to improve these materials, there is a need to develop new bioactive materials and better understanding of mechanisms of their effectiveness. Many biomaterials are designed to exert a strong influence on the activity of a target cell or a tissue. For example, an implant that releases calcium ions, such as in calcium phosphate-based materials, can influence the behavior of a target cell or tissue. Another strategy is to use chemical anti-inflammatory agents that exert surface-modulated biological effects.
Bioactive materials are used in a wide variety of medical applications. These materials are used for implanting, restoring, and regenerating tissue. They are also used in manufacturing antibacterial products and cosmetics. Moreover, the increasing usage of bioactive materials in dentistry applications is expected to boost the market growth. Furthermore, a rapid growth in the number of dental treatments is further expected to drive the demand for orthopedic surgical treatments.
On the other hand, high cost of bioactive material is expected to hamper market growth.
Key features of the study:
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