Global Clinical Mass Spectrometry Market, by Product Type (GAS Chromatography-Mass Spectrometry, Liquid Chromatography-Mass Spectrometry, MALDI TOF Mass Spectrometer, Capillary Electrophoresis-Mass Spectrometry, and Ion Mobility Spectrometry-Mass Spectrometry), by Application (Clinical Testing, Proteomics, and Drug Discovery), by End user (Hospitals, Research Laboratories, and Diagnostic Laboratories), and Geography - Trends and Forecast to 2025

Clinical Mass Spectrometry: Innovative Solution for Diverse Medical Applications

Clinical mass spectrometry serves as a quantitative and qualitative analytical tool for assessment of complex mixtures in all the phases of drug development, including identification of the lead compound and their conformational details. Clinical laboratories use automation for the management of large number of samples through, either total automation systems or high level analyzer automation that are offered by clinical mass spectrometers such as Matrix Assisted Laser Desorption/Ionization (MALDI-TOF). These automated platforms assist effective processing of increasingly large workloads. Thus, clinical laboratories are among the largest end users of this technique. Moreover, the advancement in technology over the recent past, has enabled the ease of measuring and distinguishing separate contributions of molecules such as thyroid hormones and 25-hydroxyl vitamins D2 and D3. Application of translational research in the field of mass spectrometry has resulted in the discovery of blood-based biomarkers, endogenous metabolites, tumor markers, and new disease biomarkers. These advancements are expected to fuel adoption of clinical mass spectrometry devices.

Clinical diagnostic mass spectrometers have the capacity to analyze a limited range of samples such as biomarkers, proteins or drug molecules at once, even in cases of low concentrations thus, making them a valuable tool for diagnostic medical laboratories. Furthermore, it allows researchers to determine pharmacokinetic profiles of drugs that are administered in microdoses. The technology shift from traditional systems to high-resolution technologies such as the Quadrupole-Time of Flight (Q-TOF) mass spectrometry is expected to grow rapidly due to its benefits of accuracy, improved resolution, and sensitivity for clinical diagnostic applications.

The global clinical mass spectrometry market is estimated to be valued at US$ 4,982.5 million in 2017 and is expected to witness a CAGR of 7.3% over the forecast period (2017 – 2025).

Figure 1. Global Clinical Mass Spectrometry Market Share, By Product Type (%)

clinical mass spcetrometry market

Source: Coherent Market Insights Analysis (2017)

Increasing demand for automation in diagnostic techniques to drive growth of the clinical mass spectrometry market

Mass spectrometry enables various diagnostic analyses and study of functional genomics, metabolomics, and proteomics that facilitate development of a cost-effective analytic platform for analysis of samples. The automated laboratory systems provide several high-end functionalities such as MassEXTEND primer extension and nano liter dispensing of samples on to the spectroCHIPS, and data analysis using pre-loaded workstations that make the task of the clinicians and testing personnel easy and less tedious.  Ease of management, quick results, and less complex functionality of these facilities are associated with low costs. Apart from cost- effectiveness, improved quality assays, simplicity, automation, and data reliability, increased sensitivity, reduced cross-reactivity & non-specific binding, and significantly low downtime are advantages offered by mass spectrometers over conventional immunoassays. Moreover, major capital investments associated with the set up and maintenance of these devices poses as a major restraint for the global market growth. Mass spectrometers are largely unaffordable for small diagnostic clinics and laboratories, especially in emerging economies. Moreover, these mass spectrometry methods are labor intensive and require technically skilled professionals. The dearth of these skillful operators is also a constraint for the global clinical mass spectrometry market growth.

Technological advancements leading to new product launch is a prominent factor fueling growth of the clinical mass spectrometry market

Advancements in technology includes miniaturization of mass spectrometry instruments  and increasing automation of the entire spectrometric unit to reduce human efforts and improve efficiency of the instruments. The fully automated analyzer launched by Thermo Fisher in June 2017, is a step closer to achieve entirely automated systems in the mass spectrometry market that can be customized easily to be compatible with the laboratory information systems.

North America held the maximum share of clinical mass spectrometry market in 2016, owing to the presence of major key players and strategic collaborations. The second largest market share is provided by Europe. Under the Federation of analytical Chemistry and Spectrometry Societies, American Society for Mass Spectrometry was formed in 1969, with over 7,500 scientists working together to make advancements in the clinical applications of mass spectrometry and allied topics in academic, industrial, and governmental laboratories. This in turn, creates a strong network of research base in North America thus, contributing to swift growth of the clinical mass spectrometry market. Asia Pacific is also expected to grow at a substantial rate due to increased investments in R&D by various players and government bodies along with the introduction of new in-house manufacturing and R&D facilities.

Clinical mass spectrometry plays a vital role in the drug discovery pipeline for the development of personalized medicines. It is further used for live imaging of biological tissue samples for detection of biomarkers. Cost reduction and improved assay quality has driven the adoption of mass spectrometry. The American Association for Clinical Chemistry (AACC), states that the greater specificity of liquid chromatography–mass spectrometry-(LC MS) enables the measuring of testosterone for patients with low endogenous concentrations. This technique is more reliable than traditional immunoassays, especially for women and children. This led to the early adoption of the most recent generation of instruments using an established technology in the laboratories.  

Market Dynamics

Clinical mass spectrometry offers significant advantages related to clinical research and forensic toxicology applications in terms of speed, robustness, simplicity, and selectivity of small molecules. Clinical mass spectrometry manufacturers are continuously collaborating with clinical diagnostic companies to retain the market share for new products that can quantify low trace levels of disease biomarkers. In Cambridge (U.S.) Thermo Fisher is advancing proteomics and clinical translational research through collaborations at the Biomarkers Research Initiatives in mass spectrometry center. Furthermore, increasing demand for clinical mass spectrometry to perform diagnostic assays in the field of endocrinology, toxicology, leukemia, and biochemical genetics, which helps overcome limitations of conventional immunoassays is also expected to create a favorable environment for growth of the market over the forecast period.

