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  • Published On : Dec 2020
  • Code : CMI4306
  • Industry : Pharmaceutical
  • Pages : 180
  • Formats :

Idiopathic hypersomnia (IH) is a rare sleep disorder marked by an over sleeping duration time during the day even after a longer sleeping hours of night sleep. People with idiopathic hypersomnia sleep normal or for long hours each night but still feel excessively sleepy during the day. Idiopathic hypersomnia is a type of hypersomnia and symptoms include chronic excessive daytime sleepiness (EDS), non-refreshing daytime napping, sleep drunkenness after nighttime sleep, naps, and others. Idiopathic hypersomnia is a nervous system disease, whose cause is not known. There is no single drug available that is approved by the U.S. FDA for this disease, but medicines such as dextroamphetamine that are approved for narcolepsy, one of the types of hypersomnia can be used for idiopathic hypersomnia off-label.

The global idiopathic hypersomnia treatment market is estimated to be valued at US$ 242.4 million in 2020 and is expected to exhibit a CAGR of 8.7% over the forecast period (2020-2027).

Figure 1. Global Idiopathic Hypersomnia Treatment Market Share (%) in Terms of Value, By Region, 2020

Idiopathic Hypersomnia Treatment  | Coherent Market Insights

Increase in lifestyle diseases such as anxiety, depression, and increasing diagnosis rate of hypersomnia are expected to drive the market growth over the forecast period 

Growing incidence of lifestyle diseases such as anxiety, depression, etc. caused by behavioral changes, social activities, which affects the sleep cycle is the major factor responsible for growth of the global idiopathic hypersomnia treatment market. These changes lead to anxiety, depression, & other health issues, in which patients feel tired during the daytime and are more prone to hypersomnia. For instance, according to the Anxiety and Depression Association of America, anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the U.S. of age 18 and older, or 18.1% of the population every year.

Furthermore, increasing diagnosis rate of hypersomnia coupled with technological advancements for diagnosis of hypersomnia are expected to fuel growth of the global idiopathic hypersomnia treatment market. For instance, multiple sleep latency test (MSLT) is the standard tool used to diagnose narcolepsy and idiopathic hypersomnia, which is offered at AASM-accredited sleep centers in the U.S.

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Idiopathic Hypersomnia Treatment Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2019: US$ 242.4 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 8.7% 2027 Value Projection: US$ 429.0 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Drug Class: Stimulant Medications, Non-stimulant wake-promoting Medications, Sodium Oxybate.
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.
Companies covered:

Takeda Pharmaceutical Company Limited, Teva Pharmaceutical Industries Ltd., Jazz Pharmaceuticals, Inc., BIOPROJET, Avadel Pharmaceuticals, Plc. GlaxoSmithKline plc, Pfizer Inc., Theranexus, Fisher & Paykel Healthcare Limited, Drive DeVilbiss Healthcare LLC, and Merck & Co. Inc.

Growth Drivers:
  • Increasing prevalence of lifestyle diseases
  • Growing number of pipeline products
Restraints & Challenges:
  • No regulatory approved product
  • Side effect of current off-label drugs

Figure 2. Global Idiopathic Hypersomnia Treatment Market Share (%), by Drug Class, 2020

Idiopathic Hypersomnia Treatment  | Coherent Market Insights

Increasing number of pipeline products is expected to drive the market growth over the forecast period

Rising number of pipeline products for idiopathic hypersomnia treatment is also a major factor that is expected to boost growth of the global idiopathic hypersomnia treatment market. For instance, in January 2020, Millennium Pharmaceuticals, Inc., a subsidiary of Takeda Pharmaceutical Company Limited initiated the phase1 study of a single intravenous infusion dose of TAK-925 in participants with idiopathic hypersomnia.

Global Idiopathic Hypersomnia Treatment – Impact of Coronavirus (Covid-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization declared it a public health emergency. According to the World Health Organization’s report, the manifestation of coronavirus disease (COVID-19) has resulted in over 45 million infected individuals worldwide as of October 30, 2020. Due to the increasing prevalence of COVID-19, key players operating in the idiopathic hypersomnia treatment market are focusing on research and development of novel products to support and combat the effect of COVID-19. COVID-19 pandemic has impacted the global economy and in turn, the idiopathic hypersomnia treatment market. Quarantines, traveling constraints, and social distancing measures are likely to lead to a steep decline in business and consumer spending until the end of the third quarter of 2020

Global Idiopathic Hypersomnia Treatment Market - Restraint

Side effects of current off-label drugs for hypersomnia which include aggressive behavior & dependence and no approved product are some of the major factors that are expected to hinder growth of the global idiopathic hypersomnia treatment market. Moreover, declining less patient pool for clinical trials is also a major setback for the global idiopathic hypersomnia treatment market, which is expected to hamper growth of the market.

