Eisenmenger Syndrome Treatment Market, by Drug Type (Antiarrhythmic Agents, Blood Thinning Agents, Endothelin Receptor Antagonist, and Others), by Distribution Channel (Hospital Pharmacies, Online Pharmacies, and Retail Pharmacies), by Geography - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026

  • To Be Published : Aug 2019 |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Eisenmenger Syndrome develops due to high blood pressure in the lungs, which is known as pulmonary hypertension. Pulmonary hypertension occurs due to certain congenital heart defects that cause the blood to flow from left side of the heart to right side abnormally (left-to-right shunt). The congenital heart defects causing this condition include Patent ductus arteriosus (PDA), atrial septal defect (ASD), Ventricular septal defect (VSD), and Atrioventricular canal defect (AV canal). The reversal of this shunt i.e. movement of blood from right side of the heart back to left side (right-to-left shunt) causes insufficient oxygen supply in the blood. This reversal occurs due to increase in blood pressure on the right side of the heart, which causes the blood to flow back to the left side, resulting in mixing of oxygenated and deoxygenated blood, in turn less oxygen supply in the blood. Moreover, continuous high pressure in the lungs causes’ irreversible damage to the blood vessels, fibrosis leading to thrombus formation. These changes are termed as pulmonary vascular obstructive disease or secondary pulmonary arterial hypertension (PAH). The treatment for this condition depends on individual patient’s condition and symptoms. Generally, the treatment includes relieving the symptoms and associated co-morbidities. Medications such as calcium channel blockers, antiarrhythmic agents, and blood thinning agents are prescribed by the physician.

Eisenmenger Syndrome Treatment Market Drivers

Continuous requirement of medication supports the growth of the Eisenmenger Syndrome Treatment Market. Eisenmenger Syndrome is a chronic disease and requires medication to be taken for a long period of time. The incidence and prevalence of Eisenmenger syndrome has not been properly defined due to the highly specific nature of the condition. However, according to National Center for Biotechnology Information (NCBI), 2010, an estimated 8% of patients with congenital heart disease are expected to develop Eisenmenger syndrome. According to Centers for Disease Control and Prevention (CDC), Congenital Heart Diseases affects nearly 1% or about 40,000 of the births per year in the U.S., 2018. Though technological and healthcare advancements have made it possible to correct congenital heart defects, the responses have been poor in case of patients suffering from Eisenmenger syndrome. Absence of treatment option which may cure the condition has fostered the growth of the global Eisenmenger syndrome treatment market, as physicians and patients have to rely on available therapies for the treatment. Most of the medications have generic versions available in the market, which has supported the growth of the market. Presence of disease targeting therapies such as Sildenafil and Bosentan have boosted the market growth over the past years and the trend is expected to remain the same, owing to unavailability of alternative options. Moreover, combination therapies is also expected to boost the growth of the market over the forecast period. European Society of Cardiology Consensus Guidelines, 2015, suggest the use of combination therapy (Sildenafil + Bosentan, and others) in the management of pulmonary hypertension. These factors are expected to boost growth of the market over forecast period.

Despite presence of disease targeting therapies such as Sildenafil, and Bosentan the survival prospects for patients suffering from Eisenmenger syndrome have continuously been low, and the prevalence of patients suffering from Eisenmenger syndrome has decreased in the developed economies such as North America and Europe. The main reason behind this is sophisticated surgical approach in the treatment in curing the congenital heart defects and fetal screening with echocardiography in early life for heart defects. Moreover, Actelion Pharmaceuticals, Ltd.’s drug Opsumit (macitentan) showed lower than expected results in the Phase 3 clinical trials in 2017. These factors are expected to restrain growth of the global Eisenmenger Syndrome Treatment Market. 

Eisenmenger Syndrome Treatment Market Regional Insights

Emerging economies such as Asia Pacific and Latin America are expected to witness significant growth in the Eisenmenger Syndrome treatment market over the forecast period due to reliance on available medication for the long term treatment. Government organizations from developed regions such as North America have supported the growth of the market through spreading awareness about the condition. Organizations such as American Heart Association (AHA), Congenital Heart Information Network (C.H.I.N.), Genetic and Rare Diseases (GARD) Information Center, and National Organization for Rare Disorders (NORD) keep track of Eisenmenger syndrome and related conditions. 

Key players operating in Eisenmenger Syndrome Treatment Market include Actelion Pharmaceuticals Ltd., Gilead Sciences, Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., AstraZeneca plc., Novartis AG, Merck & Co., Inc., GlaxoSmithKline plc., Mylan N.V., and Bayer AG.

Eisenmenger Syndrome Treatment Market Taxonomy-

The global eisenmenger syndrome treatment market is segmented on the basis of drug type, distribution channel, and geography.

By Drug Type-

  • Antiarrhythmic Agents
  • Blood Thinning Agents
  • Endothelin Receptor Antagonist
  • Others

By Distribution Channel-

  • Hospital Pharmacies
  • Online Pharmacies
  • Retail Pharmacies

By Geography-

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Smiley face

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.
Smiley face

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Choose License Type

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

[email protected]

Key Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.