Market Taxonomy

This report segments the global clinical mass spectrometry market on the basis of product type, application, and end user. On the basis of product type, the market is segmented into gas chromatography–mass spectrometry-(GC MS) instrument, liquid chromatography–mass spectrometry-(LC MS) instrument, maldi TOF mass spectrometer, capillary electrophoresis–mass spectrometry, and ion mobility spectrometry-mass spectrometry. Applications of clinical mass spectrometry include clinical testing, proteomics, and drug discovery. On the basis of end user, the clinical mass spectrometry market is segmented into research laboratories, diagnostic laboratories, and hospitals.

Key features of the study:

  • This report provides in-depth analysis of clinical mass spectrometry and provides market size (US$ Million) and cumulative annual growth rate (CAGR %) for the forecast period (2017 – 2025), considering 2016 as the base year.
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launch or approval, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global clinical mass spectrometry market on the basis of the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies, and future plans
  • Key companies covered as part of this study include Agilent Technologies , Waters, Shimadzu Corporation, Danaher, PerkinElmer Inc., Thermo Fisher Scientific Inc., Bruker, Mass Spectrometry Instruments (MSI), and Kore technology
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future type up-gradation, market expansion, and marketing tactics
  • The global clinical mass spectrometry market report caters to various stakeholders in this industry, including investors, researchers, clinical mass spectrometry manufacturers, distributors, new entrants, and financial analysts.
  • Stakeholders would have ease in decision making through the various strategy matrices used in analyzing the clinical mass spectrometry market.

Detailed Segmentation:

  • Global Clinical Mass Spectrometry Market, By Product Type:
    • Gas chromatography–mass spectrometry-(GC MS) instrument
    • Liquid chromatography–mass spectrometry-(LC MS) instrument
    • Maldi TOF mass spectrometer
    • Capillary electrophoresis–mass spectrometry
    • Ion mobility spectrometry-mass spectrometry
  • Global Clinical Mass Spectrometry Market, By Application:
    • Clinical Testing
    • Proteomics
    • Drug Discovery
  • Global Clinical Mass Spectrometry Market, By End User:
    • Research Laboratories
    • Diagnostic Laboratories
    • Hospitals
  • Global Clinical Mass Spectrometry Market, By Geography:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
    • Asia Pacific
      • By Country:
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Rest of Latin America
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
    • Africa
      • By Country:
        • North Africa
        • Central Africa
        • South Africa
      • By Product Type:
        • Gas chromatography–mass spectrometry-(GC MS) instrument
        • Liquid chromatography–mass spectrometry-(LC MS) instrument
        • Maldi TOF mass spectrometer
        • Capillary electrophoresis–mass spectrometry
        • Ion mobility spectrometry-mass spectrometry
      • By Application:
        • Clinical Testing
        • Proteomics
        • Drug Discovery
      • By End User:
        • Research Laboratories
        • Diagnostic Laboratories
        • Hospitals
  • Company Profiles
    • Thermo Fisher Scientific Inc.*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Key Strategies
      • Recent Developments
      • Future Plans
    • Danaher
    • Agilent Technologies
    • Waters
    • Shimadzu Corporation
    • PerkinElmer Inc.
    • Bruker
    • Kore technology
    • Bergman Messgerate Entwicklung KG
    • Mass Spectrometry Instruments (MSI)
    • RGB Photonics
    • ABLE Biosciences

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
        • Supply Side Drivers
        • Demand Side Drivers
        • Economic Drivers
      • Restraints
      • Market Opportunities
      • Impact Analysis
      • Use and Benefit
      • Industry Trends
      • PEST Analysis
  4. Global Clinical Mass Spectrometry Market, By Product Type, 2017 - 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Gas chromatography–mass spectrometry-(GC MS) instrument
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Liquid chromatography–mass spectrometry-(LC MS) instrument
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Maldi TOF mass spectrometer
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Capillary electrophoresis–mass spectrometry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Ion mobility spectrometry-mass spectrometry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
  5. Global Clinical Mass Spectrometry Market, By Application, 2017 - 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Clinical Testing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Proteomics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Drug discovery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
  6. Global Clinical Mass Spectrometry Market, By End User, 2017 - 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Research Laboratories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Diagnostic Laboratories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
    • Hospitals
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Million)
  7. Global Clinical Mass Spectrometry Market, By Regions, 2017 - 2025, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017 - 2025
    • North America
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Russia
        • Others
    • Asia Pacific
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • China
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Others
    • Latin America
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • Brazil
        • Mexico
        • Others
    • Africa
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • Northern Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Product, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Application, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By End User, 2017 - 2025, (US$ Million)
      • Market Size and Forecast, By Country, 2017 - 2025, (US$ Million)
        • GCC Countries
        • Israel
        • Others
  8. Competitive Landscape
    • Heat Map Analysis
    • Market Share Analysis
    • Company Profiles
      • Bruker
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Kore technology
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Bergman Messgerate Entwicklung KG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Mass Spectrometry Instruments (MSI)
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • RGB Photonics
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • ABLE Biosciences
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Thermo Fisher Scientific Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Danaher
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Agilent Technologies
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Waters
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • Shimadzu Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
      • PerkinElmer Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Future Plans
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 34 market data tables and 27 figures on "Clinical Mass Spectrometry Market - Global forecast to 2025”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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