Key Players

Major players operating in the global idiopathic hypersomnia treatment market include Takeda Pharmaceutical Company Limited, Teva Pharmaceutical Industries Ltd., Jazz Pharmaceuticals, Inc., BIOPROJET, Avadel Pharmaceuticals, Plc. GlaxoSmithKline plc, Pfizer Inc., Theranexus, Fisher & Paykel Healthcare Limited, Drive DeVilbiss Healthcare LLC, and Merck & Co. Inc.

Idiopathic hypersomnia is a rare sleep disease that causes a person to be excessively sleepy during the day even after a good or prolonged night's sleep. It also causes difficulty in waking up among patients after a night sleep or a nap. Moreover, narcolepsy and idiopathic hypersomnia are both types of hypersomnia but there are differences, which can be observed by diagnostic tests such as Polysomnography (PSG) that lies in the number of sleep-onset REM periods (SOREMPs). Patients with narcolepsy have two or more SOREMPs from Polysomnography (PSG) and Multiple Sleep Latency Test (MSLT) results, whereas patients with idiopathic hypersomnia do not. There are symptomatic treatment such as increase wakefullness options available for idiopathic hypersomnia, while there is not a single approved drugs for this disease.

Market Dynamics

Rising number of pipeline products and increasing cases of lifestyle diseases are some of the major factors responsible for growth of the global idiopathic hypersomnia treatment Market. For instance, in October 2020, Jazz Pharmaceuticals announced positive topline results from a phase 3 study evaluating Xywav (calcium, magnesium, potassium, and sodium oxybates) for the treatment of idiopathic hypersomnia that showed that the trial met the primary point (measured Epworth Sleepiness Scale (ESS) and key secondary end points [Patient Global Impression of Change (PGIc) and Idiopathic Hypersomnia Severity Scale (IHSS)].

Key features of the study:

  • This report provides in-depth analysis of the global idiopathic hypersomnia treatment market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2020–2027), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global idiopathic hypersomnia treatment market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include Takeda Pharmaceutical Company Limited, Teva Pharmaceutical Industries Ltd., Jazz Pharmaceuticals, Inc., BIOPROJET, Avadel Pharmaceuticals, Plc. GlaxoSmithKline plc, Pfizer Inc., Theranexus, Fisher & Paykel Healthcare Limited, Drive DeVilbiss Healthcare LLC, and Merck & Co. Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global idiopathic hypersomnia treatment market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global idiopathic hypersomnia treatment Market

Detailed Segmentation:

  • Global Idiopathic Hypersomnia Treatment Market, By Drug Class:
    • Stimulant Medications
    • Non-stimulant wake-promoting Medications
    • Sodium Oxybate
  • Global Idiopathic Hypersomnia Treatment Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Global Idiopathic Hypersomnia Treatment Market, By Region:
    • North America
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Drug Class:
        • Stimulant Medications
        • Non-stimulant wake-promoting Medications
        • Sodium Oxybate
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Takeda Pharmaceutical Company Limited*
      • Company Overview
      • Material Portfolio
      • Financial Performance
      • Key Highlights
      • Market Strategies
    • Teva Pharmaceutical Industries Ltd.
    • Jazz Pharmaceuticals, Inc.
    • BIOPROJET
    • Avadel Pharmaceuticals, Plc.
    • GlaxoSmithKline plc
    • Pfizer Inc.
    • Theranexus
    • Fisher & Paykel Healthcare Limited
    • Drive DeVilbiss Healthcare LLC
    • Merck & Co. Inc.

 “*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

The global idiopathic hypersomnia treatment market size is estimated to be valued at US$ 242.4 million in 2020 and is expected to exhibit a CAGR of 8.7% between 2020 and 2027.
Increasing lifestyle diseases, growing number of pipeline products, and increasing diagnosis rate are expected to drive the market growth over the forecast period.
Stimulant medications is the leading drug class segment in the idiopathic hypersomnia treatment market.
North America is expected to hold the largest market share in the global idiopathic hypersomnia treatment market.
Side effects of off-label drugs and less patient pool for clinical trials are the major factors restraining growth of the idiopathic hypersomnia treatment market.
Major players operating in the global idiopathic hypersomnia treatment include Takeda Pharmaceutical Company Limited, Teva Pharmaceutical Industries Ltd., Jazz Pharmaceuticals, Inc., BIOPROJET, Avadel Pharmaceuticals, Plc. GlaxoSmithKline plc, Pfizer Inc., Theranexus, Fisher & Paykel Healthcare Limited, Drive DeVilbiss Healthcare LLC, and Merck & Co. Inc.

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